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Research ArticleBRAIN

Diffusion-Weighted Imaging in the Follow-up of Treated High-Grade Gliomas: Tumor Recurrence versus Radiation Injury

Patrick A. Hein, Clifford J. Eskey, Jeffrey F. Dunn and Eugen B. Hug
American Journal of Neuroradiology February 2004, 25 (2) 201-209;
Patrick A. Hein
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Clifford J. Eskey
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Jeffrey F. Dunn
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Eugen B. Hug
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References

  1. ↵
    Samnick S, Bader JB, Hellwig D, et al. Clinical value of iodine-123-alpha-methyl-L-tyrosine single-photon emission tomography in the differential diagnosis of recurrent brain tumor in patients pretreated for glioma at follow-up. J Clin Oncol 2002;20:396–404
    Abstract/FREE Full Text
  2. ↵
    Langleben DD, Segall GM. PET in differentiation of recurrent brain tumor from radiation injury. J Nucl Med 2000;41:1861–1867
    Abstract/FREE Full Text
  3. Schlemmer HP, Bachert P, Henze M, et al. Differentiation of radiation necrosis from tumor progression using proton magnetic resonance spectroscopy. Neuroradiology 2002;44:216–222
    CrossRefPubMedWeb of Science
  4. ↵
    Sugahara T, Korogi Y, Tomiguchi S, et al. Posttherapeutic intraaxial brain tumor: the value of perfusion-sensitive contrast-enhanced MR imaging for differentiating tumor recurrence from nonneoplastic contrast-enhancing tissue. AJNR Am J Neuroradiology 2000;21:901–909
    Abstract/FREE Full Text
  5. ↵
    Kumar AJ, Leeds NE, Fuller GN, et al. Malignant gliomas: MR imaging spectrum of radiation therapy- and chemotherapy-induced necrosis of the brain after treatment. Radiology 2000;217:377–384
    CrossRefPubMedWeb of Science
  6. ↵
    Brunberg JA, Chenevert TL, McKeever PE, et al. In vivo MR determination of water diffusion coefficients and diffusion anisotropy: correlation with structural alteration in gliomas of the cerebral hemispheres. AJNR Am J Neuroradiol 1995;16:361–371
    Abstract/FREE Full Text
  7. ↵
    Castillo M, Smith JK, Kwock L, Wilber K. Apparent diffusion coefficients in the evaluation of high-grade cerebral gliomas. AJNR Am J Neuroradiol 2001;22:60–64
    Abstract/FREE Full Text
  8. ↵
    Lam WW, Poon WS, Metreweli C. Diffusion MR imaging in glioma: does it have any role in the pre-operation determination of grading of glioma? Clin Radiol 2002;57:219–225
    CrossRefPubMed
  9. ↵
    Kono K, Inoue Y, Nakayama K, et al. The role of diffusion-weighted imaging in patients with brain tumors. AJNR Am J Neuroradiol 2001;22:1081–1088
    Abstract/FREE Full Text
  10. ↵
    Tsui EY, Chan JH, Ramsey RG, et al. Late temporal lobe necrosis in patients with nasopharyngeal carcinoma: evaluation with combined multi-section diffusion weighted and perfusion weighted MR imaging. Eur J Radiol 2001;39:133–138
    PubMed
  11. ↵
    Sugahara T, Korogi Y, Kochi M, et al. Usefulness of diffusion-weighted imaging with echo-planar technique in the evaluation of cellularity in gliomas, J Magn Reson Imaging 1999;9:53–60
    CrossRefPubMedWeb of Science
  12. ↵
    Krabbe K, Gideon P, Wagn P, Hansen U, Thomsen C, Madsen F. MR diffusion imaging of human intracranial tumours. Neuroradiology 1997;39:483–489
    CrossRefPubMed
  13. ↵
    Guo AC, Cummings TJ, Dash RC, Provenzale JM. Lymphomas and high-grade astrocytomas: comparison of water diffusibility and histologic characteristics. Radiology 2002;224:177–183
    CrossRefPubMedWeb of Science
  14. ↵
    Cha S, Knopp EA, Johnson G, et al. Dynamic contrast-enhanced T2-weighted MR imaging of recurrent malignant gliomas treated with thalidomide and carboplatin. AJNR Am J Neuroradiol 2000;21:881–890
    Abstract/FREE Full Text
  15. ↵
    Schlemmer HP, Bachert P, Herfarth KK, Zuna I, Debus J, van Kaick G. Proton MR spectroscopic evaluation of suspicious brain lesions after stereotactic radiotherapy. AJNR Am J Neuroradiol 2001;22:1316–1324
    Abstract/FREE Full Text
  16. ↵
    Graves EE, Nelson SJ, Vigneron DB, et al. Serial proton MR spectroscopic imaging of recurrent malignant gliomas after gamma knife radiosurgery. AJNR Am J Neuroradiol 2001;22:613–624
    Abstract/FREE Full Text
  17. Traber F, Block W, Flacke S, et al. 1H-MR spectroscopy of brain tumors in the course of radiation therapy: use of fast spectroscopic imaging and single-voxel spectroscopy for diagnosing recurrence. Fortschr Röntgenstr 2002;174:33–42
  18. ↵
    Chong VF, Rumpel H, Fan YF, Mukherji SK. Temporal lobe changes following radiation therapy: imaging and proton MR spectroscopic findings. Eur Radiol 2001;11:317–324
    CrossRefPubMed
  19. ↵
    Chao ST, Suh JH, Raja S, Lee SY, Barnett G. The sensitivity and specificity of FDG PET in distinguishing recurrent brain tumor from radionecrosis in patients treated with stereotactic radiosurgery. Int J Cancer 2001;96:191–197
    CrossRefPubMedWeb of Science
  20. ↵
    Chung JK, Kim YK, Kim SK, et al. Usefulness of 11C-methionine PET in the evaluation of brain lesions that are hypo- or isometabolic on 18F-FDG PET. Eur J Nucl Med Mol Imaging 2002;29:176–182
    CrossRefPubMed
  21. ↵
    Stokkel M, Stevens H, Taphoom M, Van Rijk PP. Differentiation between recurrent brain tumor and post-radiation necrosis: the value of 201T1 SPET versus 18F-FDG PET using dual headed coincidence camera—a pilot study. Nucl Med Commun 1999;20:411–417
    PubMed
  22. ↵
    Weber W, Bartenstein P, Gross MW, et al. Fluorine-18-FDG PET and iodine 123-IMT-SPECT in the evaluation of brain tumors. J Nucl Med 1997;38:802–808
    Abstract/FREE Full Text
  23. Sonoda Y, Kumabe T, Takahashi T, Shirane R, Yoshimoto T. Clinical usefulness of 11C-MET PET and 201T1 SPECT for differentiation of recurrent glioma from radiation necrosis. Neurol Med Chir 1998;38:342–347
    CrossRef
  24. ↵
    Thompson TP, Lunsford LD, Kondziolka D. Distinguishing recurrent tumor and radiation necrosis with positron emission tomography versus stereotactic biopsy. Stereotact Funct Neurosurg 1999;73:9–14
    CrossRefPubMed
  25. ↵
    Mullins ME, Schaefer PW, Sorensen AG, et al. CT and conventional and diffusion-weighted MR imaging in acute stroke: study in 691 patients at presentation to the emergency department. Radiology 2002;224:353–360
    PubMedWeb of Science
  26. ↵
    Schaefer PW, Ozsunar Y, He J, et al. Assessing tissue viability with MR diffusion and perfusion imaging. AJNR Am J Neuroradiol 2003;24:436–443
    Abstract/FREE Full Text
  27. ↵
    Stadnik TW, Chaskis C, Michotte A, et al. Diffusion-weighted MR imaging of intracerebral masses: comparison with conventional MR imaging and histologic findings. AJNR Am J Neuroradiol 2001;22:969–976
    Abstract/FREE Full Text
  28. ↵
    Park SH, Chang KH, Song IC, Kim YJ, Kim SH, Han MH. Diffusion-weighted MRI in cystic and necrotic intracranial lesions. Neuroradiology 2000;42:716–721
    CrossRefPubMed
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American Journal of Neuroradiology: 25 (2)
American Journal of Neuroradiology
Vol. 25, Issue 2
1 Feb 2004
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Cite this article
Patrick A. Hein, Clifford J. Eskey, Jeffrey F. Dunn, Eugen B. Hug
Diffusion-Weighted Imaging in the Follow-up of Treated High-Grade Gliomas: Tumor Recurrence versus Radiation Injury
American Journal of Neuroradiology Feb 2004, 25 (2) 201-209;

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Diffusion-Weighted Imaging in the Follow-up of Treated High-Grade Gliomas: Tumor Recurrence versus Radiation Injury
Patrick A. Hein, Clifford J. Eskey, Jeffrey F. Dunn, Eugen B. Hug
American Journal of Neuroradiology Feb 2004, 25 (2) 201-209;
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  • Centrally Reduced Diffusion Sign for Differentiation between Treatment-Related Lesions and Glioma Progression: A Validation Study
  • Quantitation of brain tumour microstructure response to Temozolomide therapy using non-invasive VERDICT MRI
  • Sequential Apparent Diffusion Coefficient for Assessment of Tumor Progression in Patients with Low-Grade Glioma
  • MRI with DWI for the Detection of Posttreatment Head and Neck Squamous Cell Carcinoma: Why Morphologic MRI Criteria Matter
  • Diagnostic Accuracy of Centrally Restricted Diffusion in the Differentiation of Treatment-Related Necrosis from Tumor Recurrence in High-Grade Gliomas
  • Differentiation between Radiation Necrosis and Tumor Progression Using Chemical Exchange Saturation Transfer
  • Although Non-diagnostic Between Necrosis and Recurrence, FDG PET/CT Assists Management of Brain Tumours After Radiosurgery
  • Independent Poor Prognostic Factors for True Progression after Radiation Therapy and Concomitant Temozolomide in Patients with Glioblastoma: Subependymal Enhancement and Low ADC Value
  • Diffusion and Perfusion MRI to Differentiate Treatment-Related Changes Including Pseudoprogression from Recurrent Tumors in High-Grade Gliomas with Histopathologic Evidence
  • Imaging biomarkers of angiogenesis and the microvascular environment in cerebral tumours
  • Clinical applications of imaging biomarkers. Part 3. The neuro-oncologist's perspective
  • Distinguishing Recurrent Primary Brain Tumor from Radiation Injury: A Preliminary Study Using a Susceptibility-Weighted MR Imaging-Guided Apparent Diffusion Coefficient Analysis Strategy
  • Apparent Diffusion Coefficient of Glial Neoplasms: Correlation with Fluorodeoxyglucose-Positron-Emission Tomography and Gadolinium-Enhanced MR Imaging
  • MR Spectroscopy in Radiation Injury
  • Closing the Uncertainty Gap in the Diagnosis of Parotid Tumors
  • Distinguishing Recurrent Intra-Axial Metastatic Tumor from Radiation Necrosis Following Gamma Knife Radiosurgery Using Dynamic Susceptibility-Weighted Contrast-Enhanced Perfusion MR Imaging
  • Usefulness of diffusion/perfusion-weighted MRI in patients with non-enhancing supratentorial brain gliomas: a valuable tool to predict tumour grading?
  • Evaluation of the larynx for tumour recurrence by diffusion-weighted MRI after radiotherapy: initial experience in four cases
  • Diagnosis and Treatment of Recurrent High-Grade Astrocytoma
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