Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • ASNR Foundation Special Collection
    • Most Impactful AJNR Articles
    • Photon-Counting CT
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • ASNR Foundation Special Collection
    • Most Impactful AJNR Articles
    • Photon-Counting CT
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR is seeking candidates for the AJNR Podcast Editor. Read the position description.

Research ArticleBrain

The Impact of Arterial Collateralization on Outcome after Intra-Arterial Therapy for Acute Ischemic Stroke

S. Seeta Ramaiah, L. Churilov, P. Mitchell, R. Dowling and B. Yan
American Journal of Neuroradiology April 2014, 35 (4) 667-672; DOI: https://doi.org/10.3174/ajnr.A3862
S. Seeta Ramaiah
aFrom the Melbourne Brain Centre (S.S.R., B.Y.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
L. Churilov
cDepartment of Mathematics and Statistics (L.C.)
dNational Stroke Research Institute (L.C.), Florey Neuroscience Institutes, Austin Health, University of Melbourne, Parkville, Victoria, Australia.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
P. Mitchell
bNeurointervention Service (P.M., R.D., B.Y.), Department of Radiology, Royal Melbourne Hospital, Parkville, Victoria, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
R. Dowling
bNeurointervention Service (P.M., R.D., B.Y.), Department of Radiology, Royal Melbourne Hospital, Parkville, Victoria, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
B. Yan
aFrom the Melbourne Brain Centre (S.S.R., B.Y.)
bNeurointervention Service (P.M., R.D., B.Y.), Department of Radiology, Royal Melbourne Hospital, Parkville, Victoria, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995;333:1581–87
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Wahlgren N,
    2. Ahmed N,
    3. Eriksson N,
    4. et al
    . Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST). Stroke 2008;39:3316–22
    Abstract/FREE Full Text
  3. 3.↵
    1. Lees KR,
    2. Bluhmki E,
    3. von Kummer R,
    4. et al
    . Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet 2010;375:1695–703
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Bhatia R,
    2. Hill MD,
    3. Shobha N,
    4. et al
    . Low rates of acute recanalization with intravenous recombinant tissue plasminogen activator in ischemic stroke: real-world experience and a call for action. Stroke 2010;41:2254–58
    Abstract/FREE Full Text
  5. 5.↵
    1. Christou I,
    2. Felberg RA,
    3. Demchuk AM,
    4. et al
    . Intravenous tissue plasminogen activator and flow improvement in acute ischemic stroke patients with internal carotid artery occlusion. J Neuroimaging 2002;12:119–23
    CrossRefPubMedWeb of Science
  6. 6.↵
    1. Zangerle A,
    2. Kiechl S,
    3. Spiegel M,
    4. et al
    . Recanalization after thrombolysis in stroke patients: predictors and prognostic implications. Neurology 2007;68:39–44
    CrossRef
  7. 7.↵
    1. Meyers PM,
    2. Schumacher HC,
    3. Connolly ES Jr.,
    4. et al
    . Current status of endovascular stroke treatment. Circulation 2011;123:2591–601
    FREE Full Text
  8. 8.↵
    1. Smith WS,
    2. Sung G,
    3. Saver J,
    4. et al
    . Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial. Stroke 2008;39:1205–12
    Abstract/FREE Full Text
  9. 9.↵
    1. Clark W,
    2. Lutsep H,
    3. Barnwell S,
    4. et al
    . The Penumbra Pivotal Stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease. Stroke 2009;40:2761–68
    Abstract/FREE Full Text
  10. 10.↵
    1. Broderick JP,
    2. Palesch YY,
    3. Demchuk AM,
    4. et al.
    , for the Interventional Management of Stroke (IMS) III Investigators. Endovascular therapy after intravenous t-PA versus t-PA alone for stroke. N Engl J Med 2013;368:893–903
    CrossRefPubMedWeb of Science
  11. 11.↵
    1. Ciccone A,
    2. Valvassori L,
    3. Nichelatti M,
    4. et al
    . Endovascular treatment for acute ischemic stroke. N Engl J Med 2013;368:904–13
    CrossRefPubMedWeb of Science
  12. 12.↵
    1. Chimowitz MI
    . Endovascular treatment for acute ischemic stroke: still unproven. N Engl J Med 2013;368:954–55
  13. 13.↵
    1. Dalkara T,
    2. Arsava EM
    . Can restoring incomplete microcirculatory reperfusion improve stroke outcome after thrombolysis? J Cereb Blood Flow Metab 2012;32:2091–209
    CrossRefPubMed
  14. 14.↵
    1. Miteff F,
    2. Levi CR,
    3. Bateman GA,
    4. et al
    . The independent predictive utility of computed tomography angiographic collateral status in acute ischaemic stroke. Brain 2009;132(pt 8):2231–2238
    Abstract/FREE Full Text
  15. 15.↵
    1. Bang OY,
    2. Saver JL,
    3. Buck BH,
    4. et al.
    , for the UCLA Collateral Investigators. Impact of collateral flow on tissue fate in acute ischaemic stroke. J Neurol Neurosurg Psychiatry 2007;79:625–29
    CrossRefPubMed
  16. 16.↵
    1. Bang OY,
    2. Saver JL,
    3. Kim SJ,
    4. et al
    . Collateral flow predicts response to endovascular therapy for acute ischemic stroke. Stroke 2011;42:693–99
    Abstract/FREE Full Text
  17. 17.↵
    1. Tan JC,
    2. Dillon WP,
    3. Liu S,
    4. et al
    . Systematic comparison of perfusion-CT and CT-angiography in acute stroke patients. Ann Neurol 2007;61:533–43
    CrossRefPubMedWeb of Science
  18. 18.↵
    1. Rosenthal ES,
    2. Schwamm LH,
    3. Roccatagliata L,
    4. et al
    . Role of recanalization in acute stroke outcome: rationale for a CT angiogram-based “benefit of recanalization” model. AJNR Am J Neuroradiol 2008;29:1471–75
    Abstract/FREE Full Text
  19. 19.↵
    1. Maas MB,
    2. Lev MH,
    3. Ay H,
    4. et al
    . Collateral vessels on CT angiography predict outcome in acute ischemic stroke. Stroke 2009;40:3001–05
    Abstract/FREE Full Text
  20. 20.↵
    1. Lima FO,
    2. Furie KL,
    3. Silva GS,
    4. et al
    . The pattern of leptomeningeal collaterals on CT angiography is a strong predictor of long-term functional outcome in stroke patients with large vessel intracranial occlusion. Stroke 2010;41:2316–22
    Abstract/FREE Full Text
  21. 21.↵
    1. Menon BK,
    2. Smith EE,
    3. Modi J,
    4. et al
    . Regional leptomeningeal score on CT angiography predicts clinical and imaging outcomes in patients with acute anterior circulation occlusions. AJNR Am J Neuroradiol 2011;32:1640–45
    Abstract/FREE Full Text
  22. 22.↵
    1. Higashida RT,
    2. Anthony J Furlan,
    3. et al
    . Trial design and reporting standards for intraarterial cerebral thrombolysis for acute ischemic stroke. J Vasc Interv Radiol 2003;14(9 Pt 2):S493–94
    CrossRefPubMed
  23. 23.↵
    1. Souza LC,
    2. Yoo AJ,
    3. Chaudhry ZA,
    4. et al
    . Malignant CTA collateral profile is highly specific for large admission DWI infarct core and poor outcome in acute stroke. AJNR Am J Neuroradiol 2012;33:1331–36
    Abstract/FREE Full Text
  24. 24.↵
    1. Angermaier A,
    2. Langner S,
    3. Kirsch M,
    4. et al
    . CT-angiographic collateralization predicts final infarct volume after intra-arterial thrombolysis for acute anterior circulation ischemic stroke. Cerebrovasc Dis 2011;31:177–84
    CrossRefPubMed
  25. 25.↵
    1. Tan IY,
    2. Demchuk AM,
    3. Hopyan J,
    4. et al
    . CT angiography clot burden score and collateral score: correlation with clinical and radiologic outcomes in acute middle cerebral artery infarct. AJNR Am J Neuroradiol 2009;30:525–31
    Abstract/FREE Full Text
  26. 26.↵
    1. Liebeskind DS
    . Collaterals in acute stroke: beyond the clot. Neuroimaging Clin N Am 2005;15:553–573, x
    CrossRefPubMedWeb of Science
  27. 27.↵
    1. Wildermuth S,
    2. Knauth M,
    3. Brandt T,
    4. et al
    . Role of CT angiography in patient selection for thrombolytic therapy in acute hemispheric stroke. Stroke 1998;29:935–38
    Abstract/FREE Full Text
  28. 28.↵
    1. Liebeskind DS
    . Collateral circulation. Stroke 2003;34:2279–84
    Abstract/FREE Full Text
  29. 29.↵
    1. Tomsick TA,
    2. Khatri P,
    3. Jovin T,
    4. et al
    . Equipoise among recanalization strategies. Neurology 2010;74:1069–76
    CrossRef
  30. 30.↵
    1. Hallevi Hen,
    2. Barreto AD,
    3. Liebeskind DS,
    4. et al
    . Identifying patients at high risk for poor outcome after intra-arterial therapy for acute ischemic stroke. Stroke 2009;40:1780–85
    Abstract/FREE Full Text
  31. 31.↵
    1. Flint AC,
    2. Kamel H,
    3. Rao VA,
    4. et al
    . Validation of the Totaled Heath Risks In Vascular Events (THRIVE) score for outcome prediction in endovascular stroke treatment. Int J Stroke 2014;9:32–39
    CrossRefPubMed
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 35 (4)
American Journal of Neuroradiology
Vol. 35, Issue 4
1 Apr 2014
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
The Impact of Arterial Collateralization on Outcome after Intra-Arterial Therapy for Acute Ischemic Stroke
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
S. Seeta Ramaiah, L. Churilov, P. Mitchell, R. Dowling, B. Yan
The Impact of Arterial Collateralization on Outcome after Intra-Arterial Therapy for Acute Ischemic Stroke
American Journal of Neuroradiology Apr 2014, 35 (4) 667-672; DOI: 10.3174/ajnr.A3862

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
The Impact of Arterial Collateralization on Outcome after Intra-Arterial Therapy for Acute Ischemic Stroke
S. Seeta Ramaiah, L. Churilov, P. Mitchell, R. Dowling, B. Yan
American Journal of Neuroradiology Apr 2014, 35 (4) 667-672; DOI: 10.3174/ajnr.A3862
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Circle of Willis variation and outcome after intra-arterial treatment
  • Impact of single phase CT angiography collateral status on functional outcome over time: results from the MR CLEAN Registry
  • Interrogating the Functional Correlates of Collateralization in Patients with Intracranial Stenosis Using Multimodal Hemodynamic Imaging
  • Impact of collaterals on the efficacy and safety of endovascular treatment in acute ischaemic stroke: a systematic review and meta-analysis
  • Collateral flow as causative of good outcomes in endovascular stroke therapy
  • Crossref (23)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Impact of collaterals on the efficacy and safety of endovascular treatment in acute ischaemic stroke: a systematic review and meta-analysis
    Xinyi Leng, Hui Fang, Thomas W H Leung, Chen Mao, Zhongrong Miao, Liping Liu, Ka Sing Wong, David S Liebeskind
    Journal of Neurology, Neurosurgery & Psychiatry 2016 87 5
  • The cerebral collateral circulation: Relevance to pathophysiology and treatment of stroke
    Myron D. Ginsberg
    Neuropharmacology 2018 134
  • Collateral flow as causative of good outcomes in endovascular stroke therapy
    Sunil A Sheth, Nerses Sanossian, Qing Hao, Sidney Starkman, Latisha K Ali, Doojin Kim, Nestor R Gonzalez, Satoshi Tateshima, Reza Jahan, Gary R Duckwiler, Jeffrey L Saver, Fernando Vinuela, David S Liebeskind
    Journal of NeuroInterventional Surgery 2016 8 1
  • Expanding the concept of neuroprotection for acute ischemic stroke: The pivotal roles of reperfusion and the collateral circulation
    Myron D. Ginsberg
    Progress in Neurobiology 2016 145-146
  • Determinants of leptomeningeal collateral flow in stroke patients with a middle cerebral artery occlusion
    Tom van Seeters, Geert Jan Biessels, L. Jaap Kappelle, Yolanda van der Graaf, Birgitta K. Velthuis
    Neuroradiology 2016 58 10
  • Impact of single phase CT angiography collateral status on functional outcome over time: results from the MR CLEAN Registry
    Ivo GH Jansen, Maxim JHL Mulder, Robert-Jan B Goldhoorn, Anna MM Boers, Adriaan CGM van Es, Lonneke SF Yo, Jeannette Hofmeijer, Jasper M Martens, Marianne AA van Walderveen, Bas FW van der Kallen, Sjoerd FM Jenniskens, Kilian M Treurniet, Henk A Marquering, Marieke ES Sprengers, Wouter J Schonewille, Joost CJ Bot, Geert J Lycklama a Nijeholt, Hester F Lingsma, David S Liebeskind, Jelis Boiten, Jan Albert Vos, Yvo BWEM Roos, Robert J van Oostenbrugge, Aad van der Lugt, Wim H van Zwam, Diederik WJ Dippel, Ido R van den Wijngaard, Charles BLM Majoie
    Journal of NeuroInterventional Surgery 2019 11 9
  • A meta‐analysis of collateral status and outcomes of mechanical thrombectomy
    Jiacheng Qian, Lu Fan, Weiqing Zhang, Jian Wang, Jianting Qiu, Yujie Wang
    Acta Neurologica Scandinavica 2020 142 3
  • Collateral state and the effect of endovascular reperfusion therapy on clinical outcome in ischemic stroke patients
    Johannes C. Gerber, Marketa Petrova, Pawel Krukowski, Matthias Kuhn, Andrij Abramyuk, Ulf Bodechtel, Imanuel Dzialowski, Kay Engellandt, Hagen Kitzler, Lars‐Peder Pallesen, Hauke Schneider, Ruediger von Kummer, Volker Puetz, Jennifer Linn
    Brain and Behavior 2016 6 9
  • Transcranial Doppler and Transcranial Color Duplex in Defining Collateral Cerebral Blood Flow
    Maher Saqqur, Khurshid Khan, Carol Derksen, Andrei Alexandrov, Ashfaq Shuaib
    Journal of Neuroimaging 2018 28 5
  • Prediction of favorable outcome by percent improvement in patients with acute ischemic stroke treated with endovascular stent thrombectomy
    Yuezhou Cao, Shuiping Wang, Wen Sun, Qiliang Dai, Wei Li, Jin Cai, Xinying Fan, Wusheng Zhu, Yunyun Xiong, Yunfei Han, Wenjie Zi, Shiquan Yang, Jia Chen, Xinfeng Liu
    Journal of Clinical Neuroscience 2017 38

More in this TOC Section

  • White Matter Alterations in the Brains of Patients with Active, Remitted, and Cured Cushing Syndrome: A DTI Study
  • Qualitative and Quantitative Analysis of MR Imaging Findings in Patients with Middle Cerebral Artery Stroke Implanted with Mesenchymal Stem Cells
  • Fast Contrast-Enhanced 4D MRA and 4D Flow MRI Using Constrained Reconstruction (HYPRFlow): Potential Applications for Brain Arteriovenous Malformations
Show more BRAIN

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • AJNR Awards
  • ASNR Foundation Special Collection
  • Most Impactful AJNR Articles
  • Photon-Counting CT
  • Spinal CSF Leak Articles (Jan 2020-June 2024)

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire