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Research ArticleBRAIN

Predictive Value of Lesions for Relapses in Relapsing-remitting Multiple Sclerosis

James A. Koziol, Simone Wagner, David F. Sobel, Lloyd S. Slivka, John S. Romine, Jack C. Sipe and Hans-Peter Adams
American Journal of Neuroradiology February 2001, 22 (2) 284-291;
James A. Koziol
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Simone Wagner
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David F. Sobel
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Lloyd S. Slivka
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John S. Romine
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Jack C. Sipe
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Hans-Peter Adams
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    fig 1.

    Summary operating characteristics and associated 95% confidence intervals for MR markers (OR combination) relative to the occurrence of subsequent relapse. Month denotes the number of months and MR images preceding the event time point. MR markers are combined across each of these time segments of months using the OR function. If the MR marker is present in any of the preceding months, the marker is set to 1; if absent in all months, the marker is set to 0

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    fig 2.

    Summary operating characteristics and associated 95% confidence intervals for MR markers (AND combination) relative to the occurrence of a subsequent relapse. Month denotes the number of months and MR images preceding the event. MR markers are combined across each of these time segments of months using the AND function. That is, if the MR marker is present in all of the preceding months, the marker is set to 1; if absent in any of the months, the marker is set to 0.

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    TABLE 1:

    Baseline demographic and clinical characteristics of 50 relapsing-remitting multiple sclerosis patients

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    TABLE 2:

    2 × 2 Contingency table and derived values for an individual patient

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    TABLE 3:

    Number of patients with exacerbations and MR markers by month in trial

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    TABLE 4:

    Operating characteristics of MR markers as predictors for exacerbations

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American Journal of Neuroradiology
Vol. 22, Issue 2
1 Feb 2001
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Cite this article
James A. Koziol, Simone Wagner, David F. Sobel, Lloyd S. Slivka, John S. Romine, Jack C. Sipe, Hans-Peter Adams
Predictive Value of Lesions for Relapses in Relapsing-remitting Multiple Sclerosis
American Journal of Neuroradiology Feb 2001, 22 (2) 284-291;

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Predictive Value of Lesions for Relapses in Relapsing-remitting Multiple Sclerosis
James A. Koziol, Simone Wagner, David F. Sobel, Lloyd S. Slivka, John S. Romine, Jack C. Sipe, Hans-Peter Adams
American Journal of Neuroradiology Feb 2001, 22 (2) 284-291;
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  • Optimal MRI Sequence for Identifying Occlusion Location in Acute Stroke: Which Value of Time-Resolved Contrast-Enhanced MRA?
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