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Research ArticleINTERVENTIONAL

Vein of Galen Aneurysmal Malformation: Diagnosis and Treatment of 13 Children with Extended Clinical Follow-up

Blaise V. Jones, William S. Ball, Thomas A. Tomsick, Justin Millard and Kerry R. Crone
American Journal of Neuroradiology November 2002, 23 (10) 1717-1724;
Blaise V. Jones
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William S. Ball
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Thomas A. Tomsick
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Justin Millard
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Kerry R. Crone
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    Fig 1.

    Images from the case of a 19-month-old patient with mild hydrocephalus and engorged scalp veins.

    A, Sagittal view T1-weighted MR image shows the markedly enlarged median prosencephalic vein of Markowski, characteristic of VGAM (arrow). Arterial feeders can be seen along the anterior wall of the vein.

    B, The complex arterial maze (arrows) is well seen on this conventional angiogram obtained with injection of the left vertebral artery. Coils can be seen along the right side of the varix, occluding several arterial feeders.

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    Fig 2.

    Images from the case of a 3-month-old triplet with worsening congestive heart failure.

    A, Volume-rendered MR angiogram shows, from an inferior prospective, the arterial feeders supplying the lesion from the left side (arrows).

    B, Carotid injection during arterial embolization procedure performed when the patient was 6 months old shows residual flow to the lesion from pericallosal and posterior choroidal arteries (arrowheads).

    C, Coronal view fast spin-echo T2-weighted MR image obtained 6 years after embolization shows continued patency of the varix and mild enlargement of extra-axial fluid spaces.

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    TABLE 1:

    Clinical presentation and outcomes of 13 children with vein of Galenaneurysmal malformation

    Patient No.Year of DiagnosisAge at DiagnosisSymptoms at DiagnosisLength of Follow-up (age)Outcome Score
    11987Neonate, full termCHF, hydrocephalusN/A0
    2198913 yearsHydrocephalus5 years (18 years)4
    31991Neonate, full termCHF9 years (9 years)4
    41992Neonate, pre-termCHF, hydrocephalusN/A0
    519935 monthsCHF, hydrocephalus2 years (2.5 years)4
    6199519 monthsMild CHF, hydrocephalus6.5 years (8 years)4
    71995Neonate, triplet, 1481Mild CHF6 years (6 years)4
    81996Neonate, twin, 32 weeks, gestationCHF3 months0
    91999Neonate, full termCHF18 months0
    101999Neonate, 37 weeks, gestationCHF24 months (2 years)1
    112000Neonate, 36 weeks, gestationCHFN/A0
    1220004 monthsHydrocephalus6 months (10 months)3
    1320014 monthsHydrocephalus19 months (2 years)3
    • Note.— CHF indicates congestive heart failure; N/A, not applicable.

    • View popup
    TABLE 2:

    Fistula classification, treatment variables, and outcomes for 13 children with vein of Galen aneurysmal malformation

    Patient No.Lesion ClassificationTreatmentShunted?Outcome Score
    1MuralArterial coils, venous coils, torcular approachN/A0
    2MuralArterial coils, arterial acrylicYes3
    3ChoroidalArterial coils, venous coils, arterial acrylicNo4
    4ChoroidalArterial coils, venous coilsN/A0
    5MuralArterial coilsYes4
    6Mixed (type III)Arterial coils, radiation therapyNo4
    7MuralArterial coils, venous coilsNo4
    8MuralArterial coils, venous approachN/A0
    9ChoroidalArterial coils, venous coilsYes0
    10ChoroidalArterial coils, venous coilsYes1
    11MuralArterial coilsN/A0
    12MuralArterial coilsYes3
    13ChoroidalArterial coilsYes3
    • Note.— N/A, not applicable.

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American Journal of Neuroradiology: 23 (10)
American Journal of Neuroradiology
Vol. 23, Issue 10
1 Nov 2002
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Cite this article
Blaise V. Jones, William S. Ball, Thomas A. Tomsick, Justin Millard, Kerry R. Crone
Vein of Galen Aneurysmal Malformation: Diagnosis and Treatment of 13 Children with Extended Clinical Follow-up
American Journal of Neuroradiology Nov 2002, 23 (10) 1717-1724;

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Vein of Galen Aneurysmal Malformation: Diagnosis and Treatment of 13 Children with Extended Clinical Follow-up
Blaise V. Jones, William S. Ball, Thomas A. Tomsick, Justin Millard, Kerry R. Crone
American Journal of Neuroradiology Nov 2002, 23 (10) 1717-1724;
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  • Management of Stroke in Infants and Children: A Scientific Statement From a Special Writing Group of the American Heart Association Stroke Council and the Council on Cardiovascular Disease in the Young
  • Vein of Galen Malformation: Prenatal Evaluation With Three-dimensional Power Doppler Angiography
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