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Research ArticleBRAIN

Isolated Demyelinating Syndromes: Comparison of Different MR Imaging Criteria to Predict Conversion to Clinically Definite Multiple Sclerosis

Mar Tintoré, Alex Rovira, Maria J. Martínez, Jordi Rio, Pablo Díaz-Villoslada, Luis Brieva, Cecilia Borrás, Elisenda Grivé, Jaume Capellades and Xavier Montalban
American Journal of Neuroradiology April 2000, 21 (4) 702-706;
Mar Tintoré
aFrom the Unit of Clinical Neuroimmunology, Department of Neurology (M.T., J.R., P.D.-V., L.B., C.B., X.M.), and the Magnetic Resonance Unit (I.D.I.), Department of Radiology (A.R., M.J.M., E.G., J.C.), Vall d'Hebron University Hospitals, Barcelona, Spain.
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Alex Rovira
aFrom the Unit of Clinical Neuroimmunology, Department of Neurology (M.T., J.R., P.D.-V., L.B., C.B., X.M.), and the Magnetic Resonance Unit (I.D.I.), Department of Radiology (A.R., M.J.M., E.G., J.C.), Vall d'Hebron University Hospitals, Barcelona, Spain.
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Maria J. Martínez
aFrom the Unit of Clinical Neuroimmunology, Department of Neurology (M.T., J.R., P.D.-V., L.B., C.B., X.M.), and the Magnetic Resonance Unit (I.D.I.), Department of Radiology (A.R., M.J.M., E.G., J.C.), Vall d'Hebron University Hospitals, Barcelona, Spain.
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Jordi Rio
aFrom the Unit of Clinical Neuroimmunology, Department of Neurology (M.T., J.R., P.D.-V., L.B., C.B., X.M.), and the Magnetic Resonance Unit (I.D.I.), Department of Radiology (A.R., M.J.M., E.G., J.C.), Vall d'Hebron University Hospitals, Barcelona, Spain.
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Pablo Díaz-Villoslada
aFrom the Unit of Clinical Neuroimmunology, Department of Neurology (M.T., J.R., P.D.-V., L.B., C.B., X.M.), and the Magnetic Resonance Unit (I.D.I.), Department of Radiology (A.R., M.J.M., E.G., J.C.), Vall d'Hebron University Hospitals, Barcelona, Spain.
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Luis Brieva
aFrom the Unit of Clinical Neuroimmunology, Department of Neurology (M.T., J.R., P.D.-V., L.B., C.B., X.M.), and the Magnetic Resonance Unit (I.D.I.), Department of Radiology (A.R., M.J.M., E.G., J.C.), Vall d'Hebron University Hospitals, Barcelona, Spain.
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Cecilia Borrás
aFrom the Unit of Clinical Neuroimmunology, Department of Neurology (M.T., J.R., P.D.-V., L.B., C.B., X.M.), and the Magnetic Resonance Unit (I.D.I.), Department of Radiology (A.R., M.J.M., E.G., J.C.), Vall d'Hebron University Hospitals, Barcelona, Spain.
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Elisenda Grivé
aFrom the Unit of Clinical Neuroimmunology, Department of Neurology (M.T., J.R., P.D.-V., L.B., C.B., X.M.), and the Magnetic Resonance Unit (I.D.I.), Department of Radiology (A.R., M.J.M., E.G., J.C.), Vall d'Hebron University Hospitals, Barcelona, Spain.
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Jaume Capellades
aFrom the Unit of Clinical Neuroimmunology, Department of Neurology (M.T., J.R., P.D.-V., L.B., C.B., X.M.), and the Magnetic Resonance Unit (I.D.I.), Department of Radiology (A.R., M.J.M., E.G., J.C.), Vall d'Hebron University Hospitals, Barcelona, Spain.
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Xavier Montalban
aFrom the Unit of Clinical Neuroimmunology, Department of Neurology (M.T., J.R., P.D.-V., L.B., C.B., X.M.), and the Magnetic Resonance Unit (I.D.I.), Department of Radiology (A.R., M.J.M., E.G., J.C.), Vall d'Hebron University Hospitals, Barcelona, Spain.
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References

  1. ↵
    Sandberg-Wollheim M, Bynke H, Cronqvist S, Holtas S, Platz P, Ryder LP. A long-term prospective study of optic neuritis: evaluation of risk factors. Ann Neurol 1990;27:386-393
    CrossRefPubMed
  2. ↵
    Ormerod IE, Miller DH, McDonald WI, et al. The role of NMR imaging in the assessment of multiple sclerosis and isolated neurological lesions: a quantitative study. Brain 1987;110:1579-1616
    CrossRefPubMedWeb of Science
  3. ↵
    Beck RW, Cleary PA, Anderson MM Jr, et al. A randomized, controlled trial of corticosteroids in the treatment of acute optic neuritis: The Optic Neuritis Study Group. N Engl J Med 1992;27:581-588
  4. Ford B, Tampieri D, Francis G. Long-term follow-up of acute partial transverse myelopathy. Neurology 1992;42:250-252
    Abstract/FREE Full Text
  5. Miller DH, Ormerod IE, Gibson A, du Boulay EP, Rudge P, McDonald WI. MR brain scanning in patients with vasculitis: differentiation from multiple sclerosis. Neuroradiology 1987;29:226-231
    CrossRefPubMedWeb of Science
  6. Río J, Nos C, Rovira A, Tintoré M, Codina A, Montalbán X. The development of multiple sclerosis following an isolated episode of optic neuritis: magnetic resonance study. Med Clin (Barc) 1997;109:370-372
    PubMed
  7. ↵
    Tintoré M, Rovira A, Río J, Hernández D, Marzo ME, Montalbán X. Optic neuritis brainstem syndromes and myelitis: early conversion to multiple sclerosis. Med Clin (Barc) 1999;112:693-694
    PubMed
  8. ↵
    Filippi M, Horsfield MA, Morrissey SP, et al. Quantitative brain MRI lesion load predicts the course of clinically isolated syndromes suggestive of multiple sclerosis. Neurology 1994;44:635-641
    Abstract/FREE Full Text
  9. ↵
    O'Riordan JI, Thompson AJ, Kingsley DP, et al. The prognostic value of brain MRI in clinically isolated syndromes of the CNS: a 10-year follow-up. Brain 1998;121:495-503
    CrossRefPubMedWeb of Science
  10. ↵
    Paty DW, Oger JJ, Kastrukoff LF, et al. MRI in the diagnosis of MS: a prospective study with comparison of clinical evaluation, evoked potentials, oligoclonal banding, and CT. Neurology 1988;38:180-185
    Abstract/FREE Full Text
  11. ↵
    Lee KH, Hashimoto SA, Hooge JP, et al. Magnetic resonance imaging of the head in the diagnosis of multiple sclerosis: a prospective 2-year follow-up with comparison of clinical evaluation, evoked potentials, oligoclonal banding, and CT. Neurology 1991;41:657-660
    Abstract/FREE Full Text
  12. ↵
    Fazekas F, Offenbacher H, Fuchs S, et al. Criteria for an increased specificity of MRI interpretation in elderly subjects with suspected multiple sclerosis. Neurology 1988;38:1822-1825
    Abstract/FREE Full Text
  13. ↵
    Offenbacher H, Fazekas F, Schmidt R, et al. Assessment of MRI criteria for a diagnosis of MS. Neurology 1993;43:905-909
    Abstract/FREE Full Text
  14. ↵
    Tas MW, Barkhol F, van Walderveen MA, Polman CH, Hommes OR, Valk J. The effect of gadolinium on the sensitivity and specificity of MR in the initial diagnosis of multiple sclerosis. AJNR Am J Neuroradiol 1995;16:259-264
    Abstract/FREE Full Text
  15. ↵
    Barkhof F, Filippi M, Miller DH, et al. Comparison of MRI criteria at first presentation to predict conversion to clinically definite multiple sclerosis. Brain 1997;120:2059-2069
    CrossRefPubMedWeb of Science
  16. ↵
    Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research proposals. Ann Neurol 1983;13:227-231
    CrossRefPubMedWeb of Science
  17. Filippini G, Comi GC, Cosi V, et al. Sensitivities and predictive values of paraclinical tests for diagnosing multiple sclerosis. J Neurol 1994;241:132-137
    CrossRefPubMedWeb of Science
  18. Miller DH, Ormerod IE, Rudge P, Kendall BE, Moseley IF, McDonald WI. The early risk of multiple sclerosis following isolated acute syndromes of the brainstem and spinal cord. Ann Neurol 1989;26:635-639
    CrossRefPubMedWeb of Science
  19. Sharief MK, Thompson EJ. The predictive value of intrathecal immunoglobulin synthesis and magnetic resonance imaging in acute isolated syndromes for subsequent development of multiple sclerosis. Ann Neurol 1991;29:147-151
    CrossRefPubMedWeb of Science
  20. ↵
    Morrissey SP, Miller DH, Kendall BE, et al. The significance of brain magnetic resonance imaging abnormalities at presentation with clinically isolated syndromes suggestive of multiple sclerosis: a 5-year follow-up study. Brain 1993;116:135-146
    CrossRefPubMedWeb of Science
  21. Miller DH, Albert PS, Barkhof F, et al. Guidelines for the use of magnetic resonance techniques in monitoring the treatment of multiple sclerosis: US National MS Society Task Force. Ann Neurol 1996;39:6-16
    CrossRefPubMedWeb of Science
  22. ↵
    Filippi M, van Waesberghe JH, Horsfield MA, et al. Interscanner variation in brain MRI lesion load measurements in MS: implications for clinical trials. Neurology 1997;49:371-377
    Abstract/FREE Full Text
  23. Molyneaux PD, Tubridy N, Parker GJM, et al. The effect of section thickness on MR lesion detection and quantification in multiple sclerosis. AJNR Am J Neuroradiol 1998;19:1715-1720
    Abstract
  24. Yousry TA, Filippi M, Becker C, Horsfield MA, Voltz R. Comparison of MR pulse sequences in the detection of multiple sclerosis lesions. AJNR Am J Neuroradiol 1997;18:959-963
    Abstract/FREE Full Text
  25. ↵
    Lee DH, Vellet AD, Eliasziw M, et al. MR imaging field strength: prospective evaluation of the diagnostic accuracy of MR for diagnosis of multiple sclerosis at 0.5 and 1.5 T. Radiology 1995;194:257-262
    PubMedWeb of Science
  26. ↵
    O'Riordan JI, Losseff NA, Phatouros C, et al. Asymptomatic spinal cord lesions in clinically isolated optic nerve, brain stem, and spinal cord syndromes suggestive of demyelination. J Neurol Neurosurg Psychiatry 1998;64:353-357
    Abstract/FREE Full Text
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Mar Tintoré, Alex Rovira, Maria J. Martínez, Jordi Rio, Pablo Díaz-Villoslada, Luis Brieva, Cecilia Borrás, Elisenda Grivé, Jaume Capellades, Xavier Montalban
Isolated Demyelinating Syndromes: Comparison of Different MR Imaging Criteria to Predict Conversion to Clinically Definite Multiple Sclerosis
American Journal of Neuroradiology Apr 2000, 21 (4) 702-706;

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Isolated Demyelinating Syndromes: Comparison of Different MR Imaging Criteria to Predict Conversion to Clinically Definite Multiple Sclerosis
Mar Tintoré, Alex Rovira, Maria J. Martínez, Jordi Rio, Pablo Díaz-Villoslada, Luis Brieva, Cecilia Borrás, Elisenda Grivé, Jaume Capellades, Xavier Montalban
American Journal of Neuroradiology Apr 2000, 21 (4) 702-706;
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