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Research ArticleSpine

The Role of MR Myelography with Intrathecal Gadolinium in Localization of Spinal CSF Leaks in Patients with Spontaneous Intracranial Hypotension

J.J. Akbar, P.H. Luetmer, K.M. Schwartz, C.H. Hunt, F.E. Diehn and L.J. Eckel
American Journal of Neuroradiology March 2012, 33 (3) 535-540; DOI: https://doi.org/10.3174/ajnr.A2815
J.J. Akbar
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P.H. Luetmer
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K.M. Schwartz
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C.H. Hunt
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F.E. Diehn
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L.J. Eckel
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    Fig 1.

    Patient with “classic” MR imaging findings of SIH on brain MR imaging. A, Brain sag on precontrast sagittal T1 imaging, with effacement of the suprasellar and prepontine cisterns, descent of the optic chiasm, draping of the floor of the third ventricle over the dorsum sella, descent of the midbrain, and extension of the tonsils through the foramen magnum. B, Diffuse pachymeningeal enhancement on postcontrast coronal T1 imaging.

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    Fig 2.

    A, Pre- and postintrathecal gadolinium fat-suppressed T1 images demonstrate typical artifacts, which may simulate a leak at C1-C2 seen in 6 of 41 of our patients. Note the inhomogeneous fat saturation on this precontrast sagittal T1 image at C1-2 (arrow). B, Recognizing this artifact on precontrast imaging is important because with the addition of intrathecal gadolinium, this inhomogeneous fat saturation can potentially mimic a leak (arrow).

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    Fig 3.

    Patient with CSF leaks at the left T3–4 and T4–5 interspaces, which are only visible on delayed GdM. A, Immediate left parasagittal fat-suppressed T1 imaging with normal findings. B−D, Three-hour delayed left parasagittal fat-suppressed T1 imaging demonstrates the CSF leaks (arrows), a finding which is also documented in the coronal plane (C and D) with evidence of contrast within the T3 and T4 foramina (arrows).

Tables

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  • Categorization and distribution of patients with CSF leak identified on GdM

    No. of PatientsCSF Leak on GdM (% of Patients in Group)
    Group 1: No CSF leak on CTM with at least 1 imaging study with positive findings
    Group 1a: Classic brain MR imaging with diffuse dural enhancement and brain sag14a2 (17%)
    Group 1b: Extradural fluid collection on MR spine imaging2a1 (50%)
    Group 2: No CSF leak on CTM with equivocal brain imaging (dural enhancement without brain sag or brain sag without dural enhancement) and negative findings on spine imaging31 (33%)
    Group 3: No CSF leak on CTM and negative findings on MR brain and spine imaging61 (14%)
    Group 4: Known CSF leak seen on CTM1712 (71%)
    Total number of patients in groups 1–44117 (41%)
    • ↵a One patient without a leak had both classic brain MR imaging and extradural fluid and is included in both groups 1a and 1b.

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American Journal of Neuroradiology: 33 (3)
American Journal of Neuroradiology
Vol. 33, Issue 3
1 Mar 2012
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Cite this article
J.J. Akbar, P.H. Luetmer, K.M. Schwartz, C.H. Hunt, F.E. Diehn, L.J. Eckel
The Role of MR Myelography with Intrathecal Gadolinium in Localization of Spinal CSF Leaks in Patients with Spontaneous Intracranial Hypotension
American Journal of Neuroradiology Mar 2012, 33 (3) 535-540; DOI: 10.3174/ajnr.A2815

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The Role of MR Myelography with Intrathecal Gadolinium in Localization of Spinal CSF Leaks in Patients with Spontaneous Intracranial Hypotension
J.J. Akbar, P.H. Luetmer, K.M. Schwartz, C.H. Hunt, F.E. Diehn, L.J. Eckel
American Journal of Neuroradiology Mar 2012, 33 (3) 535-540; DOI: 10.3174/ajnr.A2815
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