Article Figures & Data
Figures
- Fig 1.
Rabbit angiograms.
A, Baseline measurements. B, During vasospasm. C, Following IA nimodipine treatment. Insets show enlarged portions of the corresponding angiograms. Measured diameters are given as transecting lines.
- Fig 2.
Changes in vertebral artery diameters in different treatment groups. Values are obtained from five experiments. Asterisk indicates a value that is statistically significant from spasm values (P < .05).
- Fig 3.
Changes in basilar artery diameters in different treatment groups. Values are obtained from five experiments. Asterisk indicates a value that is statistically significant from spasm values (P < .05).
Tables
Treatment groups Baseline (mm) Vasospasm (mm) Treatment (mm) ia nimodipine 0.63 ± 0.04 0.41 ± 0.03* 0.61 ± 0.03†§ it nimodipine 0.69 ± 0.04 0.40 ± 0.08* 0.55 ± 0.55† ia vehicle 0.55 ± 0.03 0.38 ± 0.02* 0.39 ± 0.02 it vehicle 0.52 ± 0.04 0.40 ± 0.05* 0.36 ± 0.07 ia papaverine 0.51 ± 0.02 0.35 ± 0.01* 0.44 ± 0.03† All values were derived from n=5 experiments except for IT vehicle group, where n=2 experiments were applied.
* Statistically significant from baseline values (P < .05).
† Statistically significant from values obtained at vasospasm (P < .05).
§ Statistically significant from values obtained in IA papaverine treatment.
Treatment groups Baseline (mm) Vasospasm (mm) Treatment (mm) ia nimodipine 0.70 ± 0.03 0.40 ± 0.06* 0.62 ± 0.02†§ it nimodipine 0.83 ± 0.03 0.42 ± 0.06* 0.51 ± 0.06† ia vehicle 0.67 ± 0.02 0.48 ± 0.01* 0.48 ± 0.01 it vehicle 0.59 ± 0.01 0.47 ± 0.01* 0.41 ± 0.05 ia papaverine 0.60 ± 0.02 0.43 ± 0.03* 0.49 ± 0.03† All values were derived from n=5 experiments except for IT vehicle group where n=2 experiments were applied. Data were expressed as mean ± SEM.
* Statistically significant from baseline values (P < .05).
† Statistically significant from values obtained during vasospasm (P < .05).
§ Statistically significant from values obtained in either IT nimodipine or IA papaverine treatments.
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