Abstract
SUMMARY: In this study, we compared lesion size by using VADC and VT2 at 0, 2, 5, 24, and 48 hours and histologic lesions at 48 hours in a P7 rat stroke model. The best correlation between VHISTO and VADC was at H0, and between VHISTO and VT2, at H2-H5. Early MR imaging signals allowed excluding “no-lesion” and “no-reflow” animals to help standardize this neonatal stroke model and predict lesion size.
Abbreviations
- H0, H2, H5, H24, and H48
- 15 minutes and 2, 5, 24, and 48 hours after reperfusion, respectively
- P7
- 7-day-old
- RARE
- rapid acquisition relaxation excitement
- VADC
- volume of lesion on ADC maps
- VHISTO
- volume of lesion on histologic sections
- VT2
- volume of lesion on T2 maps
- © 2014 American Society of Neuroradiology
Indicates open access to non-subscribers at www.ajnr.org
Jump to section
Related Articles
Cited By...
- No citing articles found.