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Abstract

Partial development of the corpus callosum.

D Rubinstein, V Youngman, J H Hise and T R Damiano
American Journal of Neuroradiology May 1994, 15 (5) 869-875;
D Rubinstein
University of Colorado Health Sciences Center, Department of Radiology, Denver 80262.
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V Youngman
University of Colorado Health Sciences Center, Department of Radiology, Denver 80262.
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J H Hise
University of Colorado Health Sciences Center, Department of Radiology, Denver 80262.
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T R Damiano
University of Colorado Health Sciences Center, Department of Radiology, Denver 80262.
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Abstract

PURPOSE To determine whether the MR findings of callosal dysgenesis suggest that the partially formed corpus callosum in humans is the result of arrested growth or delayed continued development.

METHODS The MR scans of 25 patients with callosal dysgenesis were reviewed to determine whether the observed corpus callosum corresponded to the form and position of a portion of a normal corpus callosum, as suggested by a theory of arrested growth.

RESULTS In 10 of the 25 cases, the partially formed corpus callosum corresponded to a portion of a normal corpus callosum. In the remaining 15 cases, the partially formed corpus callosum was located posterior to the expected location of a normal genu and inferior to the expected location of a normal body.

CONCLUSIONS Corpus callosum dysgenesis in humans may be caused by arrested growth in some cases; in other cases it is most likely caused by delayed continued development that attempts to compensate for earlier abnormalities in the evolution of midline structures.

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American Journal of Neuroradiology
Vol. 15, Issue 5
1 May 1994
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Partial development of the corpus callosum.
D Rubinstein, V Youngman, J H Hise, T R Damiano
American Journal of Neuroradiology May 1994, 15 (5) 869-875;

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Partial development of the corpus callosum.
D Rubinstein, V Youngman, J H Hise, T R Damiano
American Journal of Neuroradiology May 1994, 15 (5) 869-875;
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