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Research ArticleInterventional
Open Access

Influence of Hemodynamic Factors on Rupture of Intracranial Aneurysms: Patient-Specific 3D Mirror Aneurysms Model Computational Fluid Dynamics Simulation

G. Lu, L. Huang, X.L. Zhang, S.Z. Wang, Y. Hong, Z. Hu and D.Y. Geng
American Journal of Neuroradiology August 2011, 32 (7) 1255-1261; DOI: https://doi.org/10.3174/ajnr.A2461
G. Lu
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L. Huang
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X.L. Zhang
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S.Z. Wang
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Y. Hong
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Z. Hu
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D.Y. Geng
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  • Fig 1.
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    Fig 1.

    The aneurysm is divided from the parent artery by spheres.

  • Fig 2.
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    Fig 2.

    Distribution of WSS in 9 pairs of MANs at the systolic peak time (t =0.2 seconds). A, The ruptured group. B, The unruptured group. The numbering is annotated. The same color scale is selected for each pair of MANs.

  • Fig 3.
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    Fig 3.

    Distribution of OSI into 9 pairs of MANs. A, The ruptured group. B, The unruptured group. The numbering is annotated. The same color scale is selected for each pair of MANs.

Tables

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    Table 1:

    The common conditions of 9 patients with MANs

    Patient No.SexAge (yr)LocationRuptured Side
    1M55MCARight
    2F54C2Right
    3M61C2Right
    4F61C3Left
    5F52ACALeft
    6F44C3Right
    7F64C2Left
    8M42C3Right
    9M66C3Right
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    Table 2:

    The size of the included MANs

    Patient No.Ruptured Group (mm3)Unruptured Group (mm3)
    1392.941211.31
    258.2215.40
    3158.946.92
    492.384.16
    5106.544.92
    6112.3246.87
    7199.4452.63
    842.5932.39
    9121.56123.39
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    Table 3:

    WSS and OSI in MANs and their parent arteries

    Group/Patient No.Mean WSS of Aneurysms (Pa)Proportion of Low WSS Area to Whole Area of Aneurysms (%)Mean WSS of Parent Arteries (Pa)OSI of Aneurysms
    Ruptured
        14.5210.6611.510.1472
        27.802.7511.320.0188
        34.073.004.190.0797
        42.3738.193.440.0998
        57.282.7011.820.0150
        61.5448.494.710.0149
        79.842.3510.630.2062
        810.890.9111.360.1854
        910.060.759.810.0244
    Unruptured
        14.377.468.160.0485
        218.04015.910.0071
        35.332.844.230.0022
        42.3021.313.970.0542
        59.671.409.360.0053
        66.921.388.410.0132
        726.080.1013.660.0094
        88.421.1113.220.0137
        910.45011.320.0117
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American Journal of Neuroradiology: 32 (7)
American Journal of Neuroradiology
Vol. 32, Issue 7
1 Aug 2011
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Cite this article
G. Lu, L. Huang, X.L. Zhang, S.Z. Wang, Y. Hong, Z. Hu, D.Y. Geng
Influence of Hemodynamic Factors on Rupture of Intracranial Aneurysms: Patient-Specific 3D Mirror Aneurysms Model Computational Fluid Dynamics Simulation
American Journal of Neuroradiology Aug 2011, 32 (7) 1255-1261; DOI: 10.3174/ajnr.A2461

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Influence of Hemodynamic Factors on Rupture of Intracranial Aneurysms: Patient-Specific 3D Mirror Aneurysms Model Computational Fluid Dynamics Simulation
G. Lu, L. Huang, X.L. Zhang, S.Z. Wang, Y. Hong, Z. Hu, D.Y. Geng
American Journal of Neuroradiology Aug 2011, 32 (7) 1255-1261; DOI: 10.3174/ajnr.A2461
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  • Hemodynamic–morphological discriminant models for intracranial aneurysm rupture remain stable with increasing sample size
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