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Research ArticleInterventional

Fate of the Penumbra after Mechanical Thrombectomy

B. Friedrich, O. Kertels, D. Bach, S. Wunderlich, C. Zimmer, S. Prothmann and A. Förschler
American Journal of Neuroradiology May 2014, 35 (5) 972-977; DOI: https://doi.org/10.3174/ajnr.A3769
B. Friedrich
aFrom the Departments of Neuroradiology (B.F., O.K., D.B., C.Z., S.P., A.F.)
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O. Kertels
aFrom the Departments of Neuroradiology (B.F., O.K., D.B., C.Z., S.P., A.F.)
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D. Bach
aFrom the Departments of Neuroradiology (B.F., O.K., D.B., C.Z., S.P., A.F.)
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S. Wunderlich
bNeurology (S.W.), Klinikum Rechts der Isar, Munich, Germany.
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C. Zimmer
aFrom the Departments of Neuroradiology (B.F., O.K., D.B., C.Z., S.P., A.F.)
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S. Prothmann
aFrom the Departments of Neuroradiology (B.F., O.K., D.B., C.Z., S.P., A.F.)
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A. Förschler
aFrom the Departments of Neuroradiology (B.F., O.K., D.B., C.Z., S.P., A.F.)
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REFERENCES

  1. 1.↵
    1. Miniño AM,
    2. Murphy SL,
    3. Xu J,
    4. et al
    . Deaths: final data for 2008. Natl Vital Stat Rep 2011;59:1–126
    PubMed
  2. 2.↵
    1. Mullen MT,
    2. Pisapia JM,
    3. Tilwa S,
    4. et al
    . Systematic review of outcome after ischemic stroke due to anterior circulation occlusion treated with intravenous, intra-arterial, or combined intravenous + intra-arterial thrombolysis. Stroke 2012;43:2350–55
    Abstract/FREE Full Text
  3. 3.↵
    1. Pan F,
    2. Hernandez L,
    3. Ward A
    . Cost-effectiveness of stroke treatments and secondary preventions. Exp Opin Pharmacother 2012;13:1751–60
    CrossRefPubMed
  4. 4.↵
    1. Parsons MW,
    2. Pepper EM,
    3. Chan V,
    4. et al
    . Perfusion computed tomography: prediction of final infarct extent and stroke outcome. Ann Neurol 2005;58:672–79
    CrossRefPubMedWeb of Science
  5. 5.↵
    1. Wintermark M,
    2. Meuli R,
    3. Browaeys P,
    4. et al
    . Comparison of CT perfusion and angiography and MRI in selecting stroke patients for acute treatment. Neurology 2007;68:694–97
    CrossRef
  6. 6.↵
    1. Campbell BC,
    2. Weir L,
    3. Desmond PM,
    4. et al
    . CT perfusion improves diagnostic accuracy and confidence in acute ischaemic stroke. J Neurol Neurosurg Psychiatry 2013;84:613–18
    Abstract/FREE Full Text
  7. 7.↵
    1. Wahlgren N,
    2. Ahmed N,
    3. Dávalos A,
    4. et al
    . Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study. Lancet 2007;369:275–82
    CrossRefPubMedWeb of Science
  8. 8.↵
    1. Smith WS,
    2. Tsao JW,
    3. Billings ME,
    4. et al
    . Prognostic significance of angiographically confirmed large vessel intracranial occlusion in patients presenting with acute brain ischemia. Neurocrit Care 2006;4:14–17
    CrossRefPubMedWeb of Science
  9. 9.↵
    1. Abul-Kasim K,
    2. Brizzi M,
    3. Petersson J
    . Hyperdense middle cerebral artery sign is an ominous prognostic marker despite optimal workflow. Acta Neurol Scand 2010;122:132–39
    PubMedWeb of Science
  10. 10.↵
    1. Kharitonova T,
    2. Ahmed N,
    3. Thorén M,
    4. et al
    . Hyperdense middle cerebral artery sign on admission CT scan: prognostic significance for ischaemic stroke patients treated with intravenous thrombolysis in the safe implementation of thrombolysis in Stroke International Stroke Thrombolysis Register. Cerebrovasc Dis 2009;27:51–59
    CrossRefPubMed
  11. 11.↵
    1. Riedel CH,
    2. Zimmermann P,
    3. Jensen-Kondering U,
    4. et al
    . The importance of size: successful recanalization by intravenous thrombolysis in acute anterior stroke depends on thrombus length. Stroke 2011;42:1775–77
    Abstract/FREE Full Text
  12. 12.↵
    1. de Los Ríos la Rosa F,
    2. Khoury J,
    3. Kissela BM,
    4. et al
    . Eligibility for intravenous recombinant tissue-type plasminogen activator within a population: the effect of the European Cooperative Acute Stroke Study (ECASS) III Trial. Stroke 2012;43:1591–95
    Abstract/FREE Full Text
  13. 13.↵
    1. Smith WS,
    2. Sung G,
    3. Starkman S,
    4. et al
    . Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke 2005;36:1432–38
    Abstract/FREE Full Text
  14. 14.↵
    1. Smith WS,
    2. Sung G,
    3. Saver J,
    4. et al
    . Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial. Stroke 2008;39:1205–12
    Abstract/FREE Full Text
  15. 15.↵
    1. Grunwald IQ,
    2. Walter S,
    3. Papanagiotou P,
    4. et al
    . Revascularization in acute ischaemic stroke using the Penumbra system: the first single center experience. Eur J Neurol 2009;16:1210–16
    CrossRefPubMedWeb of Science
  16. 16.↵
    Penumbra Pivotal Stroke Trial Investigators. The Penumbra Pivotal Stroke Trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease. Stroke 2009;40:2761–68
    Abstract/FREE Full Text
  17. 17.↵
    1. Machi P,
    2. Costalat V,
    3. Lobotesis K,
    4. et al
    . Solitaire FR thrombectomy system: immediate results in 56 consecutive acute ischemic stroke patients. J Neurointerv Surg 2012;4:62–66
    Abstract/FREE Full Text
  18. 18.↵
    1. Mokin M,
    2. Dumont TM,
    3. Veznedaroglu E,
    4. et al
    . Solitaire flow restoration thrombectomy for acute ischemic stroke: retrospective multicenter analysis of early postmarket experience after FDA approval. Neurosurgery 2013;73:19–26
    CrossRefPubMedWeb of Science
  19. 19.↵
    1. Ribo M,
    2. Molina CA,
    3. Jankowitz B,
    4. et al
    . Stentrievers versus other endovascular treatment methods for acute stroke: comparison of procedural results and their relationship to outcomes. J Neurointerv Surg 2014;6:265–69
    Abstract/FREE Full Text
  20. 20.↵
    1. Broussalis E,
    2. Trinka E,
    3. Hitzl W,
    4. et al
    . Comparison of stent-retriever devices versus the Merci retriever for endovascular treatment of acute stroke. AJNR Am J Neuroradiol 2013;34:366–72
    Abstract/FREE Full Text
  21. 21.↵
    1. Wintermark M,
    2. Flanders AE,
    3. Velthuis B,
    4. et al
    . Perfusion-CT assessment of infarct core and penumbra: receiver operating characteristic curve analysis in 130 patients suspected of acute hemispheric stroke. Stroke 2006;37:979–85
    Abstract/FREE Full Text
  22. 22.↵
    1. Dorn F,
    2. Stehle S,
    3. Lockau H,
    4. et al
    . Endovascular treatment of acute intracerebral artery occlusions with the Solitaire stent: single-centre experience with 108 recanalization procedures. Cerebrovasc Dis 2012;34:70–77
    CrossRefPubMed
  23. 23.↵
    1. Prothmann S,
    2. Lockau H,
    3. Dorn F,
    4. et al
    . The Phenox clot retriever as part of a multimodal mechanical thrombectomy approach in acute ischemic stroke: single center experience in 56 patients. Sci World J 2012;2012:190763.
  24. 24.↵
    1. Barber PA,
    2. Demchuk AM,
    3. Zhang J,
    4. et al
    . Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. ASPECTS Study Group. Alberta Stroke Programme Early CT Score. Lancet 2000;355:1670–74
    CrossRefPubMedWeb of Science
  25. 25.↵
    1. Astrup J,
    2. Symon L,
    3. Branston NM,
    4. et al
    . Cortical evoked potential and extracellular K+ and H+ at critical levels of brain ischemia. Stroke 1977;8:51–57
    Abstract/FREE Full Text
  26. 26.↵
    1. Broderick JP,
    2. Palesch YY,
    3. Demchuk AM,
    4. et al
    . Endovascular therapy after intravenous t-PA versus t-PA alone for stroke. N Engl J Med 2013;368:893–903
    CrossRefPubMedWeb of Science
  27. 27.↵
    1. Kidwell CS,
    2. Jahan R,
    3. Gornbein J,
    4. et al
    . A trial of imaging selection and endovascular treatment for ischemic stroke. N Engl J Med 2013;368:914–23
    CrossRefPubMedWeb of Science
  28. 28.↵
    1. Saver JL,
    2. Jahan R,
    3. Levy EI,
    4. et al
    . Solitaire flow restoration device versus the Merci retriever in patients with acute ischaemic stroke (SWIFT): a randomised, parallel-group, non-inferiority trial. Lancet 2012;380:1241–49
    CrossRefPubMedWeb of Science
  29. 29.↵
    1. Hassan AE,
    2. Chaudhry SA,
    3. Miley JT,
    4. et al
    . Microcatheter to recanalization (procedure time) predicts outcomes in endovascular treatment in patients with acute ischemic stroke: when do we stop? AJNR Am J Neuroradiol 2013;34:354–59
    Abstract/FREE Full Text
  30. 30.↵
    1. Parsons M,
    2. Spratt N,
    3. Bivard A,
    4. et al
    . A randomized trial of tenecteplase versus alteplase for acute ischemic stroke. N Engl J Med 2012;366:1099–107
    CrossRefPubMedWeb of Science
  31. 31.↵
    1. Barber PA,
    2. Hill MD,
    3. Eliasziw M,
    4. et al
    . Imaging of the brain in acute ischaemic stroke: comparison of computed tomography and magnetic resonance diffusion-weighted imaging. J Neurol Neurosurg Psychiatry 2005;76:1528–33
    Abstract/FREE Full Text
  32. 32.↵
    1. Zaidi SF,
    2. Aghaebrahim A,
    3. Urra X,
    4. et al
    . Final infarct volume is a stronger predictor of outcome than recanalization in patients with proximal middle cerebral artery occlusion treated with endovascular therapy. Stroke 2012;43:3238–44
    Abstract/FREE Full Text
  33. 33.↵
    1. Yoo AJ,
    2. Chaudhry ZA,
    3. Nogueira RG,
    4. et al
    . Infarct volume is a pivotal biomarker after intra-arterial stroke therapy. Stroke 2012;43:1323–30
    Abstract/FREE Full Text
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Cite this article
B. Friedrich, O. Kertels, D. Bach, S. Wunderlich, C. Zimmer, S. Prothmann, A. Förschler
Fate of the Penumbra after Mechanical Thrombectomy
American Journal of Neuroradiology May 2014, 35 (5) 972-977; DOI: 10.3174/ajnr.A3769

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Fate of the Penumbra after Mechanical Thrombectomy
B. Friedrich, O. Kertels, D. Bach, S. Wunderlich, C. Zimmer, S. Prothmann, A. Förschler
American Journal of Neuroradiology May 2014, 35 (5) 972-977; DOI: 10.3174/ajnr.A3769
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  • An Observational Study Investigating the Need for Decompressive Hemicraniectomy after Thrombectomy in Acute Ischemic Stroke of the Middle Cerebral Artery Territory
    Arsalaan Salehani, Borna E Tabibian, D M Self, Bonita Agee, Gustavo Chagoya, William Stetler, Winfield S Fisher
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  • Core and penumbra estimation using deep learning-based AIF in association with clinical measures in computed tomography perfusion (CTP)
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More in this TOC Section

  • SAVE vs. Solumbra Techniques for Thrombectomy
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  • CT Perfusion&Reperfusion in Acute Ischemic Stroke
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