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Research ArticleBRAIN

Phase-Contrast MR Imaging Support for the Diagnosis of Aqueductal Stenosis

S. Stoquart-El Sankari, P. Lehmann, C. Gondry-Jouet, A. Fichten, O. Godefroy, M.-E. Meyer and O. Baledent
American Journal of Neuroradiology January 2009, 30 (1) 209-214; DOI: https://doi.org/10.3174/ajnr.A1308
S. Stoquart-El Sankari
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P. Lehmann
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C. Gondry-Jouet
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A. Fichten
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O. Godefroy
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M.-E. Meyer
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O. Baledent
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    Fig 1.

    Sagittal scout view sequences are used as localizers to select the anatomic levels for flow quantification. The acquisition planes are selected perpendicular to the presumed direction of the flow. Sections through the C2–C3 subarachnoid space level (a), fourth ventricle (b), and Sylvian aqueduct (c) are used for CSF. By varying the velocity encoding, the same cervical section level (a) is used to measure vascular flows in the left and right internal carotid arteries, vertebral arteries, and internal jugular veins.

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    Fig 2.

    Sagittal T2 conventional MR image in a 50-year-old patient admitted for recent gait and urinary dysfunction, with a medical history of chronic headaches. Note the dilated lateral and 3rd Vs associated with a comparatively small 4th V. There is a slight downward bulging of the floor of the 3rd V, but no direct signs of obstruction at the aqueductal level. PC-MR imaging (not shown) showed a total absence of CSF flow at the aqueductal level and helped the neurosurgeon with the diagnosis of aqueductal stenosis.

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    Table 1:

    Clinical presentation in patients with AS

    SymptomsAcute Onset*Subacute Onset†Chronic Onset‡
    Headache541
    Gait disturbance016
    Memory disturbance016
    Incontinence015
    Seizure020
    • Note:—AS indicates aqueductal stenosis.

    • * Duration between symptoms and radiologic examination <1 month.

    • † Duration between 1 and 6 months.

    • ‡ Chronic onset: duration >6 months. Numbers refer to patients in each category.

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    Table 2:

    Morphologic MR imaging results*

    PresentAbsentUnknown
    Triventricular dilation1700
    Small/normal 4th V1700
    Direct CSF pathway obstruction (sagittal T2)1043
    Downward bulging of the floor of the 3rd V1070
    Space-occupying lesion3140
    • Note:—4th V indicates fourth ventricle; 3rd V, third ventricle.

    • * Numbers refer to the patients in each category.

    • View popup
    Table 3:

    Amplitude and temporal parameters of vascular blood flow and CSF (cervical and ventricular) flows in patients with AS and controls*

    ASControlP
    No. of patients1720NS
    Age (yr)3944NS
    Vascular flows
        Arterial mean flow (mL/min)589 ± 115607 ± 158NS
        Venous mean flow (mL/min)379 ± 157417 ± 158NS
        Arteriovenous delay (% of CC)16 ± 1219 ± 12NS
        Arteriovenous stroke volume (mL)0.8 ± 0.20.8 ± 0.3NS
    Cervical flows
        C2–C3 peak flush flow (mL/min)157 ± 58160 ± 54NS
        C2–C3 peak flush latency (% of CC)6 ± 35 ± 4NS
        C2–C3 stroke volume (μL/CC)499 ± 251508 ± 166NS
    4th V flows
        4th V peak flush latency (% CC)4 ± 713 ± 8.05
        4th V stroke volume (μL/CC)24 ± 1824 ± 13NS
    Aqueductal level
        Stroke volume (μL/CC)∅44 ± 25
    • Note:—NS indicates no significance;∅, absence of flow.

    • * Results are represented by mean ± SD values.

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American Journal of Neuroradiology: 30 (1)
American Journal of Neuroradiology
Vol. 30, Issue 1
January 2009
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Cite this article
S. Stoquart-El Sankari, P. Lehmann, C. Gondry-Jouet, A. Fichten, O. Godefroy, M.-E. Meyer, O. Baledent
Phase-Contrast MR Imaging Support for the Diagnosis of Aqueductal Stenosis
American Journal of Neuroradiology Jan 2009, 30 (1) 209-214; DOI: 10.3174/ajnr.A1308

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Phase-Contrast MR Imaging Support for the Diagnosis of Aqueductal Stenosis
S. Stoquart-El Sankari, P. Lehmann, C. Gondry-Jouet, A. Fichten, O. Godefroy, M.-E. Meyer, O. Baledent
American Journal of Neuroradiology Jan 2009, 30 (1) 209-214; DOI: 10.3174/ajnr.A1308
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