Prospective Comparison of Angio-Seal versus Manual Compression for Hemostasis after Neurointerventional Procedures under Systemic Heparinization

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Fig 1.
Comparison of hemostasis times for the number of patients receiving Angio-Seal versus manual compression, including a comparison of puncture techniques.
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Fig 2.
Right common iliac artery angiogram showing occlusion at the common femoral artery (A) and revascularization after angioplasty (B).

Table 1:

Complication rates and a comparison of hematoma rates between Angio-Seal and manual compression at different ACT levels^{^a}

↵a Complication rate (hematoma >10 cm) 0.96 (1.11)% for Angio-Seal and 4.28 (2.98)% for manual compression. Patient numbers and complication rates in parentheses.
↵b Four patients with bilateral arteriotomies closed by Angio-Seal and manual compression, respectively.
↵c One patient with bilateral Angio-Seal and bilateral hematomas simultaneously.

Table 2:

Results of uni- and multivariate logistic regression analysis derived from hematoma development and independent predictors

Variable	Univariate			Multivariate
Variable	OR	95% CI^{^a}	P Value	OR	95% CI^{^a}	P Value
ACT time (sec)
250–300	1 (baseline)			1 (baseline)
300–350	3.3	1.2–8.8	.019^{^b}	4.5	1.5–13.2	.006^{^b}
350–500	3.4	1.1–11.2	.041^{^b}	5.0	1.4–18.0	.015^{^b}
Angio-Seal use	0.3	0.1–0.7	.003^{^b}	0.2	0.1–0.5	.001^{^b}
Age	1.0	1.00–1.02	.928
Sex	1.4	0.6–3.2	.426
Side	0.99	0.3–3.1	.984
Puncture technique (single- vs double-wall)	1.2	0.6–2.3	.658