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Research ArticleBrain

Parenchymal Hypointense Foci Associated with Developmental Venous Anomalies: Evaluation by Phase-Sensitive MR Imaging at 3T

M. Takasugi, S. Fujii, Y. Shinohara, T. Kaminou, T. Watanabe and T. Ogawa
American Journal of Neuroradiology October 2013, 34 (10) 1940-1944; DOI: https://doi.org/10.3174/ajnr.A3495
M. Takasugi
aFrom the Division of Radiology (M.T., S.F., Y.S., T.K., T.O.), Department of Pathophysiological and Therapeutic Science
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S. Fujii
aFrom the Division of Radiology (M.T., S.F., Y.S., T.K., T.O.), Department of Pathophysiological and Therapeutic Science
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Y. Shinohara
aFrom the Division of Radiology (M.T., S.F., Y.S., T.K., T.O.), Department of Pathophysiological and Therapeutic Science
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T. Kaminou
aFrom the Division of Radiology (M.T., S.F., Y.S., T.K., T.O.), Department of Pathophysiological and Therapeutic Science
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T. Watanabe
bDivision of Neurosurgery (T.W.), Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Yonago, Tottori, Japan.
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T. Ogawa
aFrom the Division of Radiology (M.T., S.F., Y.S., T.K., T.O.), Department of Pathophysiological and Therapeutic Science
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  • Fig 1.
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    Fig 1.

    A 64-year-old man with DVA in the right frontal lobe. A, PSI shows DVA in the right frontal lobe (arrow) and hypointense foci around the DVA (arrowhead). B, T2-weighted image shows WMH around the DVA (arrow). C, DVA is enhanced by contrast agent administration, whereas hypointense foci are not enhanced on T1-weighted image.

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    Fig 2.

    A 25-year-old woman with DVA in the right cerebellum. A, PSI shows DVA in the right cerebellum and hypointense foci around the medullary veins (arrowhead). B, T2-weighted image shows WMH around the DVA (arrowhead).

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    Fig 3.

    A 75-year-old man with DVA in the right parieto-temporal lobe. A, PSI shows DVA in the right parieto-temporal lobe (arrow) and minute hypointense foci around the DVA (arrowhead). B, T2-weighted image shows WMH around the DVA (arrow).

Tables

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    Table 1:

    Location of cavernous malformation

    n
    Peripheral18
    Central11
    Both6
    • Note:—Total n = 35. Three patients were excluded because the hypointense foci were too large to assess.

    • View popup
    Table 2:

    Associations between hypointense foci and other factors

    Hypointense Foci (+) (n = 38)Hypointense Foci (−) (n = 23)
    n%n%
    WMHYes2668.4730.4
    No1231.61669.6
    LocationBasal ganglia/thalamus615.800
    Lobe1950.01565.2
    Cerebellum1026.3521.7
    Pons37.9313.0
    DepthPeriventricular1642.11356.5
    Juxtacortical821.1521.7
    Subcortical1436.8521.7
    Draining veinLong1539.51669.6
    Medium1436.8521.7
    Short923.728.7
    DirectionDeep1128.9417.4
    Superficial2771.11982.6
    • Note:—Total n = 61.

    • View popup
    Table 3:

    Patient symptoms and indications for examinations in the 2 groups based on hypointense foci

    Hypointense Foci (+) (n = 38)Hypointense Foci (−) (n = 21)n
    n%n%
    Symptoms or clinical indications for examinationsNo/follow-up of primary disease1152.41047.621
    Seizures583.3116.76
    Transient ischemic attack/stroke583.3116.76
    Dizziness, vertigo1253754
    Headache4100004
    Sensory disturbance266.7133.33
    Double vision2100002
    Dysarthria2100002
    Nerve palsy1501502
    SDH1501502
    Consciousness disturbance1100001
    ICH1100001
    Visual field disturbance1100001
    SAH0011001
    Syncope0011001
    Trauma0011001
    Unknown101
    • Note:—SDH indicates subdural hematoma.

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American Journal of Neuroradiology: 34 (10)
American Journal of Neuroradiology
Vol. 34, Issue 10
1 Oct 2013
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Cite this article
M. Takasugi, S. Fujii, Y. Shinohara, T. Kaminou, T. Watanabe, T. Ogawa
Parenchymal Hypointense Foci Associated with Developmental Venous Anomalies: Evaluation by Phase-Sensitive MR Imaging at 3T
American Journal of Neuroradiology Oct 2013, 34 (10) 1940-1944; DOI: 10.3174/ajnr.A3495

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Parenchymal Hypointense Foci Associated with Developmental Venous Anomalies: Evaluation by Phase-Sensitive MR Imaging at 3T
M. Takasugi, S. Fujii, Y. Shinohara, T. Kaminou, T. Watanabe, T. Ogawa
American Journal of Neuroradiology Oct 2013, 34 (10) 1940-1944; DOI: 10.3174/ajnr.A3495
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