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Research ArticlePEDIATRICS

Cerebral Proton Magnetic Resonance Spectroscopy in Children with Diabetic Ketoacidosis

S.L. Wootton-Gorges, M.H. Buonocore, N. Kuppermann, J.P. Marcin, P.D. Barnes, E.K. Neely, J. DiCarlo, T. McCarthy and N.S. Glaser
American Journal of Neuroradiology May 2007, 28 (5) 895-899;
S.L. Wootton-Gorges
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M.H. Buonocore
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N. Kuppermann
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J.P. Marcin
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P.D. Barnes
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E.K. Neely
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J. DiCarlo
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T. McCarthy
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N.S. Glaser
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    Fig 1.

    A 13-year-old girl with insulin-dependent diabetes mellitus. Spectra from the right basal ganglia during DKA episode and after recovery, demonstrating a lower NAA/Cr ratio during DKA.

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    Fig 2.

    Relative (A) NAA/Cr and (B) Cho/Cr in the basal ganglia, occipital gray matter, and periaqueductal gray matter in study patients during DKA episode and after recovery.

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American Journal of Neuroradiology: 28 (5)
American Journal of Neuroradiology
Vol. 28, Issue 5
May 2007
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S.L. Wootton-Gorges, M.H. Buonocore, N. Kuppermann, J.P. Marcin, P.D. Barnes, E.K. Neely, J. DiCarlo, T. McCarthy, N.S. Glaser
Cerebral Proton Magnetic Resonance Spectroscopy in Children with Diabetic Ketoacidosis
American Journal of Neuroradiology May 2007, 28 (5) 895-899;

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Cerebral Proton Magnetic Resonance Spectroscopy in Children with Diabetic Ketoacidosis
S.L. Wootton-Gorges, M.H. Buonocore, N. Kuppermann, J.P. Marcin, P.D. Barnes, E.K. Neely, J. DiCarlo, T. McCarthy, N.S. Glaser
American Journal of Neuroradiology May 2007, 28 (5) 895-899;
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Cited By...

  • Exploratory Multisite Magnetic Resonance Spectroscopic Imaging Shows White Matter Neuroaxonal Loss Associated with Complications of Type 1 Diabetes in Children
  • Acute and chronic neuroinflammation is triggered by diabetic ketoacidosis in a rat model
  • Cognitive Function Following Diabetic Ketoacidosis in Children With New-Onset or Previously Diagnosed Type 1 Diabetes
  • Altered brain metabolites in patients with diabetes mellitus and related complications - evidence from 1H MRS study
  • Neurological Consequences of Diabetic Ketoacidosis at Initial Presentation of Type 1 Diabetes in a Prospective Cohort Study of Children
  • Progressive Decrease in N-Acetylaspartate/Creatine Ratio in a Teenager with Type 1 Diabetes and Repeated Episodes of Ketoacidosis without Clinically Apparent Cerebral Edema: Evidence for Permanent Brain Injury
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