Brain Perfusion in Asphyxiated Newborns Treated with Therapeutic Hypothermia

P. Wintermark; A. Hansen; M.C. Gregas; J. Soul; M. Labrecque; R.L. Robertson; S.K. Warfield

doi:10.3174/ajnr.A2708

Research ArticlePediatrics

Open Access

Brain Perfusion in Asphyxiated Newborns Treated with Therapeutic Hypothermia

P. Wintermark, A. Hansen, M.C. Gregas, J. Soul, M. Labrecque, R.L. Robertson and S.K. Warfield

American Journal of Neuroradiology December 2011, 32 (11) 2023-2029; DOI: https://doi.org/10.3174/ajnr.A2708

P. Wintermark

aFrom the Division of Newborn Medicine (P.W., A.H., M.L.)

bDepartment of Radiology (P.W., R.L.R., S.K.W.)

eDivision of Newborn Medicine (P.W.), Montreal Children's McGill Hospital, Quebec, Ontario, Canada.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

A. Hansen

aFrom the Division of Newborn Medicine (P.W., A.H., M.L.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

M.C. Gregas

cClinical Research Program (M.C.G.)

dDepartment of Neurology (M.C.G., J.S.), Children's Hospital Boston, Boston, Massachusetts

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

J. Soul

dDepartment of Neurology (M.C.G., J.S.), Children's Hospital Boston, Boston, Massachusetts

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

M. Labrecque

aFrom the Division of Newborn Medicine (P.W., A.H., M.L.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

R.L. Robertson

bDepartment of Radiology (P.W., R.L.R., S.K.W.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

S.K. Warfield

bDepartment of Radiology (P.W., R.L.R., S.K.W.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Article
Figures & Data
Supplemental
Info & Metrics
Responses
References
PDF

Article Information

vol. 32 no. 11 2023-2029

DOI

https://doi.org/10.3174/ajnr.A2708

PubMed

21979494

Published By

American Journal of Neuroradiology

Print ISSN

0195-6108

Online ISSN

1936-959X

History

Received January 11, 2011
Accepted after revision April 17, 2011
Published online December 13, 2011.

Article Versions

Latest version (October 6, 2011 - 06:32).
Latest version (November 3, 2011 - 07:06).
You are viewing the most recent version of this article.

Author Information

P. Wintermarka,b,e,
A. Hansena,
M.C. Gregasc,d,
J. Sould,
M. Labrecquea,
R.L. Robertsonb and
S.K. Warfieldb

^aFrom the Division of Newborn Medicine (P.W., A.H., M.L.)
^bDepartment of Radiology (P.W., R.L.R., S.K.W.)
^cClinical Research Program (M.C.G.)
^dDepartment of Neurology (M.C.G., J.S.), Children's Hospital Boston, Boston, Massachusetts
^eDivision of Newborn Medicine (P.W.), Montreal Children's McGill Hospital, Quebec, Ontario, Canada.

Please address correspondence to Pia Wintermark, MD, Montreal Children's Hospital, Division of Newborn Medicine, 2300 Rue Tupper, C-920, Montréal QC H3H 1P3; e-mail: Pia.Wintermark{at}bluemail.ch

View Full Text

Altmetrics

Cited By...

99 Citations
Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

Cerebral Oxygen Metabolism in Neonatal Hypoxic Ischemic Encephalopathy during and after Therapeutic Hypothermia

Mathieu Dehaes, Alpna Aggarwal, Pei-Yi Lin, C Rosa Fortuno, Angela Fenoglio, Nadège Roche-Labarbe, Janet S Soul, Maria Angela Franceschini, P Ellen Grant

Journal of Cerebral Blood Flow & Metabolism 2014 34 1
Near-infrared spectroscopy versus magnetic resonance imaging to study brain perfusion in newborns with hypoxic–ischemic encephalopathy treated with hypothermia

P. Wintermark, A. Hansen, S.K. Warfield, D. Dukhovny, J.S. Soul

NeuroImage 2014 85
Arterial spin-labelling perfusion MRI and outcome in neonates with hypoxic-ischemic encephalopathy

Jill B. De Vis, Jeroen Hendrikse, Esben T. Petersen, Linda S. de Vries, Frank van Bel, Thomas Alderliesten, Simona Negro, Floris Groenendaal, Manon J. N. L. Benders

European Radiology 2015 25 1
Ultrafast Doppler Reveals the Mapping of Cerebral Vascular Resistivity in Neonates

Charlie Demené, Mathieu Pernot, Valérie Biran, Marianne Alison, Mathias Fink, Olivier Baud, Mickaël Tanter

Journal of Cerebral Blood Flow & Metabolism 2014 34 6
Outcomes of preterm infants treated with hypothermia for hypoxic-ischemic encephalopathy

Tamara I. Herrera, Laura Edwards, William F. Malcolm, P. Brian Smith, Kimberley A. Fisher, Carolyn Pizoli, Kathryn E. Gustafson, Ricki F. Goldstein, C. Michael Cotten, Ronald N. Goldberg, Margarita Bidegain

Early Human Development 2018 125
Brain Perfusion in Encephalopathic Newborns after Therapeutic Hypothermia

A. N. Massaro, M. Bouyssi-Kobar, T. Chang, L. G. Vezina, A. J. du Plessis, C. Limperopoulos

American Journal of Neuroradiology 2013 34 8
T1 and T2 values of human neonatal blood at 3 Tesla: Dependence on hematocrit, oxygenation, and temperature

Peiying Liu, Lina F. Chalak, Lisa C. Krishnamurthy, Imran Mir, Shin‐lei Peng, Hao Huang, Hanzhang Lu

Magnetic Resonance in Medicine 2016 75 4
Neuroimaging in the term newborn with neonatal encephalopathy

Jessica L. Wisnowski, Pia Wintermark, Sonia L. Bonifacio, Christopher D. Smyser, A. James Barkovich, A. David Edwards, Linda S. de Vries, Terrie E. Inder, Vann Chau

Seminars in Fetal and Neonatal Medicine 2021 26 5
Regional changes in brain perfusion during brain maturation measured non-invasively with Arterial Spin Labeling MRI in neonates

Jill B. De Vis, Esben T. Petersen, Linda S. de Vries, Floris Groenendaal, Karina J. Kersbergen, Thomas Alderliesten, Jeroen Hendrikse, Manon J.N.L. Benders

European Journal of Radiology 2013 82 3
Heterogeneous increases of regional cerebral blood flow during preterm brain development: Preliminary assessment with pseudo-continuous arterial spin labeled perfusion MRI

Minhui Ouyang, Peiying Liu, Tina Jeon, Lina Chalak, Roy Heyne, Nancy K. Rollins, Daniel J. Licht, John A. Detre, Timothy P.L. Roberts, Hanzhang Lu, Hao Huang

NeuroImage 2017 147
Preferential Cephalic Redistribution of Left Ventricular Cardiac Output during Therapeutic Hypothermia for Perinatal Hypoxic-Ischemic Encephalopathy

Ori Hochwald, Mohammad Jabr, Horacio Osiovich, Steven P. Miller, Patrick J. McNamara, Pascal M. Lavoie

The Journal of Pediatrics 2014 164 5
The ‘ouR‐HOPE’ approach for ethics and communication about neonatal neurological injury

Eric Racine, Emily Bell, Barbara Farlow, Steven Miller, Antoine Payot, Lisa Anne Rasmussen, Michael I Shevell, Donna Thomson, Pia Wintermark

Developmental Medicine & Child Neurology 2017 59 2
Evolution of pattern of injury and quantitative MRI on days 1 and 3 in term newborns with hypoxic–ischemic encephalopathy

Dawn Gano, Vann Chau, Kenneth J. Poskitt, Alan Hill, Elke Roland, Rollin Brant, Mark Chalmers, Steven P. Miller

Pediatric Research 2013 74 1
Impact of neonate haematocrit variability on the longitudinal relaxation time of blood: Implications for arterial spin labelling MRI

J.B. De Vis, J. Hendrikse, F. Groenendaal, L.S. de Vries, K.J. Kersbergen, M.J.N.L. Benders, E.T. Petersen

NeuroImage: Clinical 2014 4
Evaluation of perinatal arterial ischemic stroke using noninvasive arterial spin labeling perfusion MRI

Jill B. De Vis, Esben T. Petersen, Karina J. Kersbergen, Thomas Alderliesten, Linda S. de Vries, Frank van Bel, Floris Groenendaal, Petra M.A. Lemmers, Jeroen Hendrikse, Manon J.N.L. Benders

Pediatric Research 2013 74 3
Non-invasive MRI measurements of venous oxygenation, oxygen extraction fraction and oxygen consumption in neonates

J.B. De Vis, E.T. Petersen, T. Alderliesten, F. Groenendaal, L.S. de Vries, F. van Bel, M.J.N.L. Benders, J. Hendrikse

NeuroImage 2014 95
Arterial spin labeling in clinical pediatric imaging

M. Proisy, B. Bruneau, C. Rozel, C. Tréguier, K. Chouklati, L. Riffaud, P. Darnault, J.-C. Ferré

Diagnostic and Interventional Imaging 2016 97 2
Measurement of brain perfusion in newborns: Pulsed arterial spin labeling (PASL) versus pseudo-continuous arterial spin labeling (pCASL)

Elodie Boudes, Guillaume Gilbert, Ilana Ruth Leppert, Xianming Tan, G. Bruce Pike, Christine Saint-Martin, Pia Wintermark

NeuroImage: Clinical 2014 6
Magnetic Resonance Imaging in (Near-)Term Infants with Hypoxic-Ischemic Encephalopathy

Corline E. J. Parmentier, Linda S. de Vries, Floris Groenendaal

Diagnostics 2022 12 3
The challenges of neonatal magnetic resonance imaging

Owen J. Arthurs, Andrea Edwards, Topun Austin, Martin J. Graves, David J. Lomas

Pediatric Radiology 2012 42 10
Prematurity and brain perfusion: Arterial spin labeling MRI

Domenico Tortora, Peter Angelo Mattei, Riccardo Navarra, Valentina Panara, Rita Salomone, Andrea Rossi, John A. Detre, Massimo Caulo

NeuroImage: Clinical 2017 15
Automated Core–Penumbra Quantification in Neonatal Ischemic Brain Injury

Nirmalya Ghosh, Xiangpeng Yuan, Christine I Turenius, Beatriz Tone, Kamalakar Ambadipudi, Evan Y Snyder, Andre Obenaus, Stephen Ashwal

Journal of Cerebral Blood Flow & Metabolism 2012 32 12
Pathophysiology of Cerebral Hyperperfusion in Term Neonates With Hypoxic-Ischemic Encephalopathy: A Systematic Review for Future Research

Dianne G. Kleuskens, Filipe Gonçalves Costa, Kim V. Annink, Agnes van den Hoogen, Thomas Alderliesten, Floris Groenendaal, Manon J. N. Benders, Jeroen Dudink

Frontiers in Pediatrics 2021 9
Cerebral Lactate Concentration in Neonatal Hypoxic-Ischemic Encephalopathy: In Relation to Time, Characteristic of Injury, and Serum Lactate Concentration

Tai-Wei Wu, Benita Tamrazi, Kai-Hsiang Hsu, Eugenia Ho, Aaron J. Reitman, Matthew Borzage, Stefan Blüml, Jessica L. Wisnowski

Frontiers in Neurology 2018 9
Intraventricular hemorrhage in asphyxiated newborns treated with hypothermia: a look into incidence, timing and risk factors

Ghalia Al Yazidi, Elodie Boudes, Xianming Tan, Christine Saint-Martin, Michael Shevell, Pia Wintermark

BMC Pediatrics 2015 15 1
Acquisition Guidelines and Quality Assessment Tools for Analyzing Neonatal Diffusion Tensor MRI Data

A.M. Heemskerk, A. Leemans, A. Plaisier, K. Pieterman, M.H. Lequin, J. Dudink

American Journal of Neuroradiology 2013 34 8
Contrast-enhanced ultrasound of the pediatric brain

Misun Hwang, Carol E. Barnewolt, Jörg Jüngert, Francesco Prada, Anush Sridharan, Ryne A. Didier

Pediatric Radiology 2021 51 12
New Insights in Perinatal Arterial Ischemic Stroke by Assessing Brain Perfusion

Pia Wintermark, Simon K. Warfield

Translational Stroke Research 2012 3 2
Changes in brain perfusion in successive arterial spin labeling MRI scans in neonates with hypoxic-ischemic encephalopathy

Maïa Proisy, Isabelle Corouge, Antoine Legouhy, Amélie Nicolas, Valérie Charon, Nadia Mazille, Stéphanie Leroux, Bertrand Bruneau, Christian Barillot, Jean-Christophe Ferré

NeuroImage: Clinical 2019 24
Cerebral blood flow measurements in infants using look–locker arterial spin labeling

Marta Varela, Esben T. Petersen, Xavier Golay, Joseph V. Hajnal

Journal of Magnetic Resonance Imaging 2015 41 6
Management of comfort and sedation in neonates with neonatal encephalopathy treated with therapeutic hypothermia

Christopher McPherson, Adam Frymoyer, Cynthia M. Ortinau, Steven P. Miller, Floris Groenendaal

Seminars in Fetal and Neonatal Medicine 2021 26 4
Global and Regional Derangements of Cerebral Blood Flow and Diffusion Magnetic Resonance Imaging after Pediatric Cardiac Arrest

Leah C. Manchester, Vince Lee, Vincent Schmithorst, Patrick M. Kochanek, Ashok Panigrahy, Ericka L. Fink

The Journal of Pediatrics 2016 169
Transfontanellar duplex brain ultrasonography resistive indices as a prognostic tool in neonatal hypoxic-ischemic encephalopathy before and after treatment with therapeutic hypothermia

G J Gerner, V J Burton, A Poretti, T Bosemani, E Cristofalo, A Tekes, D Seyfert, C Parkinson, M Leppert, M Allen, T A G M Huisman, F J Northington, M V Johnston

Journal of Perinatology 2016 36 3
Assessment of cerebral blood flow in neonates and infants: A phase-contrast MRI study

Peiying Liu, Ying Qi, Zixuan Lin, Qiyong Guo, Xiaoming Wang, Hanzhang Lu

NeuroImage 2019 185
Measurement of pediatric regional cerebral blood flow from 6 months to 15 years of age in a clinical population

Aline Carsin-Vu, Isabelle Corouge, Olivier Commowick, Guillaume Bouzillé, Christian Barillot, Jean-Christophe Ferré, Maia Proisy

European Journal of Radiology 2018 101
Brain Perfusion Imaging in Neonates: An Overview

M. Proisy, S. Mitra, C. Uria-Avellana, M. Sokolska, N.J. Robertson, F. Le Jeune, J.-C. Ferré

American Journal of Neuroradiology 2016 37 10
Is therapeutic hypothermia during neonatal extracorporeal membrane oxygenation associated with intracranial hemorrhage?

Katherine Cashen, Ron W. Reeder, Christina Shanti, Heidi J. Dalton, J. Michael Dean, Kathleen L. Meert

Perfusion 2018 33 5
Cardiovascular management following hypoxic–ischemic encephalopathy in North America: need for physiologic consideration

Regan E. Giesinger, Philip T. Levy, J. Lauren Ruoss, Mohamed El Dib, Khorshid Mohammad, Pia Wintermark, Patrick J. McNamara

Pediatric Research 2021 90 3
Early Imaging and Adverse Neurodevelopmental Outcome in Asphyxiated Newborns Treated With Hypothermia

Fatema Al Amrani, Saskia Kwan, Guillaume Gilbert, Christine Saint-Martin, Michael Shevell, Pia Wintermark

Pediatric Neurology 2017 73
Increased Brain Perfusion Persists over the First Month of Life in Term Asphyxiated Newborns Treated with Hypothermia: Does it Reflect Activated Angiogenesis?

Henna Shaikh, Mirna Lechpammer, Frances E. Jensen, Simon K. Warfield, Anne H. Hansen, Bela Kosaras, Michael Shevell, Pia Wintermark

Translational Stroke Research 2015 6 3
Risk Factors for Intraventricular Hemorrhage in Term Asphyxiated Newborns Treated With Hypothermia

Ghalia Al Yazidi, Myriam Srour, Pia Wintermark

Pediatric Neurology 2014 50 6
In vivo Monitoring of Cerebral Hemodynamics in the Immature Rat: Effects of Hypoxia-Ischemia and Hypothermia

Erin M. Buckley, Shyama D. Patel, Benjamin F. Miller, Maria Angela Franceschini, Susan J. Vannucci

Developmental Neuroscience 2015 37 4-5
Cerebral blood flow and oxygenation in infants after birth asphyxia. Clinically useful information?

Gorm Greisen

Early Human Development 2014 90 10
Arterial spin labeling perfusion in neonates

Domenico Tortora, Mariasavina Severino, Andrea Rossi

Seminars in Fetal and Neonatal Medicine 2020 25 5
Injury and repair in perinatal brain injury: Insights from non-invasive MR perfusion imaging

Pia Wintermark

Seminars in Perinatology 2015 39 2
Changes in carotid blood flow after unilateral perinatal arterial ischemic stroke

Niek E. van der Aa, Eva D. Porsius, Jeroen Hendrikse, Britt J.M. van Kooij, Manon J.N.L. Benders, Linda S. de Vries, Floris Groenendaal

Pediatric Research 2012 72 1
Arterial Spin Labeling in Pediatric Neuroimaging

Srikala Narayanan, Vincent Schmithorst, Ashok Panigrahy

Seminars in Pediatric Neurology 2020 33
Continuous End-Tidal Carbon Dioxide Monitoring during Resuscitation of Asphyxiated Term Lambs

Praveen Kumar Chandrasekharan, Munmun Rawat, Jayasree Nair, Sylvia F. Gugino, Carmon Koenigsknecht, Daniel D. Swartz, Payam Vali, Bobby Mathew, Satyan Lakshminrusimha

Neonatology 2016 109 4
Does Early Cerebral Near-Infrared Spectroscopy Monitoring Predict Outcome in Neonates with Hypoxic Ischaemic Encephalopathy? A Systematic Review of Diagnostic Test Accuracy

Aisling A. Garvey, Andreea M. Pavel, Deirdre M. Murray, Geraldine B. Boylan, Eugene M. Dempsey

Neonatology 2022 119 1
Hybrid PET/MRI imaging in healthy unsedated newborn infants with quantitative rCBF measurements using 15O-water PET

Julie B Andersen, Ulrich Lindberg, Oline V Olesen, Didier Benoit, Claes N Ladefoged, Henrik BW Larsson, Liselotte Højgaard, Gorm Greisen, Ian Law

Journal of Cerebral Blood Flow & Metabolism 2019 39 5
Positron Emission Tomography/Magnetic Resonance Hybrid Scanner Imaging of Cerebral Blood Flow Using 15O-Water Positron Emission Tomography and Arterial Spin Labeling Magnetic Resonance Imaging in Newborn Piglets

Julie B Andersen, William S Henning, Ulrich Lindberg, Claes N Ladefoged, Liselotte Højgaard, Gorm Greisen, Ian Law

Journal of Cerebral Blood Flow & Metabolism 2015 35 11
Brain Temperature Is Increased During the First Days of Life in Asphyxiated Newborns: Developing Brain Injury Despite Hypothermia Treatment

Z.P. Owji, G. Gilbert, C. Saint-Martin, P. Wintermark

American Journal of Neuroradiology 2017 38 11
Cerebral Blood Flow of the Neonatal Brain after Hypoxic–Ischemic Injury

Luis Octavio Tierradentro-García, Sandra Saade-Lemus, Colbey Freeman, Matthew Kirschen, Hao Huang, Arastoo Vossough, Misun Hwang

American Journal of Perinatology 2023 40 05
Cerebral Perfusion Is Perturbed by Preterm Birth and Brain Injury

E.S. Mahdi, M. Bouyssi-Kobar, M.B. Jacobs, J. Murnick, T. Chang, C. Limperopoulos

American Journal of Neuroradiology 2018 39 7
Sex differences in cerebral blood flow following chorioamnionitis in healthy term infants

F R Koch, C L Wagner, D D Jenkins, M J Caplan, J K Perkel, L G Rollins, L D Katikaneni, D M Mulvihill

Journal of Perinatology 2014 34 3
Current Controversies in Newer Therapies to Treat Birth Asphyxia

Pia Wintermark

International Journal of Pediatrics 2011 2011
Cerebral blood flow velocity and oxygenation correlate predominantly with right ventricular function in cooled neonates with moderate-severe hypoxic-ischemic encephalopathy

Maria Jose Rodriguez, Araceli Corredera, Jose Martinez-Orgado, Luis Arruza

European Journal of Pediatrics 2020 179 10
Magnetic Resonance Imaging (MRI) and Prognostication in Neonatal Hypoxic-Ischemic Injury

Emily Bell, Lisa Anne Rasmussen, Barbara Mazer, Michael Shevell, Steven P. Miller, Anne Synnes, Jerome Y. Yager, Annette Majnemer, Nazeem Muhajarine, Isabelle Chouinard, Eric Racine

Journal of Child Neurology 2015 30 2
Evolution of Apparent Diffusion Coefficient and Fractional Anisotropy in the Cerebrum of Asphyxiated Newborns Treated with Hypothermia over the First Month of Life

Saskia Kwan, Elodie Boudes, Anouk Benseler, Guillaume Gilbert, Christine Saint-Martin, Michael Shevell, Pia Wintermark

Neural Plasticity 2015 2015
Medial Occipital Lobe Hyperperfusion Identified by Arterial Spin-Labeling: A Poor Prognostic Sign in Patients with Hypoxic-Ischemic Encephalopathy

A. de Havenon, A. Sultan-Qurraie, D. Tirschwell, W. Cohen, J. Majersik, J.B. Andre

American Journal of Neuroradiology 2015 36 12
Neonatal Neurology

Dearbhail Bracken-Roche, Michael Shevell, Eric Racine

2019 162
Evolution of early cerebral NIRS in hypoxic ischaemic encephalopathy

Aisling A. Garvey, John M. O'Toole, Vicki Livingstone, Brian Walsh, Michael Moore, Andreea M. Pavel, Lavinia Panaite, Mary Anne Ryan, Geraldine B. Boylan, Deirdre M. Murray, Eugene M. Dempsey

Acta Paediatrica 2022 111 10
Volpe's Neurology of the Newborn

Terrie E. Inder, Joseph J. Volpe

2018
Multidelay Arterial Spin Labeling MRI in the Assessment of Cerebral Blood Flow: Preliminary Clinical Experience in Pediatrics

Garima Suman, Jerome A. Rusin, R. Marc Lebel, Houchun H. Hu

Pediatric Neurology 2020 103
Role of Near-Infrared Spectroscopy in Monitoring the Clinical Course of Asphyxiated Neonates Treated with Hypothermia

Marwa Mohamed Farag, Ahmed Abd El-Halim Abd El-Raziq Khedr, MennattAllah Hassan Attia, Hesham Abd EL-Rahim Ghazal

American Journal of Perinatology 2024 41 04
Anoxic Brain Injury Detection with the Normalized Diffusion to ASL Perfusion Ratio: Implications for Blood-Brain Barrier Injury and Permeability

N. Li, M.A. Wingfield, J.P. Nickerson, D.R. Pettersson, J.M. Pollock

American Journal of Neuroradiology 2020 41 4
Brain contrast-enhanced ultrasonography and elastography in infants

Misun Hwang, Zeng Zhang, Joseph Katz, Colbey Freeman, Todd Kilbaugh

Ultrasonography 2022 41 4
Cerebral hemodynamics of hypoxic-ischemic encephalopathy neonates at different ages detected by arterial spin labeling imaging

Jianing Wang, Jia Li, Xiaoping Yin, Huan Zhou, Yating Zheng, Huaijun Liu

Clinical Hemorheology and Microcirculation 2022 81 4
Low b-value diffusion weighted imaging is promising in the diagnosis of brain death and hypoxic-ischemic injury secondary to cardiopulmonary arrest

Miriam E. Peckham, Jeffrey S. Anderson, Ulrich A. Rassner, Lubdha M. Shah, Peter J. Hinckley, Adam de Havenon, Seong-Eun Kim, J. Scott McNally

Critical Care 2018 22 1
MR imaging and outcome in neonatal HIBD models are correlated with sex: the value of diffusion tensor MR imaging and diffusion kurtosis MR imaging

Jieaoxue Bao, Xiaoan Zhang, Xin Zhao

Frontiers in Neuroscience 2023 17
Optimizing hemodynamic care in neonatal encephalopathy

Raymand Pang, Alison Mintoft, Rose Crowley, Mark Sellwood, Subhabrata Mitra, Nicola J. Robertson

Seminars in Fetal and Neonatal Medicine 2020 25 5
Cerebral perfusion changes of the basal ganglia and thalami in full-term neonates with hypoxic-ischaemic encephalopathy: a three-dimensional pseudo continuous arterial spin labelling perfusion magnetic resonance imaging study

Jibin Cao, Yongnan Mu, Xiaohan Xu, Huanhuan Li, Zequn Liu, Meiling Cao, Peng Wang, Wenge Sun, Lingling Cui

Pediatric Radiology 2022 52 8
Evaluating a Targeted Bedside Measure of Cerebral Perfusion in a Nonhuman Primate Model of Neonatal Hypoxic‐Ischemic Encephalopathy

Eric S. Peeples, Chikodinaka K. Ezeokeke, Sandra E. Juul, Pierre D. Mourad

Journal of Ultrasound in Medicine 2018 37 4
Diagnostic performance of arterial spin-labeled perfusion imaging and diffusion-weighted imaging in full-term neonatal hypoxic-ischemic encephalopathy

Linlin Meng, Qian Wang, Yifang Li, Xiangxing Ma, Wen Li, Qing Wang

Journal of Integrative Neuroscience 2021 20 4
Left Ventricular Function and Dimensions Are Altered Early in Infants Developing Brain Injury in the Setting of Neonatal Encephalopathy

Pierre Elias, Anie Lapointe, Pia Wintermark, Shiran Sara Moore, Daniela Villegas Martinez, Jessica Simoneau, Gabriel Altit

The Journal of Pediatrics 2023 261
Pearls and Pitfalls in Arterial Spin Labeling Perfusion-Weighted Imaging in Clinical Pediatric Imaging

David M. Kerner, Rahul Nikam, Vinay V.R. Kandula, Lauren W. Averill

Seminars in Ultrasound, CT and MRI 2022 43 1
Remote ischemic postconditioning increased cerebral blood flow and oxygenation assessed by magnetic resonance imaging in newborn piglets after hypoxia-ischemia

Sigrid Kerrn-Jespersen, Mads Andersen, Kristine Bennedsgaard, Ted Carl Kejlberg Andelius, Michael Pedersen, Kasper Jacobsen Kyng, Tine Brink Henriksen

Frontiers in Pediatrics 2022 10
Sedation and anesthesia for imaging of the infant and neonate—a brief review

Forrest P. Beaulieu, Gabriel Zuckerberg, Kristen Coletti, Emily Mapelli, John Flibotte, Spoorthi Sampath, Misun Hwang, Elizabeth T. Drum

Pediatric Radiology 2024 54 10
Arterial Spin-Labeling Perfusion for Neuroradiologists: The Essentials

T.J. Marini, D. Mistry, S. Jetty, H. Wang, E. Lin, J. Almast, N. Soni, S. Ellika

Neurographics 2022 12 3
Brain Contrast-Enhanced Ultrasound Evaluation of a Pediatric Swine Model

Misun Hwang, Kristina Khaw, Anush Sridharan, Laura Poznick, Thomas Hallowell, Nile Delso, Anna L. Roberts, Todd J. Kilbaugh

Ultrasound Quarterly 2022 38 1
Elevated cerebral perfusion in neonatal encephalopathy is associated with neurodevelopmental impairments

Ruth O’Gorman Tuura, Raimund Kottke, Barbara Brotschi, Carola Sabandal, Cornelia Hagmann, Beatrice Latal

Pediatric Research 2024
Long-term consequences of neonatal encephalopathy in the hypothermia era: protocol for a follow-up cohort study at 9 years of age

Marie Brossard-Racine, Emmanouille Rampakakis, Christine Lucas Tardif, Guillaume Gilbert, Angela White, Thuy Mai Luu, Anne Gallagher, Elana Pinchefsky, Tina Montreuil, Marie-Noelle Simard, Pia Wintermark

BMJ Open 2023 13 4
MRI brain imaging in neonates

Marcus Likeman

Paediatrics and Child Health 2014 24 9
Utility of Arterial Spin Labeling MRI in Pediatric Neuroimaging: A Pictorial Essay

Lauren W. Averill, Vinay V. R. Kandula

Current Radiology Reports 2017 5 8
Arterial Spin Labeling Magnetic Resonance Imaging

Jill B. De Vis, Esben T. Petersen, Jeroen Hendrikse

PET Clinics 2013 8 3
MRI predictors of long-term outcomes of neonatal hypoxic ischaemic encephalopathy: a primer for radiologists

Sheng-Che Hung, Yi-Fang Tu, Senyene E Hunter, Carolina Guimaraes

British Journal of Radiology 2024 97 1158
Mild hypothermia and hemorrhagic lesions in neonates with hypoxic-ischemic encephalopathy: experience in an outborn center

Immacolata Savarese, Martina Balestri, Fiammetta Piersigilli, Paola Giliberti, Francesca Campi, Jole Rechichi, Vito Mondì, Francesco Gesualdo, Daniela Longo, Maria Roberta Cilio, Andrea Dotta

The Journal of Maternal-Fetal & Neonatal Medicine 2015
A Systematic Review of the Relationship Between Neonatal Hypoxic-Ischemic Encephalopathy and Long-Term Cognitive Outcomes: Where Do We Stand?

Mohammed Y Abusaleem, Muawia Elsayed Elkhider Ebrahim, Nazim F Hamed, Mohamed Farahat Mohamed Eladwy

Cureus 2024
Bleeding Complications in Neonates Receiving Extracorporeal Membrane Oxygenation and Controlled Hypothermia

Swosti Joshi, Vilmaris Quinones Cardona, Erica Poletto, Ogechukwu Menkiti

American Journal of Perinatology 2024 41 08
Brain Injury in the Preterm and Term Neonate

Mai-Lan Ho, Alice C. Patton, David R. DeLone, Hosung Kim, Julie R. Gilbertson, Joel Felmlee, Robert E. Watson

Current Radiology Reports 2016 4 7
High‐Fidelity MRI Assessment of Cerebral Perfusion in Healthy Neonates Less Than 1 Week of Age

Zhiyi Hu, Dengrong Jiang, Jennifer Shepard, Yuto Uchida, Kenichi Oishi, Wen Shi, Peiying Liu, Doris Lin, Vivek Yedavalli, Aylin Tekes, William Christopher Golden, Hanzhang Lu

Journal of Magnetic Resonance Imaging 2025
Imaging in Neonates

Gregor Kasprian

2023
Impact of persistent pulmonary hypertension on cerebral oxygenation in infants with neonatal encephalopathy

Dimitrios Rallis, Hoda El-Shibiny, Eniko Szakmar, Aisling Garvey, Helen Christou, Mohamed El-Dib

Pediatric Research 2024
LncRNA TCONS_00067339 as a key regulatory factor inducing decreased cell viability and ferroptosis in neonatal hypoxic-ischemic brain damage

Yishi Li, Junfang Sun, Chunchi Lai, Ting Li, Lulu Zhang, Feng Zhang, Shiyi Ma, Mengya Sun, Hong Jiang

Brain Research 2025 1854
Manejo da sedação e anestesia em imagens pediátricas: particularidades e riscos em neonatos

Raphaela Nogueira Dutra, Elba Tania Ramos Oliveira, Jacqueline de Almeida Freitas, Ramon Magro Ferreira, Sérgio Mendes Dutra, Beatriz de Melo Lacerda Alves, Gabriel Franco Viana, Ieda Maira de Lima e Machado, Cristiane Barbosa Mendes

STUDIES IN HEALTH SCIENCES 2025 6 2
Pulse oximetry in pediatric care: Balancing advantages and limitations

Mohammed Al-Beltagi, Nermin Kamal Saeed, Adel Salah Bediwy, Reem Elbeltagi

World Journal of Clinical Pediatrics 2024 13 3
The Use of Cerebral Near-Infrared Spectroscopy in Neonatal Hypoxic-Ischemic Encephalopathy

Olivia Polise, Desi Newberry

Advances in Neonatal Care 2023 23 6
Ultrasound Diagnosis and Near-Infrared Spectroscopy in the Study of Encephalopathy in Neonates Born under Asphyxia: Narrative Review

Simeon N. Lavrentev, Anastasia S. Petrova, Olga F. Serova, Polina Vishnyakova, Maxim V. Kondratev, Anastasia S. Gryzunova, Nina I. Zakharova, Victor V. Zubkov, Denis N. Silachev

Children 2024 11 5
Utility of Point-of-care Ultrasound in Hypoxic-ischemic Brain Injury in Neonates

Akhil Maheshwari, Poonam Agrawal, Sujata Deshpande, Kirti Naranje, Anu Sharma, Pradeep Suryawanshi, Jayanta Hazarika, Gunjana Kumar, Alex Stevenson, Sreevidya Sreekantha

Newborn 2024 3 2

PreviousNext

In this issue

American Journal of Neuroradiology

Vol. 32, Issue 11

1 Dec 2011

Table of Contents
Index by author

Download PDF

Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Brain Perfusion in Asphyxiated Newborns Treated with Therapeutic Hypothermia

Message Subject (Your Name) has sent you a message from American Journal of Neuroradiology

Message Body (Your Name) thought you would like to see the American Journal of Neuroradiology web site.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Cite this article

P. Wintermark, A. Hansen, M.C. Gregas, J. Soul, M. Labrecque, R.L. Robertson, S.K. Warfield

Brain Perfusion in Asphyxiated Newborns Treated with Therapeutic Hypothermia

American Journal of Neuroradiology Dec 2011, 32 (11) 2023-2029; DOI: 10.3174/ajnr.A2708

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

0 Responses

Respond to this article

Bookmark this article

User Name *

Password *

Remember my user name & password.

Brain Perfusion in Asphyxiated Newborns Treated with Therapeutic Hypothermia

P. Wintermark, A. Hansen, M.C. Gregas, J. Soul, M. Labrecque, R.L. Robertson, S.K. Warfield

American Journal of Neuroradiology Dec 2011, 32 (11) 2023-2029; DOI: 10.3174/ajnr.A2708

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Purchase

Jump to section

Article
Figures & Data
Supplemental
Info & Metrics
Responses
References
PDF

PubMed
Google Scholar

Cited By...

Long-term consequences of neonatal encephalopathy in the hypothermia era: protocol for a follow-up cohort study at 9 years of age
Anoxic Brain Injury Detection with the Normalized Diffusion to ASL Perfusion Ratio: Implications for Blood-Brain Barrier Injury and Permeability
Cerebral Perfusion Is Perturbed by Preterm Birth and Brain Injury
Brain Temperature Is Increased During the First Days of Life in Asphyxiated Newborns: Developing Brain Injury Despite Hypothermia Treatment
Brain Perfusion Imaging in Neonates: An Overview
Medial Occipital Lobe Hyperperfusion Identified by Arterial Spin-Labeling: A Poor Prognostic Sign in Patients with Hypoxic-Ischemic Encephalopathy
Acquisition Guidelines and Quality Assessment Tools for Analyzing Neonatal Diffusion Tensor MRI Data
Brain Perfusion in Encephalopathic Newborns after Therapeutic Hypothermia

Crossref (99)
Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

Cerebral Oxygen Metabolism in Neonatal Hypoxic Ischemic Encephalopathy during and after Therapeutic Hypothermia

Mathieu Dehaes, Alpna Aggarwal, Pei-Yi Lin, C Rosa Fortuno, Angela Fenoglio, Nadège Roche-Labarbe, Janet S Soul, Maria Angela Franceschini, P Ellen Grant

Journal of Cerebral Blood Flow & Metabolism 2014 34 1
Near-infrared spectroscopy versus magnetic resonance imaging to study brain perfusion in newborns with hypoxic–ischemic encephalopathy treated with hypothermia

P. Wintermark, A. Hansen, S.K. Warfield, D. Dukhovny, J.S. Soul

NeuroImage 2014 85
Arterial spin-labelling perfusion MRI and outcome in neonates with hypoxic-ischemic encephalopathy

Jill B. De Vis, Jeroen Hendrikse, Esben T. Petersen, Linda S. de Vries, Frank van Bel, Thomas Alderliesten, Simona Negro, Floris Groenendaal, Manon J. N. L. Benders

European Radiology 2015 25 1
Ultrafast Doppler Reveals the Mapping of Cerebral Vascular Resistivity in Neonates

Charlie Demené, Mathieu Pernot, Valérie Biran, Marianne Alison, Mathias Fink, Olivier Baud, Mickaël Tanter

Journal of Cerebral Blood Flow & Metabolism 2014 34 6
Outcomes of preterm infants treated with hypothermia for hypoxic-ischemic encephalopathy

Tamara I. Herrera, Laura Edwards, William F. Malcolm, P. Brian Smith, Kimberley A. Fisher, Carolyn Pizoli, Kathryn E. Gustafson, Ricki F. Goldstein, C. Michael Cotten, Ronald N. Goldberg, Margarita Bidegain

Early Human Development 2018 125
Brain Perfusion in Encephalopathic Newborns after Therapeutic Hypothermia

A. N. Massaro, M. Bouyssi-Kobar, T. Chang, L. G. Vezina, A. J. du Plessis, C. Limperopoulos

American Journal of Neuroradiology 2013 34 8
T1 and T2 values of human neonatal blood at 3 Tesla: Dependence on hematocrit, oxygenation, and temperature

Peiying Liu, Lina F. Chalak, Lisa C. Krishnamurthy, Imran Mir, Shin‐lei Peng, Hao Huang, Hanzhang Lu

Magnetic Resonance in Medicine 2016 75 4
Neuroimaging in the term newborn with neonatal encephalopathy

Jessica L. Wisnowski, Pia Wintermark, Sonia L. Bonifacio, Christopher D. Smyser, A. James Barkovich, A. David Edwards, Linda S. de Vries, Terrie E. Inder, Vann Chau

Seminars in Fetal and Neonatal Medicine 2021 26 5
Regional changes in brain perfusion during brain maturation measured non-invasively with Arterial Spin Labeling MRI in neonates

Jill B. De Vis, Esben T. Petersen, Linda S. de Vries, Floris Groenendaal, Karina J. Kersbergen, Thomas Alderliesten, Jeroen Hendrikse, Manon J.N.L. Benders

European Journal of Radiology 2013 82 3
Heterogeneous increases of regional cerebral blood flow during preterm brain development: Preliminary assessment with pseudo-continuous arterial spin labeled perfusion MRI

Minhui Ouyang, Peiying Liu, Tina Jeon, Lina Chalak, Roy Heyne, Nancy K. Rollins, Daniel J. Licht, John A. Detre, Timothy P.L. Roberts, Hanzhang Lu, Hao Huang

NeuroImage 2017 147

Main menu

User menu

Search

American Journal of Neuroradiology

Brain Perfusion in Asphyxiated Newborns Treated with Therapeutic Hypothermia

Article Information

Article Versions

Author Information

Altmetrics

Cited By...

In this issue

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Indexed Content

Cases

Special Collections

More from AJNR

Multimedia

Resources

About Us

American Society of Neuroradiology