Research ArticleBRAIN
Does Diffusion-Weighted Imaging Represent the Ischemic Core? An Evidence-Based Systematic Review
P.G. Kranz and J.D. Eastwood
American Journal of Neuroradiology June 2009, 30 (6) 1206-1212; DOI: https://doi.org/10.3174/ajnr.A1547
Article Information
vol. 30 no. 6 1206-1212
PubMed
Published By
Print ISSN
Online ISSN
History
- Received October 21, 2008
- Accepted after revision January 22, 2009
- Published online June 11, 2009.
Article Versions
- Latest version (April 8, 2009 - 12:55).
- You are viewing the most recent version of this article.
Copyright & Usage
Copyright © American Society of Neuroradiology
Author Information
Altmetrics
Cited By...
This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.
- The Infarct Core is Well Represented by the Acute Diffusion Lesion: Sustained Reversal is InfrequentBruce CV Campbell, Archana Purushotham, Soren Christensen, Patricia M Desmond, Yoshinari Nagakane, Mark W Parsons, Maarten G Lansberg, Michael Mlynash, Matus Straka, Deidre A De Silva, Jean-Marc Olivot, Roland Bammer, Gregory W Albers, Geoffrey A Donnan, Stephen M DavisJournal of Cerebral Blood Flow & Metabolism 2012 32 1
- Archana Purushotham, Bruce C. V. Campbell, Matus Straka, Michael Mlynash, Jean-Marc Olivot, Roland Bammer, Stephanie M. Kemp, Gregory W. Albers, Maarten G. LansbergInternational Journal of Stroke 2015 10 3
- Jelle Demeestere, Anke Wouters, Soren Christensen, Robin Lemmens, Maarten G. LansbergStroke 2020 51 3
- Pedro Vilela, Howard A. RowleyEuropean Journal of Radiology 2017 96
- Marc-Antoine Labeyrie, Guillaume Turc, Agathe Hess, Patrice Hervo, Jean-Louis Mas, Jean-François Meder, Jean-Claude Baron, Emmanuel Touzé, Catherine OppenheimStroke 2012 43 11
- Adam S. Tunis, Matthew D. F. McInnes, Ramez Hanna, Kaisra EsmailRadiology 2013 269 2
- Adam S. Tunis, Matthew D. F. McInnes, Ramez Hanna, Kaisra EsmailRadiology 2013 269 2
- Visualizing Cell Death in Experimental Focal Cerebral Ischemia: Promises, Problems, and PerspectivesMarietta Zille, Tracy D Farr, Ingo Przesdzing, Jochen Müller, Clemens Sommer, Ulrich Dirnagl, Andreas WunderJournal of Cerebral Blood Flow & Metabolism 2012 32 2
- T. Chemmanam, B.C.V. Campbell, S. Christensen, Y. Nagakane, P.M. Desmond, C.F. Bladin, M.W. Parsons, C.R. Levi, P.A. Barber, G.A. Donnan, S.M. DavisNeurology 2010 75 12
- Manabu Inoue, Michael Mlynash, Soren Christensen, Hayley M. Wheeler, Matus Straka, Aaryani Tipirneni, Stephanie M. Kemp, Greg Zaharchuk, Jean-Marc Olivot, Roland Bammer, Maarten G. Lansberg, Gregory W. AlbersStroke 2014 45 4
- Fredrik N. Albach, Peter Brunecker, Tatiana Usnich, Kersten Villringer, Martin Ebinger, Jochen B. Fiebach, Christian H. NolteStroke 2013 44 4
- Albert J Yoo, Benjamin Pulli, R Gilberto GonzalezExpert Review of Cardiovascular Therapy 2011 9 7
- Christian B. van der Pol, Matthew D. F. McInnes, William Petrcich, Adam S. Tunis, Ramez Hanna, Terence J QuinnPLOS ONE 2015 10 3
- J. M. WardlawJournal of Internal Medicine 2010 267 2
- C. Rosso, A. Drier, D. Lacroix, G. Mutlu, C. Pires, S. Lehéricy, Y. Samson, D. DormontNeurology 2010 74 24
- Wiebke Kurre, Marta Aguilar-Pérez, Elisabeth Schmid, Wolfgang Sperber, Hansjörg Bäzner, Hans HenkesNeuroradiology 2014 56 5
- Hélène Raoult, François Eugène, Jean-Christophe Ferré, Jean-Christophe Gentric, Thomas Ronzière, Aymeric Stamm, Jean-Yves GauvritJournal of Neuroradiology 2013 40 4
- Jan SobeskyJournal of Cerebral Blood Flow & Metabolism 2012 32 7
- Davide Pacini, Luca Di Marco, Alessandro Leone, Caterina Tonon, Cinzia Pettinato, Cristina Fonti, David N. Manners, Roberto Di BartolomeoEuropean Journal of Cardio-Thoracic Surgery 2010 37 6
- Christian Federau, Michael Mlynash, Soren Christensen, Greg Zaharchuk, Brannon Cha, Maarten G. Lansberg, Max Wintermark, Gregory W. AlbersRadiology 2016 280 1
- Nirmalya Ghosh, Xiangpeng Yuan, Christine I Turenius, Beatriz Tone, Kamalakar Ambadipudi, Evan Y Snyder, Andre Obenaus, Stephen AshwalJournal of Cerebral Blood Flow & Metabolism 2012 32 12
- William R. Bireley, Johan L. K. Van Hove, Renata C. Gallagher, Laura Z. FentonPediatric Radiology 2012 42 4
- AMY S. TIDWELL, IAN D. ROBERTSONVeterinary Radiology & Ultrasound 2011 52 s1
- Chung-Ming Lo, Peng-Hsiang Hung, Daw-Tung LinJournal of Digital Imaging 2021 34 3
- Kohki Nakamura, Shigeto Naito, Takehito Sasaki, Kentaro Minami, Yutaka Take, Eri Goto, Satoru Shimizu, Yoshiaki Yamaguchi, Naoko Suzuki, Toshiaki Yano, Michiharu Senga, Koji Kumagai, Kenichi Kaseno, Nobusada Funabashi, Shigeru OshimaCirculation Journal 2016 80 4
- N. Asdaghi, B. C. V. Campbell, K. S. Butcher, J. I. Coulter, J. Modi, A. Qazi, M. Goyal, A. M. Demchuk, S. B. CouttsAmerican Journal of Neuroradiology 2014 35 4
- Tsuyoshi OHTA, Masanori MORIMOTO, Kenji OKADA, Maki FUKUDA, Hirokazu ONISHI, Noritaka MASAHIRA, Toshiki MATSUOKA, Takaya TSUNO, Mitsuhiro TAKEMURANeurologia medico-chirurgica 2018 58 4
- Yuan-Hsiung Tsai, Ming-Hsueh Lee, Hsu-Huei Weng, Sheng-Wei Chang, Jen-Tsung Yang, Yen-Chu Huang, Ching-Po LinPLoS ONE 2014 9 8
- Philip BarberSensors 2013 13 6
- R. Kabra, H. Robbie, S.E.J. ConnorClinical Radiology 2015 70 7
- Chelsea S. KidwellStroke 2013 44 2
- Susan A. Arnold, Simon R. Platt, Karine P. Gendron, Franklin D. WestFrontiers in Veterinary Science 2020 7
- Qing-Quan Zu, Sheng Liu, Xiao-Quan Xu, Shan-Shan Lu, Lei Sun, Hai-Bin ShiLaboratory Investigation 2013 93 7
- Bruce C. V. Campbell, I. Mhairi MacraeInternational Journal of Stroke 2015 10 2
- Andra L. Dingman, Nicholas V. Stence, Brent R. O'Neill, Stefan H. Sillau, Kevin E. ChapmanPediatric Neurology 2018 82
- Mohamad Abdalkader, James E. Siegler, Jin Soo Lee, Shadi Yaghi, Zhongming Qiu, Xiaochuan Huo, Zhongrong Miao, Bruce C.V. Campbell, Thanh N. NguyenJournal of Stroke 2023 25 1
- Graeme A Deuchar, David Brennan, Hugh Griffiths, I Mhairi Macrae, Celestine SantoshJournal of Cerebral Blood Flow & Metabolism 2013 33 9
- Seena Dehkharghani, Jalal AndreNeurosurgery 2017 80 5
- Christopher D d'Esterre, Richard I Aviv, Ting Yim LeeActa Radiologica 2012 53 4
- Ralph G.R. Thomas, G. Katherine Lymer, Paul A. Armitage, Francesca M. Chappell, Trevor Carpenter, Bartosz Karaszewski, Martin S. Dennis, Joanna M. WardlawJournal of Stroke and Cerebrovascular Diseases 2013 22 7
- Risto A. KauppinenProgress in Nuclear Magnetic Resonance Spectroscopy 2014 80
- Thanh N. Nguyen, Alicia C. Castonguay, James E. Siegler, Simon Nagel, Maarten G. Lansberg, Adam de Havenon, Sunil A. Sheth, Mohamad Abdalkader, Jenny P. Tsai, Gregory W. Albers, Hesham E. Masoud, Tudor G. Jovin, Sheila O. Martins, Raul G. Nogueira, Osama O. ZaidatStroke: Vascular and Interventional Neurology 2023 3 1
- Nicolas Carpentier, Myriam Edjlali, Fatna Bouhafs, Pauline Roca, David Calvet, Emmanuel Touzé, Jean-Louis Mas, Jean-François Méder, Catherine OppenheimJournal of Neuroradiology 2012 39 3
- Lakshini Gunasekera, Leonid Churilov, Peter Mitchell, Andrew Bivard, Gagan Sharma, Mark W. Parsons, Bernard YanNeuroradiology 2021 63 10
- Felix C. Ng, Bruce C. V. CampbellCurrent Neurology and Neuroscience Reports 2019 19 8
- Isabelle Ract, Jean-Christophe Ferré, Thomas Ronzière, Emmanuelle Leray, Béatrice Carsin-Nicol, Jean-Yves GauvritJournal of Neuroradiology 2014 41 1
- Zeguang Ren, Maxim Mokin, Clayton T. Bauer, Zhongrong Miao, W. Scott Burgin, Yongjun WangWorld Neurosurgery 2019 127
- Bryony L McGarry, Harriet J Rogers, Michael J Knight, Kimmo T Jokivarsi, Alejandra Sierra, Olli HJ Gröhn, Risto A KauppinenInternational Journal of Stroke 2016 11 6
- Johanna Ospel, Nathaniel Rex, Sandeep Kandregula, Mayank GoyalNeurotherapeutics 2023 20 3
- Ethem Murat ArsavaJournal of Neurochemistry 2012 123 s2
- Jiawei Pan, Jun Zhang, Weiyuan Huang, Xin Cheng, Yifeng Ling, Qiang Dong, Daoying GengJournal of Computer Assisted Tomography 2013 37 5
- Mark J R J Bouts, Ivo A C W Tiebosch, Annette van der Toorn, Jeroen Hendrikse, Rick M DijkhuizenJournal of Cerebral Blood Flow & Metabolism 2014 34 2
- Hanna Maria Dragoș, Adina Stan, Roxana Pintican, Diana Feier, Andrei Lebovici, Paul-Ștefan Panaitescu, Constantin Dina, Stefan Strilciuc, Dafin F. MuresanuDiagnostics 2023 13 5
- Zhenghua Liu, Xinlan XiaoNeuroradiology 2013 55 3
- Antonio Carlos Martins Maia, Bruno Vasconcelos Sobreira Guedes, Ademar Lucas, Antonio José da RochaNeuroimaging Clinics of North America 2011 21 1
- Anne Helmer, Tamar Wechsler, Yafit GilboaThe Journal of Alternative and Complementary Medicine 2021 27 6
- Zeguang Ren, Xiaochuan Huo, Jay Kumar, Ashutosh P. Jadhav, Vincent Costalat, Jens Fiehler, Martin Bendszus, Shinichi Yoshimura, Gaoting Ma, Xu Tong, Xuelei Zhang, Osama O. Zaidat, Tudor G. Jovin, David S. Liebeskind, Vitor Mendes Pereira, Zhongrong MiaoStroke: Vascular and Interventional Neurology 2022 2 5
- George M. Ghobrial, Nohra Chalouhi, Mahmoud Zohra, Richard T. Dalyai, Michelle L. Ghobrial, Fred Rincon, Adam E. Flanders, Stavropoula I. Tjoumakaris, Pascal Jabbour, Robert H. Rosenwasser, L. Fernando GonzalezJournal of Clinical Neuroscience 2014 21 12
- Reinoud P.H. Bokkers, Laurens J. De Cocker, M.J.P. van Osch, Nolan S. Hartkamp, J. HendrikseTopics in Magnetic Resonance Imaging 2016 25 2
- Xiang Zhou, Yashi Nan, Jieyang Ju, Jingyu Zhou, Huanhui Xiao, Silun WangCells 2022 11 16
- Robin A Damion, Michael J Knight, Bryony L McGarry, Rose Bosnell, Peter Jezzard, George WJ Harston, Davide Carone, James Kennedy, Salwa El-Tawil, Jennifer Elliot, Keith W Muir, Philip Clatworthy, Risto A KauppinenPhysics in Medicine & Biology 2019 64 9
- Islem Rekik, Stéphanie Allassonnière, Stanley Durrleman, Trevor Carpenter, Joanna WardlawComputational and Mathematical Methods in Medicine 2013 2013
- Shady Mourad Boss, Ramez Reda Moustafa, Magdy Ahmed Moustafa, Ahmed El Sadek, Mohamed Mahmoud Mostafa, Hany Mohamed ArefThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery 2019 55 1
- Samuel Emeriau, Azzedine Benaïssa, Olivier Toubas, Francis Pombourcq, Laurent PierotJournal of Neuroradiology 2016 43 2
- Varsha Muddasani, Adam de Havenon, J. Scott McNally, Hediyeh Baradaran, Matthew D. AlexanderTopics in Magnetic Resonance Imaging 2021 30 4
- Keizo Yasui, Noriyoshi Nakai, Amane Araki, Kazuya Kawabata, Shinichiro Yamada, Satoshi Yokoi, Ken Ohyama, Tomoo Mano, Norimasa Mitsuma, Yasuhiro Hasegawa, Tsutomu YanagiNosotchu 2013 35 5
- Li Chen, Ningning Zhao, Shan XuJournal of International Medical Research 2021 49 3
- Ourania Varsou, Michael S Stringer, Catarina Dinis Fernandes, Christian Schwarzbauer, Mary Joan MacLeodBMC Research Notes 2014 7 1
- Hai Zeng, Qingfeng ZhuFrontiers in Neurology 2024 15
- Vitus Gosch, Kersten Villringer, Ivana Galinovic, Ramanan Ganeshan, Sophie K. Piper, Jochen B. Fiebach, Ahmed KhalilFrontiers in Neurology 2023 14
- Enrico Fainardi, Giorgio Busto, Andrea MorottiEuropean Journal of Radiology Open 2023 11
- Wells I. Mangrum, Mustafa R. Bashir, Elmar M. Merkle, Allen W. Song, Michael J. Paldino2012
- Ximing Nie, Xiran Liu, Hao Yang, Feng Shi, Weibin Gu, Xinyi Hou, Yufei Wei, Qixuan Lu, Haiwei Bai, Jiaping Chen, Tianhang Liu, Hongyi Yan, Zhonghua Yang, Miao Wen, Yuesong Pan, Chao Huang, Long Wang, Liping LiuNeural Computing and Applications 2023 35 30
- Serge Weis, Michael Sonnberger, Andreas Dunzinger, Eva Voglmayr, Martin Aichholzer, Raimund Kleiser, Peter Strasser2019
- Julie G. Shulman, Mohamad AbdalkaderCONTINUUM: Lifelong Learning in Neurology 2023 29 1
- Individualized quantification of the benefit from reperfusion therapy using stroke predictive modelsBrice Ozenne, Tae‐Hee Cho, Irene Klærke Mikkelsen, Marc Hermier, Götz Thomalla, Salvador Pedraza, Pascal Roy, Yves Berthezène, Norbert Nighoghossian, Leif Østergaard, Jean‐Claude Baron, Delphine Maucort‐BoulchEuropean Journal of Neuroscience 2019 50 8
- Gaetano Barbagallo, Marcella Caggiula, Annalisa Rizzo, Vita Direnzo, Angela Lupo, Antonio Fasano, Cosimo Angelo Greco, Alfredo Pauciulo, Antonio Saponaro, Adriana Paladini, Leonardo BarbariniCurrent Medical Imaging Formerly Current Medical Imaging Reviews 2023 19 6
- Morin Beyeler, Fabienne Pohle, Loris Weber, Madlaine Mueller, Christoph C. Kurmann, Adnan Mujanovic, Leander Clénin, Eike Immo Piechowiak, Thomas Raphael Meinel, Philipp Bücke, Simon Jung, David Seiffge, Sara M. Pilgram-Pastor, Tomas Dobrocky, Marcel Arnold, Jan Gralla, Urs Fischer, Pasquale Mordasini, Johannes KaesmacherClinical Neuroradiology 2024 34 1
- Marco Colasurdo, Huanwen Chen, Dheeraj GandhiNeuroimaging Clinics of North America 2024 34 2
- Jakub Čivrný, Dorňák Tomáš, Marie ČernáNeuroradiology 2024 66 3
- Hiromi Ishikawa, Jiro Kitayama, Yoji Yoshikawa, Asako Nakamura, Hiroshi Nakane, Tetsuro Ago, Takanari KitazonoNosotchu 2014 36 4
- Quantifying blood-brain barrier permeability in patients with ischemic stroke using non-contrast MRINikolaos Mouchtouris, Isaiah Ailes, Reid Gooch, Christian Raimondo, Yazan Shamli Oghli, Stavropoula Tjoumakaris, Pascal Jabbour, Robert Rosenwasser, Mahdi AlizadehMagnetic Resonance Imaging 2024 109
- Byeong Joo Choi, Taedong Ok, Yunjung Choi, Kyung-Yul LeeJournal of Neurosonology and Neuroimaging 2022 14 1
- Ariel Iporre-Rivas, Dorothee Saur, Karl Rohr, Gerik Scheuermann, Christina GillmannJournal of Medical Imaging 2023 10 04
- Elizabeth Boudreau, Sharon C. Kerwin, Emily B. DuPont, Jonathan M. Levine, John F. GriffinFrontiers in Veterinary Science 2022 9
- Joji Inamasu, Yu Nakagawa, Masashi Nakatsukasa, Hidefumi Koh, Satoru MiyatakeNihon Kyukyu Igakukai Zasshi 2011 22 3
In this issue
Advertisement
Does Diffusion-Weighted Imaging Represent the Ischemic Core? An Evidence-Based Systematic Review
P.G. Kranz, J.D. Eastwood
American Journal of Neuroradiology Jun 2009, 30 (6) 1206-1212; DOI: 10.3174/ajnr.A1547
Jump to section
Related Articles
- No related articles found.
Cited By...
- Threshold-based Identification of Persistent Infarction after Successful Endovascular Treatment: Re-evaluating the "Core"
- Small cortical grey matter lesions show no persistent infarction in transient ischaemic attack? A prospective cohort study
- DWI Reversal Is Associated with Small Infarct Volume in Patients with TIA and Minor Stroke
- Early Diffusion-Weighted Imaging Reversal After Endovascular Reperfusion Is Typically Transient in Patients Imaged 3 to 6 Hours After Onset
- Complete Early Reversal of Diffusion-Weighted Imaging Hyperintensities After Ischemic Stroke Is Mainly Limited to Small Embolic Lesions
- MRI Biomarkers in Acute Ischemic Stroke: A Conceptual Framework and Historical Analysis
- Diffusion Lesion Reversal After Thrombolysis: A MR Correlate of Early Neurological Improvement
- Ischemic diffusion lesion reversal is uncommon and rarely alters perfusion-diffusion mismatch
- Diffusion-weighted MRI in acute stroke within the first 6 hours: 1.5 or 3.0 Tesla?
This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.
- The Infarct Core is Well Represented by the Acute Diffusion Lesion: Sustained Reversal is InfrequentBruce CV Campbell, Archana Purushotham, Soren Christensen, Patricia M Desmond, Yoshinari Nagakane, Mark W Parsons, Maarten G Lansberg, Michael Mlynash, Matus Straka, Deidre A De Silva, Jean-Marc Olivot, Roland Bammer, Gregory W Albers, Geoffrey A Donnan, Stephen M DavisJournal of Cerebral Blood Flow & Metabolism 2012 32 1
- Archana Purushotham, Bruce C. V. Campbell, Matus Straka, Michael Mlynash, Jean-Marc Olivot, Roland Bammer, Stephanie M. Kemp, Gregory W. Albers, Maarten G. LansbergInternational Journal of Stroke 2015 10 3
- Jelle Demeestere, Anke Wouters, Soren Christensen, Robin Lemmens, Maarten G. LansbergStroke 2020 51 3
- Pedro Vilela, Howard A. RowleyEuropean Journal of Radiology 2017 96
- Marc-Antoine Labeyrie, Guillaume Turc, Agathe Hess, Patrice Hervo, Jean-Louis Mas, Jean-François Meder, Jean-Claude Baron, Emmanuel Touzé, Catherine OppenheimStroke 2012 43 11
- Adam S. Tunis, Matthew D. F. McInnes, Ramez Hanna, Kaisra EsmailRadiology 2013 269 2
- Adam S. Tunis, Matthew D. F. McInnes, Ramez Hanna, Kaisra EsmailRadiology 2013 269 2
- Visualizing Cell Death in Experimental Focal Cerebral Ischemia: Promises, Problems, and PerspectivesMarietta Zille, Tracy D Farr, Ingo Przesdzing, Jochen Müller, Clemens Sommer, Ulrich Dirnagl, Andreas WunderJournal of Cerebral Blood Flow & Metabolism 2012 32 2
- T. Chemmanam, B.C.V. Campbell, S. Christensen, Y. Nagakane, P.M. Desmond, C.F. Bladin, M.W. Parsons, C.R. Levi, P.A. Barber, G.A. Donnan, S.M. DavisNeurology 2010 75 12
- Manabu Inoue, Michael Mlynash, Soren Christensen, Hayley M. Wheeler, Matus Straka, Aaryani Tipirneni, Stephanie M. Kemp, Greg Zaharchuk, Jean-Marc Olivot, Roland Bammer, Maarten G. Lansberg, Gregory W. AlbersStroke 2014 45 4
More in this TOC Section
Similar Articles
Advertisement