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Research ArticleINTERVENTIONAL

Study of the Patency of Small Arterial Branches after Stent Placement with an Experimental in Vivo Model

Osamu Masuo, Tomoaki Terada, Gary Walker, Mitsuharu Tsuura, Hiroyuki Matsumoto, Kazuo Tohya, Michio Kimura, Kunio Nakai and Toru Itakura
American Journal of Neuroradiology April 2002, 23 (4) 706-710;
Osamu Masuo
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Tomoaki Terada
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Gary Walker
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Mitsuharu Tsuura
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Hiroyuki Matsumoto
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Kazuo Tohya
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Michio Kimura
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Kunio Nakai
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Toru Itakura
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    Fig 1.

    Representative case (case 4).

    A, Diameter of abdominal aorta is measured by using a measure wire.

    B, Angiography is performed before stenting.

    C, Just after stenting, angiography is performed to evaluate the patency of the lumbar artery (arrow).

    D, Follow-up angiogram, obtained 3 months after stenting, confirms that the lumbar artery remains patent (arrow).

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    Fig 2.

    Case 5. Scanning electron microscopic findings obtained 1 week after stenting for the rabbit that became paraparetic after stenting reveal that the lumbar artery (asterisk) in the stent is patent without thrombus. The diameter of the lumbar artery is 729 μm. Endothelial integrity is injured along the struts by stent expansion (arrows), and underlying smooth muscle fiber is exposed in part of the luminal surface because of post-processing (original magnification ×100).

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    Fig 3.

    Representative case (case 4). Scanning electron microscopic findings obtained 3 months after stent placement reveal an open ostium of the lumbar artery (asterisk) and also show that regenerated endothelial-like cells are covered with stent strut in contact with the aorta and extend to the struts crossing the ostium of the lumbar artery (arrows). In this case, the extension of the regenerated endothelial cells into the ostia of lumbar arteries was observed (arrow), although the degree of narrowing due to this extension was not significant.

    A, Original magnification ×80.

    B, Original magnification ×150.

  • Fig 4.
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    Fig 4.

    Microscopic findings stained with hematoxylin and eosin reveal that the luminal surface of the struts (S) across the ostium of the lumbar artery (asterisk) is lined with a monolayer of cells resembling regenerative endothelial cells.

    A, Original magnification ×200.

    B, Original magnification ×400.

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    TABLE

    Summary of cases

    RabbitDiameter of Aorta (mm)Diameter of Lumbar Artery (μm)Deployed Stent Diameter (mm)Stent-to-Artery RatioAngiographic ComplicationPatency of Lumbar Artery
    Just After3 Months After
    12.86723.081.10NonePatentPatent
    23.14733.521.14NonePatentPatent
    32.83.331.19Dissection*
    42.38023.321.44NonePatentPatent
    52.67293.321.28None†PatentPatent‡
    63.25593.521.10NonePatentPatent
    73.26203.521.10NonePatentPatent
    83.33.521.07NonePatentPatent
    Average2.96433.391.17
    • * In this case, the stent was delivered without a guidewire and caused intimal dissection.

    • † This rabbit became paraparetic after stenting, although the lumbar artery was patent on the post-stenting angiogram.

    • ‡ Follow-up angiography of the rabbit was performed 1 week after stenting.

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American Journal of Neuroradiology: 23 (4)
American Journal of Neuroradiology
Vol. 23, Issue 4
1 Apr 2002
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Cite this article
Osamu Masuo, Tomoaki Terada, Gary Walker, Mitsuharu Tsuura, Hiroyuki Matsumoto, Kazuo Tohya, Michio Kimura, Kunio Nakai, Toru Itakura
Study of the Patency of Small Arterial Branches after Stent Placement with an Experimental in Vivo Model
American Journal of Neuroradiology Apr 2002, 23 (4) 706-710;

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Study of the Patency of Small Arterial Branches after Stent Placement with an Experimental in Vivo Model
Osamu Masuo, Tomoaki Terada, Gary Walker, Mitsuharu Tsuura, Hiroyuki Matsumoto, Kazuo Tohya, Michio Kimura, Kunio Nakai, Toru Itakura
American Journal of Neuroradiology Apr 2002, 23 (4) 706-710;
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