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Tsutomu Nakada
American Journal of Neuroradiology May 2000, 21 (5) 982;
Tsutomu Nakada
bProfessor and Chair Department of Integrated Neuroscience Brain Research Institute University of NiigataNiigata, Japan
M.D., Ph.D
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I believe that Dr. Jinkins is not aware of the fact that the presented images were T2-reversed (T2R) images as described in the Methods section where T2-weighted images are video-reversed. Perhaps he inadvertently believed that the images presented were T1-weighted and the structure had an intensity equivalent to that of fiber tracts. As you can immediately understand by examining the cortex, the structure that I identified as the indisium griseum (IG) had “gray matter” density. Unfortunately, reproduction of the fine images into a journal article often makes identification of contrast differences difficult. Nevertheless, I believe that one can identify the IG as gray matter in the presented T2R images. It is much more difficult, if not impossible, to identify the longitudinal striae (LS), which are fiber tracts, because these structures have intensity characteristics that are viturally identical to those of the corpus callosum. Nevertheless, LS can occasionally be distinguished as a structure adjacent to the IG, as in the case of Figure 1B (a small white matter structure next to the IG).

I hope that this explanation clears up the concerns of Dr. Jinkins.

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American Journal of Neuroradiology
Vol. 21, Issue 5
1 May 2000
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American Journal of Neuroradiology May 2000, 21 (5) 982;

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Tsutomu Nakada
American Journal of Neuroradiology May 2000, 21 (5) 982;
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