Article Figures & Data
Figures
- Fig 1.
Individual test results of VerifyNow (A), the Multiplate (B), and LTA (C). The line parallel to the x-axis marks the particular cutoff value that has been used to discriminate between clopidogrel resistance and clopidogrel response. Procedures in which an embolic complication occurred are indicated by plus signs. Embolic complications Nr.53 and Nr.54 occurred in a single patient with 2 subsequent treatments of a symptomatic ICA and vertebral artery stenosis, respectively. PRU indicates P2Y12 reaction units; MA, maximal aggregation; AUC, area under the curve.
- Fig 2.
Correlation scatterplots of individual results obtained with VerifyNow versus the Multiplate (A), the Multiplate versus LTA (B), and VerifyNow versus LTA (C). Lines parallel to the axes mark the particular cutoff values. The upper-right and lower-left quadrants contain values with agreement in regard to the definition of clopidogrel resistance. Procedures in which an embolic complication occurred are indicated by plus signs.
Tables
Clopidogrel Status n % Resistant according to: ≥1 method 69 67 ≥2 methods 43 41.9 All 3 methods 24 23.3 Clopidogrel responsive according to all 3 methods 34 33 Method Total (n) No Complications (n [%]) Thromboembolic Complication (n [%]) P Value VerifyNow Resistant 52 46 88.4 6 11.5 .6413 Responsive 51 48 94.1 3 5.9 Multiplate Resistant 35 31 88.6 4 11.4 .5816 Responsive 68 63 92.7 5 7.5 LTA Resistant 49 42 85.7 7 14.3 .0938 Responsive 54 52 96.3 2 3.7 Method Sensitivity (%) Specificity (%) Positive Predictive Value (%) Negative Predictive Value (%) VerifyNow 66.7 51.1 11.5 94.1 Multiplate 44.4 67.0 11.4 92.7 LTA 77.8 55.3 14.3 96.3
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