Systemic Theophylline Augments the Blood Oxygen Level—Dependent Response to Forepaw Stimulation in Rats

References

1. ↵
   Malonek D, Dirnagel U, Lindauer U, Yamada K, Kanno I, Grinvald A. Vascular imprints of neural activity: relationships between the dynamics of cortical blood flow, oxygenation, and volume changes following sensory stimulation. Proc Natl Acad Sci U S A 1997;94:14826–14831

   Abstract/FREE Full Text
2. ↵
   Ogawa S, Menon RS, Tank DW, et al. Functional brain imaging by blood oxygenation level-dependent contrast magnetic resonance imaging. Biophys J 1993;64:803–812

   CrossRefPubMedWeb of Science
3. ↵
   Ogawa S, Lee TM, Kay AR, Tank DW. Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci U S A 1990;87:9868–9872

   Abstract/FREE Full Text
4. ↵
   Poulsen SA, Quinn RJ. Adenosine receptors: new opportunities for future drugs. Bioorg Med Chem 1998;6:619–641

   CrossRefPubMed
5. ↵
   Wahl M, Schilling L. Regulation of cerebral blood flow: a brief review. Acta Neurochir Suppl (Wien) 1993;59:3–10

   PubMed
6. ↵
   Morii S, Ngai AC, Ko KR, Winn HR. Role of adenosine in regulation of cerebral blood flow: effects of theophylline during normoxia and hypoxia. Am J Physiol 1987;253:H165–H175

   Abstract/FREE Full Text
7. ↵
   Ko KR, Ngai AC, Winn HR. Role of adenosine in regulation of regional cerebral blood flow in sensory cortex. Am J Physiol 1990;259:H1703–H1708

   Abstract/FREE Full Text
8. ↵
   Meno JR, Crum AV, Winn HR. Effect of adenosine receptor blockade on pial arteriolar dilation during sciatic nerve stimulation. Am J Physiol 2001 Nov;281:H2018–H2027

   Abstract/FREE Full Text
9. ↵
   Morii S, Ngai AC, Winn HR. Reactivity of rat pial arterioles and venules to adenosine and carbon dioxide: with detailed description of the closed cranial window technique in rats. J Cereb Blood Flow Metab 1986;6:34–41

   PubMedWeb of Science
10. ↵
    Hyder F, Behar KL, Martin MA, Blamire AM, Shulman RG. Dynamic magnetic resonance imaging of the rat brain during forepaw stimulation. J Cereb Blood Flow Metab 1994;14:649–655

    PubMedWeb of Science
11. ↵
    Morton DW, Maravilla KR, Meno JR, Winn HR. A clinically relevant rat model for testing BOLD fMRI techniques using single shot EPI at 1.5T. Radiology 2001;218:598–601

    PubMed
12. ↵
    Cohen JD, MacWhinney B, Flatt M, and Provost J. PsyScope: a new graphic interactive environment for designing psychology experiments. Behav Res Methods Instrum Comput 1993;25:257–271

    CrossRefWeb of Science
13. ↵
    Gyngell ML, Bock C, Schmitz B, Hoehn-Berlage M, Hossmann KA. Variation of functional MRI signal in response to frequency of somatosensory stimulation in alpha-chloralose anesthetized rats. Magn Reson Med 1996;36:13–15

    PubMedWeb of Science
14. Mandeville JB, Marota JJA, Kosofsky BE, et al. Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation. Magn Reson Med 1998;39:615–624

    PubMedWeb of Science
15. ↵
    Hsu EW, Hedlund LW, MacFall JR. Functional MRI of the rat somatosensory cortex: effects of hyperventilation. Magn Reson Med 1998;40:421–426

    PubMedWeb of Science
16. ↵
    Li J, Iadecola C. Nitric oxide and adenosine mediate vasodilatation during functional activation in cerebellar cortex. Neuropharmacology 1994;33:1453–1461

    CrossRefPubMedWeb of Science
17. ↵
    Dirnagl U, Niwa K, Lindauer U, Villringer A. Coupling of cerebral blood flow to neuronal activation: role of adenosine and nitric oxide. Am J Physiol 1994;267:H296–H301

    Abstract/FREE Full Text
18. ↵
    Kastrup A, Li TQ, Takahashi A, Glover GH, Moseley ME. Functional magnetic resonance imaging of cerebral blood oxygenation changes during breath holding. Stroke 1998;29:2641–2645

    Abstract/FREE Full Text
19. Rostrup E, Larsson HB, Toft PB, et al. Functional MRI of CO2 induced increases in cerebral perfusion. NMR Biomed 1994;7:29–34

    PubMedWeb of Science
20. Rostrup E, Law I, Blinkenberg M, et al. Regional differences in the CBF and BOLD responses to hypercapnia: a combined PET and fMRI study. Neuroimage 2000;11:87–97

    CrossRefPubMedWeb of Science
21. ↵
    Graham GD, Zhong J, Petroff OA, Constable RT, Prichard JW, Gore JC. BOLD MRI monitoring of changes in cerebral perfusion induced by acetazolamide and hypercarbia in the rat. Magn Reson Med 1994;3:557–560
22. ↵
    Phillis JW, Delong RE. An involvement of adenosine in cerebral blood flow regulation during hypercapnia. Gen Pharmacol 1987;18:133–139

    CrossRefPubMed
23. ↵
    Estevez AY, Phillis JW. Hypercapnia-induced increases in cerebral blood flow: roles of adenosine, nitric oxide and cortical arousal. Brain Res 1997;758:1–8

    CrossRefPubMedWeb of Science
24. ↵
    Hedera P, Lai S, Lewin JS, et al. Assessment of cerebral blood flow reserve using functional magnetic resonance imaging. J Magn Reson Imaging 1996;6:718–725

    PubMed
25. ↵
    Bruhn H, Kleinschmidt A, Boecker H, Merboldt KD, Hanicke W, Frahm J. The effect of acetazolamide on regional cerebral blood oxygenation at rest and under stimulation as assessed by MRI. J Cereb Blood Flow Metab 1994;742–748
26. ↵
    Hyder F, Shulman RG, Rothman DL, Behar KL. Localized energetic changes with brain activation from anesthesia: absolute CBF changes at 7 tesla. In: Eighth Scientific Meeting and Exhibition: Book of Abstracts. Berkeley, Calif: International Society for Magnetic Resonance in Medicine;2000 :8:444
27. ↵
    Graham GD, Zhong J, Petroff OA, Constable RT, Prichard JW, Gore JC. BOLD MRI monitoring of changes in cerebral perfusion induced by acetazolamide and hypercarbia in the rat. Magn Reson Med 1994;31:557–560

    PubMed
28. Hoge RD, Atkinson J, Gill B, Crelier GR, Marrett S, Pike GB. Investigation of BOLD signal dependence on cerebral blood flow and oxygen consumption: the deoxyhemoglobin dilution model. Magn Reson Med 1999;42:849–863

    CrossRefPubMedWeb of Science
29. Kastrup A, Kruger G, Glover GH, Neumann-Haefelin T, Moseley ME. Regional variability of cerebral blood oxygenation response to hypercapnia. Neuroimage 1999;10:675–681

    CrossRefPubMedWeb of Science
30. ↵
    Rostrup E, Law I, Blinkenberg M, et al. Regional differences in the CBF and BOLD responses to hypercapnia: a combined PET and fMRI study. Neuroimage 2000;11:87–97
31. ↵
    Li TQ, Kastrup A, Mosley ME, Glover GH. Changes in baseline cerebral blood flow in humans do not influence regional cerebral blood flow response to photic stimulation. J Magn Reson Med 2000;12:757–762
32. ↵
    Hsu EW, Hedlund LW, MacFall JR. Functional MRI of the rat somatosensory cortex: effects of hyperventilation. Magn Reson Med 1998;40:421–426
33. ↵
    Weckesser M, Posse S, Olthoff U, Kemna L, Dager S, Muller-Gartner HW. Functional imaging of the visual cortex with bold-contrast MRI: hyperventilation decreases signal response. Magn Reson Med 1999;41:213–216

    CrossRefPubMedWeb of Science
34. ↵
    Phillis JW, Edstrom JP, Kostopoulos GK, Kirkpatrick JR. Effects of adenosine and adenine nucleotides on synaptic transmission in the cerebral cortex. Can J Physiol Pharmacol 1979;57:1289–1312

    PubMedWeb of Science
35. ↵
    Rees G, Friston K, Koch C. A direct quantitative relationship between the functional properties of human and macaque V5. Nature Neurosci 2000;3:716–723

    CrossRefPubMedWeb of Science