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Research ArticleBrain
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Anatomic Location and Somatotopic Arrangement of the Corticospinal Tract at the Cerebral Peduncle in the Human Brain

H.G. Kwon, J.H. Hong and S.H. Jang
American Journal of Neuroradiology December 2011, 32 (11) 2116-2119; DOI: https://doi.org/10.3174/ajnr.A2660
H.G. Kwon
aFrom the Department of Physical Therapy (H.G.K.), Graduate School of Rehabilitation Science, Daegu University, Daegu, Republic of Korea
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J.H. Hong
bDepartment of Physical Medicine and Rehabilitation (J.H.H., S.H.J.), College of Medicine, Yeungnam University, Taegu, Republic of Korea.
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S.H. Jang
bDepartment of Physical Medicine and Rehabilitation (J.H.H., S.H.J.), College of Medicine, Yeungnam University, Taegu, Republic of Korea.
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    Fig 1.

    A, Seed regions of interest were placed on the precentral knob (blue) for the hand and on the mediodorsal part (leg somatotopy) of the primary motor cortex for the leg (red). The target region of interest was placed on the known CST area of the pontomedullary junction. B, CSTs were constructed in both hemispheres (blue, hand; red, leg). The probability threshold is the point at which the corticopontocerebellar fiber disappears. C, Landmarks for measurement of the location of the CST (white line, midline of the interpeduncular fossa; white-lined rectangle, the boundary of the cerebral peduncle of the midbrain; a-a' double-headed arrow [red], mediolateral direction; b-b' double-headed arrow [green], anteroposterior direction). D, The location of the CST is shown at the upper and lower midbrain.

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  • Results of DTI parameters for the CST and average locations of the highest probability point of the CST at the CP of the midbraina

    RightLeftTotal
    HandLegHandLegHandLeg
    FA0.52 (±0.03)0.53 (±0.12)0.53 (±0.05)0.52 (±0.1)0.53 (±0.04)0.53 (±0.11)
    MD0.91 (±0.14)0.89 (±0.18)0.87 (±0.13)0.88 (±0.12)0.89 (±0.14)0.89 (±0.15)
    Tract volume693.56 (±419.98)494.86 (±298.43)618.3 (±372.14)567.7 (±284.4)655.93 (±396.25)531.28 (±292.09)
    Upper midbrain level
        Mediolateral59.41 (±9.6)70.77 (±7.84)61.39 (±9.8)69.20 (±7.78)60.46 (±9.69)69.98 (±7.8)
        Anteroposterior27.94 (±10.57)32.19 (±13.34)28.59 (±9.72)31.86 (±9.53)28.26 (±10.1)32.03 (±11.52)
    Lower midbrain level
        Mediolateral53.45 (±9.38)62.51 (±14.84)53.42 (±10.61)63 (±10.32)53.44 (±9.96)62.76 (±12.73)
        Anteroposterior28.23 (±8.37)31.51 (±10.28)32.15 (±11)35.68 (±10.85)30.19 (±9.91)33.59 (±10.72)
    • ↵a Values represent mean (±SD), MD × 10−3(mm2/s), and location (%).

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American Journal of Neuroradiology: 32 (11)
American Journal of Neuroradiology
Vol. 32, Issue 11
1 Dec 2011
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H.G. Kwon, J.H. Hong, S.H. Jang
Anatomic Location and Somatotopic Arrangement of the Corticospinal Tract at the Cerebral Peduncle in the Human Brain
American Journal of Neuroradiology Dec 2011, 32 (11) 2116-2119; DOI: 10.3174/ajnr.A2660

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Anatomic Location and Somatotopic Arrangement of the Corticospinal Tract at the Cerebral Peduncle in the Human Brain
H.G. Kwon, J.H. Hong, S.H. Jang
American Journal of Neuroradiology Dec 2011, 32 (11) 2116-2119; DOI: 10.3174/ajnr.A2660
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