Research ArticleBRAIN
Histopathologic Analysis of Foci of Signal Loss on Gradient-Echo T2*-Weighted MR Images in Patients with Spontaneous Intracerebral Hemorrhage: Evidence of Microangiopathy-Related Microbleeds
Franz Fazekas, Reinhold Kleinert, Gudrun Roob, Gertrude Kleinert, Peter Kapeller, Reinhold Schmidt and Hans-Peter Hartung
American Journal of Neuroradiology April 1999, 20 (4) 637-642;
Franz Fazekas
Reinhold Kleinert
Gudrun Roob
Gertrude Kleinert
Peter Kapeller
Reinhold Schmidt
References
- ↵Caplan LR. Intracerebral hemorrhage. In: Tyler HR, Dawson D, eds. Current Neurology. Boston: Houghton-Mifflin; 1979;2:185–205
- Brott T, Thalinger K, Hertzberg V. Hypertension as a risk factor for spontaneous intracerebral hemorrhage. Stroke 1986;17:1078-1083
- ↵Wagle WA, Smith TW, Weiner M. Intracerebral hemorrhage caused by cerebral amyloid angiopathy: radiographic-pathologic correlation. AJNR Am J Neuroradiol 1984;5:171-176
- Vinters HA. Cerebral amyloid angiopathy: a critical review. Stroke 1987;2:311-324
- ↵Selekler K, Erzen C. Leukoaraiosis and intracerebral hematoma. Stroke 1989;20:1016-1020
- Inzitari D, Giordano GP, Ancona AL, Pracucci G, Mascalchi M, Amaducci L. Leukoaraiosis, intracerebral hemorrhage, and arterial hypertension. Stroke 1990;21:1419-1423
- ↵Atlas SW, Mark AS, Grossman RI, Gomori JM. Intracranial hemorrhage: gradient-echo MR imaging at 1.5 T: comparison with spin-echo imaging and clinical applications. Radiology 1988;168:803-807
- ↵Offenbacher H, Fazekas F, Schmidt R, Koch M, Fazekas G, Kapeller P. MR of cerebral abnormalities concomitant with primary intracerebral hematomas. AJNR Am J Neuroradiol 1996;17:573-578
- ↵Greenberg SM, Finkelstein SP, Schaefer PW. Petechial hemorrhages accompanying lobar hemorrhage: detection by gradient-echo MRI. Neurology 1996;46:1751-1754
- ↵Fazekas F, Kleinert R, Offenbacher H, et al. The morphologic correlate of incidental white matter hyperintensities on MR images. AJNR Am J Neuroradiol 1991;12:915-921
- ↵Fazekas F, Chawluk JB, Alavi A, Hurtig HI, Zimmerman RA. MR signal abnormalities at 1.5T in Alzheimer's dementia and normal aging. AJNR Am J Neuroradiol 1987;8:421-426
- ↵Vonsattel JPG, Myers RH, Hedley-Whyte ET, Ropper AH, Bird ED, Richardson EP Jr. Cerebral amyloid angiopathy without and with cerebral hemorrhages: a comparative histological study. Ann Neurol 1991;30:637-649
- ↵Chan S, Kartha K, Yoon SS, Desmond DW, Hilal SK. Multifocal hypointense cerebral lesions on gradient-echo MR are associated with chronic hypertension. AJNR Am J Neuroradiol 1996;17:1821-1827
- Roob G, Schmidt R, Kapeller P, Lechner A, Hartung HP, Fazekas F. MRI evidence of past cerebral microbleeds in a healthy elderly population. Neurology 1999;52:991-994
- ↵Lammie GA, Brannan F, Slattery J, Warlow C. Nonhypertensive cerebral small-vessel disease: an autopsy study. Stroke 1997;28:2222-2229
- ↵The SPIRIT Study Group. A randomized trial of anticoagulants versus aspirin after cerebral ischemia of presumed arterial origin: the Stroke Prevention in Reversible Ischemia Trial (SPIRIT). Ann Neurol 1997;42:857-865
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Histopathologic Analysis of Foci of Signal Loss on Gradient-Echo T2*-Weighted MR Images in Patients with Spontaneous Intracerebral Hemorrhage: Evidence of Microangiopathy-Related Microbleeds
Franz Fazekas, Reinhold Kleinert, Gudrun Roob, Gertrude Kleinert, Peter Kapeller, Reinhold Schmidt, Hans-Peter Hartung
American Journal of Neuroradiology Apr 1999, 20 (4) 637-642;
Histopathologic Analysis of Foci of Signal Loss on Gradient-Echo T2*-Weighted MR Images in Patients with Spontaneous Intracerebral Hemorrhage: Evidence of Microangiopathy-Related Microbleeds
Franz Fazekas, Reinhold Kleinert, Gudrun Roob, Gertrude Kleinert, Peter Kapeller, Reinhold Schmidt, Hans-Peter Hartung
American Journal of Neuroradiology Apr 1999, 20 (4) 637-642;
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