Abstract
BACKGROUND AND PURPOSE: The safety and efficacy of SBCAS have not been evaluated in detail. The purpose of our study was to evaluate the outcome after SBCAS in high-risk patients compared with unilateral stent placement.
MATERIALS AND METHODS: Between March 2002 and October 2008, a total of 205 consecutive high-risk patients underwent CAS at our institution. Of these patients, 30 (14.6%) underwent SBCAS (n = 24) and staged SBCAS (n = 6). Patients who underwent unilateral CAS (n = 175) during the same period served as controls. The stroke risk factors, procedural results, and outcome at 30 days and 6 months, as well as the restenosis rate at 6 months, were compared by using either the χ2 test or the Kruskal-Wallis equality-of-populations rank test.
RESULTS: Our data revealed no significant differences in the stroke risk factors between the SBCAS and the control group. HPS occurred more commonly in SBCAS (ie, 16.7%, 4/24) compared with 2.9% (5/175) in the control group (P = .014). However, there was no statistical significance between 2 groups in the event rate of stroke (minor and/or major stroke), death, or restenosis at 6 months.
CONCLUSIONS: There was no significant difference in outcome at 6 months following stent placement between SBCAS and unilateral CAS in the high-risk patient group, even though HPS occurred more commonly after SBCAS.
Abbreviations
- BP
- blood pressure
- CAS
- carotid artery stent placement
- CEA
- carotid endarterectomy
- CCS
- Canadian Cardiovascular Society
- FEV
- forced expiratory volume
- HD
- hemodynamic depression
- HPS
- hyperperfusion syndrome
- mRS
- modified Rankin scale
- NASCET
- North American Symptomatic Carotid Endarterectomy Trial
- NIHSS
- National Institutes of Health Stroke Scale
- NYHA
- New York Heart Association
- SBCAS
- simultaneous bilateral carotid artery stent placement
- TIA
- transient ischemic attack
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