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Research ArticleHEAD AND NECK

Reinterpretation of Cross-Sectional Images in Patients with Head and Neck Cancer in the Setting of a Multidisciplinary Cancer Center

Laurie A. Loevner, Adina I. Sonners, Brian J. Schulman, Kerstin Slawek, Randal S. Weber, David I. Rosenthal, Gul Moonis and Ara A. Chalian
American Journal of Neuroradiology November 2002, 23 (10) 1622-1626;
Laurie A. Loevner
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Adina I. Sonners
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Brian J. Schulman
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Kerstin Slawek
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Randal S. Weber
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David I. Rosenthal
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Gul Moonis
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Ara A. Chalian
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    Fig 1.

    57-year-old woman with a history of squamous cell carcinoma of the left side of the tongue. Enhanced CT image shows a necrotic regional nodal metastasis (arrows) in the contralateral neck that was detected on reinterpretation in the cancer center, but missed on the initial read. This was pathologically proved following neck dissection.

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    Fig 2.

    49-year-old woman with known cancer of the right side of the tongue and a second primary cancer of the nasopharynx detected at the time of image reinterpretation.

    A, Nonenhanced axial CT image shows asymmetry of the nasopharynx, with increased tissue on the left (arrow) and obliteration of the fat along the deep musculature (levator and tensor veli palatini muscles).

    B, Nonenhanced coronal CT image again shows increased tissue at the left nasopharynx (arrows). Subsequent biopsy revealed carcinoma.

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    Fig 3.

    80-year-old woman with primary pharyngeal cancer. A normal-sized, fat-replaced left jugulogastric lymph node was interpreted as abnormal because of inhomogeneous signal intensity.

    A, Axial nonenhanced T1-weighted (600/17/1 [repetition time/echo time/excitations]) MR image shows intrinsic high signal intensity in the lymph node (arrows) consistent with fat.

    B, Axial fat-suppressed T2-weighted (4000/80/1) MR image obtained at the same level as that in A shows hypointensity in the hilum of this node (arrow) consistent with suppressed fat.

Tables

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    TABLE 1:

    Categorized changes in image interpretation

    Type of ChangeNo. of Cases
    Nodal
     Missed pathologic nodes18
      Cervical14
      Retropharyngeal4
     Nodes misinterpreted as pathologic3
     Submandibular gland mistaken for nodes2
    Changes related to tumor extension
     Missed submucosal extension5
      Parapharyngeal3
      Preepiglottic2
     Presence or absence of cartilage invasion5
     Presence or absence of perineural spread4
     Underestimation of size or extent of tumor4
     Overestimation of size or extent of tumor3
    Changes related to primary neoplasm
     Primary cancer missed on imaging8
      Oral cavity6
      Pharynx2
     Normal anatomy mistaken for primary neoplasm3
    Missed second primary neoplasm6
    Missed metastasis2
    Missed middle cerebral artery aneurysm1
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    TABLE 2:

    Change in tumor staging and means of verification of the change in image interpretation

    Patient No.Change in TNMVerification of Change in InterpretationPatient No.Change in TNMVerification of Change in Interpretation
    1T ↑, N ↑Pathologic24T ↑Pathologic
    2T ↑Pathologic25N ↑Pathologic
    3T ↓, N ↓Pathologic26T ↑, N ↑Pathologic
    4T ↑Pathologic27N ↑Pathologic
    5T ↑Pathologic28T ↑Pathologic
    6N ↑Pathologic29T ↑Pathologic
    7N ↑Pathologic30N ↑Pathologic
    8T ↓Pathologic31N ↑Pathologic
    9T ↑, N ↑Pathologic32T ↑Pathologic
    10T ↑Pathologic33N ↑Pathologic
    11T ↑Pathologic34N ↑Radiologic
    12M ↑Pathologic35T ↑Radiologic
    13N ↓Pathologic36T ↑, N ↑Radiologic
    14T ↓Pathologic37N ↓Radiologic
    15T ↑Pathologic38T ↑, N ↑Radiologic
    16N ↑Pathologic39T ↓Radiologic
    17T ↓, N ↓Pathologic40N ↑Radiologic
    18T ↑Pathologic41M ↑Radiologic
    19N ↑Pathologic42N ↑Radiologic
    20N ↑Pathologic43N ↑Radiologic
    21T ↑Pathologic44N ↓Clinical/imaging
    22T ↑Pathologic45T ↑Clinical/imaging
    23T ↑, N ↓Pathologic46T ↑, N ↑Clinical/imaging
    • Note.—↑ indicates upstaged; ↓, downstaged; Radiologic, characteristic radiologic findings; Clinical/imaging, clinical and imaging follow-up.

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American Journal of Neuroradiology: 23 (10)
American Journal of Neuroradiology
Vol. 23, Issue 10
1 Nov 2002
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Cite this article
Laurie A. Loevner, Adina I. Sonners, Brian J. Schulman, Kerstin Slawek, Randal S. Weber, David I. Rosenthal, Gul Moonis, Ara A. Chalian
Reinterpretation of Cross-Sectional Images in Patients with Head and Neck Cancer in the Setting of a Multidisciplinary Cancer Center
American Journal of Neuroradiology Nov 2002, 23 (10) 1622-1626;

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Reinterpretation of Cross-Sectional Images in Patients with Head and Neck Cancer in the Setting of a Multidisciplinary Cancer Center
Laurie A. Loevner, Adina I. Sonners, Brian J. Schulman, Kerstin Slawek, Randal S. Weber, David I. Rosenthal, Gul Moonis, Ara A. Chalian
American Journal of Neuroradiology Nov 2002, 23 (10) 1622-1626;
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