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Research ArticleBRAIN

Subtraction Helical CT Angiography of Intra- and Extracranial Vessels

Technical Considerations and Preliminary Experience

Vijayam K. Jayakrishnan, Philip M. White, Douglas Aitken, Paul Crane, Alex D. McMahon and Evelyn M. Teasdale
American Journal of Neuroradiology March 2003, 24 (3) 451-455;
Vijayam K. Jayakrishnan
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Philip M. White
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Douglas Aitken
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Paul Crane
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Alex D. McMahon
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Evelyn M. Teasdale
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Article Figures & Data

Figures

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  • Fig 1.
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    Fig 1.

    Image processing for subtraction CTA.

    A, Three-dimensional model of the skull is created from precontrast dataset.

    B, MIP created from the contrast-enhanced dataset.

    C, Subtracted image after removing A from B, before any editing.

    D, Subtracted image with minimal editing.

  • Fig 2.
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    Fig 2.

    The restraining device is molded around the back of the patient’s head and the angles of the jaw. Inset shows the valve for the suction connection

  • Fig 3.
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    Fig 3.

    MIP images.

    A, MIP CTA image after editing shows residual bone at the base of the skull.

    B, MIP DSCTA image better shows the basilar artery, its branches. and the aneurysm.

  • Fig 4.
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    Fig 4.

    MIP images.

    A, MIP CTA image shows that bone obscures the detail of the distal vertebral arteries.

    B, MIP DSCTA image clearly shows clear the vertebral arteries and the posterior inferior cerebellar arteries.

Tables

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    TABLE 1:

    Patient selection

    Indications for CTA and DSCTANo. of Patients (n = 30)
    Suspected or known intracranial aneurysm14
    Carotid occlusive disease10
    Skull-base tumors3
    Cerebral venous thrombosis3
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    TABLE 2:

    Grading system used for the assessment of image quality

    Grade and DefinitionIntracranial FindingsNeck Findings
    Circle of WillisSkull-Base VesselsCarotidsVertebral Arteries
    1, nondiagnosticObscuredObscuredObscuredObscured
    2, poor qualityPoorly visualizedObscuredPoorly visualizedObscured
    3, acceptableClearly seenObscuredClearly seenObscured
    4, good qualityClearly seenPartly obscuredClearly seenPartly obscured
    5, excellentClearly seenClearly seenClearly seenClearly seen
    • View popup
    TABLE 3:

    Summary of quality scores for images produced with CTA and DSCTA

    TestOperator 1 (n = 30)Operator 2 (n = 30)
    MeanMedianSDMeanMedianSD
    CTA2.5030.862.6730.80
    Hard-copy check by operator 33.0731.172.8331.09
    DSCTA3.3730.813.3030.95
    Hard copy check by operator 33.9740.853.8340.95
    DSCTA minus CTA*0.8710.730.6310.56
    Hard-copy check by Observer 3†0.9011.031.0011.11
    • * 95% CIs were 0.59, 1.14 for operator 1 and 0.43, 0.84 for operator 2. P values with the t test were <.001 for both operators.

    • † 95% CIs were 0.52, 1.25 for operator 1 and 0.58, 1.42 for operator 2. P values with the t test were <.001 for both operators.

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    TABLE 4:

    Comparison of the time to assess the images produced with CTA and DSCTA

    Observer (n = 30)CTADSCTACTA vs DSCTA
    MeanSDMeanSDMean95% CIP Value
    18.442.478.882.89−0.44−1.19, 0.32.249
    210.074.557.532.852.531.08, 3.99.001
    1 and 2 (mean)9.263.108.212.251.050.34, 1.75.005
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American Journal of Neuroradiology: 24 (3)
American Journal of Neuroradiology
Vol. 24, Issue 3
1 Mar 2003
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Cite this article
Vijayam K. Jayakrishnan, Philip M. White, Douglas Aitken, Paul Crane, Alex D. McMahon, Evelyn M. Teasdale
Subtraction Helical CT Angiography of Intra- and Extracranial Vessels
American Journal of Neuroradiology Mar 2003, 24 (3) 451-455;

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Subtraction Helical CT Angiography of Intra- and Extracranial Vessels
Vijayam K. Jayakrishnan, Philip M. White, Douglas Aitken, Paul Crane, Alex D. McMahon, Evelyn M. Teasdale
American Journal of Neuroradiology Mar 2003, 24 (3) 451-455;
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