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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 25:210-213, February 2004
© 2004 American Society of Neuroradiology

Case Report
BRAIN

Early Diagnosis of Central Pontine Myelinolysis with Diffusion-Weighted Imaging

Kimberly A. Ruzek^a, Norbert G. Campeau^a and Gary M. Miller^a

^a From the Mayo Clinic, Department of Radiology, Rochester, Minnesota

Address correspondence to Norbert G. Campeau, MD, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905

Summary: Central pontine myelinolysis (CPM) occurs in the setting of rapidly corrected hyponatremia, especially in chronically debilitated patients. Conventional CT and MR imaging findings lag the clinical manifestations of CPM. We present a case in which restricted diffusion was identified within the central pons by using MR diffusion-weighted imaging within 24 hours of onset of patient tetraplegia and before findings were conspicuous with conventional MR imaging sequences (T1, T2, and fluid-attenuated inversion recovery).

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