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Research ArticleBrain

Structural Abnormalities in Patients with Insular/Peri-insular Epilepsy: Spectrum, Frequency, and Pharmacoresistance

M.-C. Chevrier, C. Bard, F. Guilbert and D.K. Nguyen
American Journal of Neuroradiology November 2013, 34 (11) 2152-2156; DOI: https://doi.org/10.3174/ajnr.A3636
M.-C. Chevrier
aFrom the Radiology Department (M.-C.C., C.B., F.G.)
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C. Bard
aFrom the Radiology Department (M.-C.C., C.B., F.G.)
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F. Guilbert
aFrom the Radiology Department (M.-C.C., C.B., F.G.)
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D.K. Nguyen
bNeurology Service (D.K.N.), Centre hospitalier de l'Université de Montréal (CHUM) – Hôpital Notre-Dame and Université de Montréal, Montreal, Quebec, Canada.
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REFERENCES

  1. 1.↵
    1. Chugani HT
    . Neuroimaging in Epilepsy. New York: Oxford University Press; 2011:3–37
  2. 2.↵
    1. Cakirer S,
    2. Başak M,
    3. Mutlu A,
    4. et al
    . MR imaging in epilepsy that is refractory to medical therapy. Eur Radiol 2002;12:549–58
    PubMed
  3. 3.↵
    1. Surbeck W,
    2. Bouthillier A,
    3. Nguyen DK
    . Refractory insular cortex epilepsy: clinical features, investigation and treatment. Future Neurol 2010;5:491–99
    CrossRef
  4. 4.↵
    1. Naidich TP,
    2. Kang E,
    3. Fatterpekar GM,
    4. et al
    . The insula: anatomic study and MR imaging display at 1.5T. AJNR Am J Neuroradiol 2004;25:222–32
    Abstract/FREE Full Text
  5. 5.↵
    1. Isnard J,
    2. Guenot M,
    3. Sindou M,
    4. et al
    . Clinical manifestations of insular lobe seizures: a stereo-electroencephalographic study. Epilepsia 2004;45:1079–90
    CrossRefPubMedWeb of Science
  6. 6.↵
    1. Ryvlin P,
    2. Minotti L,
    3. Demarquay G,
    4. et al
    . Nocturnal hypermotor seizures, suggesting frontal lobe epilepsy, can originate in the insula. Epilepsia 2006;47:755–65
    CrossRefPubMedWeb of Science
  7. 7.↵
    1. Nguyen DK,
    2. Nguyen DB,
    3. Malak R,
    4. et al
    . Revisiting the role of the insula in refractory partial epilepsy. Epilepsia 2009;50:510–20
    CrossRefPubMed
  8. 8.↵
    1. Lefkopoulos A,
    2. Haritanti A,
    3. Papadopoulou E,
    4. et al
    . Magnetic resonance imaging in 120 patients with intractable partial seizures: a preoperative assessment. Neuroradiology 2005;47:352–61
    CrossRefPubMed
  9. 9.↵
    1. Zentner J,
    2. Hufnagel A,
    3. Wolf HK,
    4. et al
    . Surgical treatment of temporal lobe epilepsy: clinical, radiological, and histopathological findings in 178 patients. J Neurol Neurosurg Psychiatry 1995;58:666–73
    Abstract/FREE Full Text
  10. 10.↵
    1. Duffau H,
    2. Capelle L,
    3. Lopes M,
    4. et al
    . Medically intractable epilepsy from insular low-grade gliomas: improvement after an extended lesionectomy. Acta Neurochir (Wien) 2002;144:563–72; discussion 572–73
    CrossRefPubMed
  11. 11.↵
    1. Lee JW,
    2. Wen PY,
    3. Hurwitz S,
    4. et al
    . Morphological characteristics of brain tumors causing seizures. Arch Neurol 2010;67:336–42
    CrossRefPubMedWeb of Science
  12. 12.↵
    1. Brodtkorb E,
    2. Nilsen G,
    3. Smevik O,
    4. et al
    . Epilepsy and anomalies of neuronal migration: MRI and clinical aspects. Acta Neurol Scand 1992;86:24–32
    PubMedWeb of Science
  13. 13.↵
    1. Kuzniecky RI
    . MRI in cerebral developmental malformations and epilepsy. Magn Reson Imaging 1995;13:1137–45
    CrossRefPubMedWeb of Science
  14. 14.↵
    1. Raymond AA,
    2. Fish DR,
    3. Sisodiya SM,
    4. et al
    . Abnormalities of gyration, heterotopias, tuberous sclerosis, focal cortical dysplasia, microdysgenesis, dysembryoplastic neuroepithelial tumour and dysgenesis of the archicortex in epilepsy. Clinical, EEG and neuroimaging features in 100 adult patients. Brain 1995;118:629–60
    Abstract/FREE Full Text
  15. 15.↵
    1. Leventer RJ,
    2. Jansen A,
    3. Pilz DT,
    4. et al
    . Clinical and imaging heterogeneity of polymicrogyria: a study of 328 patients. Brain 2010;133:1415–27
    Abstract/FREE Full Text
  16. 16.↵
    1. Vinters HV,
    2. Kerfoot C,
    3. Catania M,
    4. et al
    . Tuberous sclerosis-related gene expression in normal and dysplastic brain. Epilepsy Res 1998;32:12–23
    CrossRefPubMedWeb of Science
  17. 17.↵
    1. Stehbens WE
    . Etiology of intracranial berry aneurysms. J Neurosurg 1989;70:823–31
    PubMedWeb of Science
  18. 18.↵
    1. Malak R,
    2. Nguyen DK,
    3. Bojanowski MW
    . Non ruptured MCA aneurysms presenting with insular related symptoms. Can J Neurol Sci 2010;37:219–22
    PubMed
  19. 19.↵
    1. Cereda C,
    2. Ghika J,
    3. Maeder P,
    4. et al
    . Strokes restricted to the insular cortex. Neurology 2002;59:1950–55
    CrossRef
  20. 20.↵
    1. Bien CG,
    2. Widman G,
    3. Urbach H,
    4. et al
    . The natural history of Rasmussen's encephalitis. Brain 2002;125:1751–59
    Abstract/FREE Full Text
  21. 21.↵
    1. Granata T,
    2. Gobbi G,
    3. Spreafico R,
    4. et al
    . Rasmussen's encephalitis: early characteristics allow diagnosis. Neurology 2003;60:422–25
    CrossRef
  22. 22.↵
    1. Chiapparini L,
    2. Granata T,
    3. Farina I,
    4. et al
    . Diagnostic imaging in 13 cases of Rasmussen's encephalitis: can early MRI suggest the diagnosis? Neuroradiology 2003;45:171–83
    PubMedWeb of Science
  23. 23.↵
    1. Wagner J,
    2. Schoene-Bake JC,
    3. Bien CG,
    4. et al
    . Automated 3D MRI volumetry reveals regional atrophy differences in Rasmussen encephalitis. Epilepsia 2012;53:613–21
    CrossRefPubMed
  24. 24.↵
    1. Taillandier L,
    2. Duffau H
    . Epilepsy and insular grade II gliomas: an interdisciplinary point of view from a retrospective monocentric series of 46 cases. Neurosurg Focus 2009;27:E8
    PubMed
  25. 25.↵
    1. Caveness WF
    . Epilepsy, a product of trauma in our time. Epilepsia 1976;17:207–15
    CrossRefPubMedWeb of Science
  26. 26.↵
    1. Annegers JF,
    2. Hauser WA,
    3. Coan SP,
    4. et al
    . A population-based study of seizures after traumatic brain injuries. N Engl J Med 1998;338:20–24
    CrossRefPubMedWeb of Science
  27. 27.↵
    1. Pomeroy SL,
    2. Holmes SJ,
    3. Dodge PR,
    4. et al
    . Seizures and other neurologic sequelae of bacterial meningitis in children. N Engl J Med 1990;323:1651–57
    CrossRefPubMedWeb of Science
  28. 28.↵
    1. Gupta S,
    2. Naheedy M,
    3. Elias D,
    4. et al
    . Post infarction seizures: a clinical study. Stroke 1988;19:1477–81
    Abstract/FREE Full Text
  29. 29.↵
    1. Aghakhani Y,
    2. Rosati A,
    3. Dubeau F,
    4. et al
    . Patients with temporoparietal ictal symptoms and inferomesial EEG do not benefit from anterior temporal resection. Epilepsia 2004;45:230–36
    CrossRefPubMedWeb of Science
  30. 30.↵
    1. Harroud A,
    2. Bouthillier A,
    3. Weil A,
    4. et al
    . Temporal lobe epilepsy surgery failures: a review. Epilepsy Res Treat 2012;201651
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American Journal of Neuroradiology: 34 (11)
American Journal of Neuroradiology
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M.-C. Chevrier, C. Bard, F. Guilbert, D.K. Nguyen
Structural Abnormalities in Patients with Insular/Peri-insular Epilepsy: Spectrum, Frequency, and Pharmacoresistance
American Journal of Neuroradiology Nov 2013, 34 (11) 2152-2156; DOI: 10.3174/ajnr.A3636

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Structural Abnormalities in Patients with Insular/Peri-insular Epilepsy: Spectrum, Frequency, and Pharmacoresistance
M.-C. Chevrier, C. Bard, F. Guilbert, D.K. Nguyen
American Journal of Neuroradiology Nov 2013, 34 (11) 2152-2156; DOI: 10.3174/ajnr.A3636
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  • The role of magnetoencephalography in the presurgical evaluation of patients with MRI-negative operculo-insular epilepsy
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  • The Value of Regional Cerebral Blood Flow SPECT and FDG PET in Operculoinsular Epilepsy
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  • Proton MR Spectroscopy in Patients with Nonlesional Insular Cortex Epilepsy Confirmed by Invasive EEG Recordings
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    Journal of Neuroimaging 2017 27 5
  • Invasive Insular Sampling in Pediatric Epilepsy: A Single-Institution Experience
    Luke D Tomycz, Andrew T Hale, Ali S Haider, Dave F Clarke, Mark R Lee
    Operative Neurosurgery 2018 15 3
  • Evaluation of olfactory and gustatory changes in patients with mesial temporal lobe epilepsy
    Bengi G. Türk, Barış Metin, Hakan Tekeli, Özden Aksu Sayman, Osman Kızılkılıç, Mustafa Uzan, Çiğdem Özkara
    Seizure 2020 75
  • Stereo-EEG exploration in the insula/operculum in paediatric patients with refractory epilepsy
    Pablo Kappen, Christin Eltze, Martin Tisdall, J. Helen Cross, Rachel Thornton, Friederike Moeller
    Seizure 2020 78

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