Article Figures & Data
Figures
- Fig 1.
The Luna AES.
- Fig 2.
Representative case 5 in the Table. A, Pretreatment DSA demonstrates the aneurysm. B, DSA immediately after placement of Luna AES shows some cessation of intra-aneurysmal flow. C, DSA image at 5 minutes postimplantation shows total occlusion of the aneurysm. D and E, IVDSA at 1 month (D) and DSA at 3 months (E) show total occlusion. F, Gross examination at the neck orifice shows that the device is covered with a translucent membranous tissue. G, Photomicrograph of the aneurysm stained with Hematoxylin and Eosin (H&E; original magnification = 12.5×). This photomicrograph demonstrates that the aneurysmal cavity is filled with loose connective tissue and that a thick layer of neointima crosses the neck interface. H, Photomicrograph (enlargement of box in G) of the aneurysm's neck stained with H&E (original magnification = 40×). This image shows that the neointima consists of spindle cells, which appear to be smooth muscle cell-like.
- Fig 3.
Representative images from case 2 in the Table. A, DSA before treatment shows the aneurysm. B, Image at sacrifice shows a small remnant at the neck. C, Gross examination shows the device is partially covered with membranous tissue, such that the aneurysmal cavity is open to the parent artery through the holes of the device. D, Photomicrograph of the aneurysm stained with H&E (original magnification = 12.5×). The photomicrograph reveals thrombus at the neck, with no neointimal layer, and the remnant seen in B.
Tables
Summary of serial cases
No. Longest Width, Height of An. (mm) Neck, (mm) Size of Luna, (mm) Early Intra-Aneurysmal Flow Follow-Up (mo) Findings on Final Angiogram Gross Findings Microscopic Findings of Aneurysmal Dome Microscopic Findings of Neck 1 3.6 × 9.6 2.3 5.5 MD 1 NO Membranous tissue Loose connective tissue Thick neointima 2 3.5 × 11.8 3.0 7.5 CA 1 CO Small empty cavity Loose connective tissue No neointima 3 3.6 × 6.7 1.6 6 CA 1 CO Membranous tissue Loose connective tissue Thin neointima 4 4.3 × 7.6 2.0 6 CA 1 CO Membranous tissue Loose connective tissue with unorganized thrombus Thick neointima 5 3.1 × 8.5 2.5 6 CA 3 CO Membranous tissue Loose connective tissue Thick neointima 6 3.8 × 9.7 2.5 6 CA 3 CO Membranous tissue Loose connective tissue Thin neointima 7 3.2 × 8.4 2.4 6 CA 3 CO Membranous tissue Loose connective tissue Thin neointima 8 3.2 × 12.8 3.6 8 CA 3 CO Membranous tissue Loose connective tissue Thin neointima 9 3.5 × 9.5 3.2 6 CA 3 CO Membranous tissue Loose connective tissue Thick neointima 10 3.2 × 7.2 1.5 6 CA 3 CO Membranous tissue Loose connective tissue Thin neointima 11 4.3 × 12.3 2.5 6.5 MD 3 NO Membranous tissue Loose connective tissue Thin neointima 12 3.6 × 13 2.9 6.5 CA 3 CO Membranous tissue Loose connective tissue Thin neointima
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