Article Figures & Data
Tables
- Table 1:
Univariable analysis of characteristics associated with perfusion imaging selection
Perfusion Selection (n = 76) NCCT Selection (n = 138) P Value Age (yr) <.001 Mean (SD) 72.4 (14.1) 64.4 (16.3) Male, No. (%) 26 (34.2) 61 (44.2) .154 Onset to arrival time (min) .520 Median (IQR) 245 (123.5–300.0) 241.5 (180.0–320.0) Initial NIHSS score .018 Median (IQR) 18 (13–20) 19 (16–22) Initial THRIVE score .529 Median (IQR) 4 (3–5) 4.5 (3–6) IV tPA prior to ERT, No. (%) 31 (40.8) 67 (48.6) .275 Location of occlusion, No. (%) <.001 Middle cerebral artery 68 (89.5) 91 (65.9) Internal carotid artery 8 (10.5) 47 (34.1) Mode of IA therapy .028 Lytic only 3 (3.8) 0 Mechanical only 44 (57.9) 95 (68.8) Lytic + mechanical 29 (38.2) 43 (31.2) Onset-to-GP time in minutes .366 Median (IQR) 348 (225.75–399.75) 309 (245.5–375.0) Symptomatic hemorrhage, No. (%) 4 (5.3) 17 (12.3) .148 TICI 2b/3 reperfusion, No. (%) 46 (62.5) 65 (47.1) .036 Year .215 2007 4 (5.3) 15 (10.9) 2008 9 (11.8) 22 (15.9) 2009 18 (23.7) 29 (21.0) 2010 17 (22.4) 35 (25.4) 2011 15 (19.7) 27 (19.6) 2012 13 (17.1) 10 (7.2) Note:—IQR indicates interquartile range; IA, intra-arterial; GP, groin puncture.
- Table 2:
Univariable analysis of characteristics associated with good outcome (mRS 0–2) at 3 months
Good Outcome (n = 88) Poor Outcome (n = 126) P Value Age (yr) .891 Mean (SD) 67.0 (15.6) 67.4 (16.3) Male, No. (%) 36 (40.5) 51 (40.9) .949 Onset-to-arrival time in minutes .627 Median (IQR) 240 (139.0–304.5) 250 (178.5–366.0) Initial NIHSS score .009 Median (IQR) 18 (12.25–21.0) 19 (16–22) Initial THRIVE score .004 Median (IQR) 4 (3–5) 5 (4–6) IV tPA prior to ERT, No. (%) 49 (55.7) 49 (38.9) .015 Location of occlusion, No. (%) .607 Middle cerebral artery 67 (76.1) 92 (73.0) Internal carotid artery 21 (23.9) 34 (27.0) Mode of ERT .488 Lytic only 2 (2.3) 1 (0.8) Mechanical only 54 (61.4) 85 (67.5) Lytic + mechanical 32 (44.4) 40 (31.7) Onset to GP time in minutes .790 Median (IQR) 306.5 (240.0–385.0) 315 (242.75–379.75) Symptomatic hemorrhage, No. (%) 3 (3.4) 18 (14.3) .009 TICI 2b/3 reperfusion, No. (%) 64 (72.7) 47 (37.9) <.001 Year .147 2007 7 (8.0) 12 (9.5) 2008 10 (11.4) 21 (9.8) 2009 21 (23.9) 26 (20.6) 2010 29 (33.0) 23 (18.3) 2011 13 (14.0) 29 (23.0) 2012 8 (9.1) 15 (11.9) Note:—IQR indicates interquartile range; GP, groin puncture.
- Table 3:
Multivariable model for good outcome (mRS 0–2 at 3 months) with the following dependent variables: age, calendar year, initial NIHSS score, IV tPA use, selection mode, location of occlusion, mode of therapy, final TICI score, and symptomatic hemorrhagea
Adjusted OR 95% CI P Value Selection mode .010 NCCT only (reference) – – Perfusion imaging 2.34 1.23–4.47 Initial NIHSS score (per point) 0.92 0.87–0.98 .006 IV tPA prior to IAT 2.12 1.13–3.96 .019 TICI score <.001 TICI <2b (reference) – – TICI 2b or 3 4.26 2.27–8.03 Note:—IQR indicates interquartile range; IAT, intra-arterial therapy.
↵a Hosmer-Lemeshow test for goodness of fit: P = .229.