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Research ArticleINTERVENTIONAL
Open Access

WEB-DL Endovascular Treatment of Wide-Neck Bifurcation Aneurysms: Long-Term Results in a European Series

L. Pierot, J. Klisch, T. Liebig, J.-Y. Gauvrit, M. Leonardi, N.P. Nuzzi, F. Di Paola, V. Sychra, B. Mine and B. Lubicz
American Journal of Neuroradiology December 2015, 36 (12) 2314-2319; DOI: https://doi.org/10.3174/ajnr.A4445
L. Pierot
aFrom the Department of Neuroradiology (L.P.), Hôpital Maison-Blanche, Université Reims-Champagne-Ardenne, Reims, France
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J. Klisch
bDepartment of Diagnostic and Interventional Radiology and Neuroradiology (J.K., V.S.), Helios General Hospital, Erfurt, Germany
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T. Liebig
cDepartment of Neuroradiology (T.L.), Universitätsklinikum Köln, Cologne, Germany
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  • ORCID record for T. Liebig
J.-Y. Gauvrit
dDepartment of Neuroradiology (J.-Y.G.), CHU Rennes, Rennes, France
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M. Leonardi
eDepartment of Neuroradiology (M.L.), Ospedale Bellaria, Bologna University, Bologna, Italy
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N.P. Nuzzi
fDepartment of Neuroradiology (N.P.N.), Ospedale Galliera, Genova, Italy
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F. Di Paola
gDepartment of Neuroradiology (F.D.P.), Ospedale Santa Maria, Treviso, Italy
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V. Sychra
bDepartment of Diagnostic and Interventional Radiology and Neuroradiology (J.K., V.S.), Helios General Hospital, Erfurt, Germany
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B. Mine
hDepartment of Neuroradiology (B.M., B.L.), Erasme University Hospital, Brussels, Belgium.
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B. Lubicz
hDepartment of Neuroradiology (B.M., B.L.), Erasme University Hospital, Brussels, Belgium.
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This article has a correction. Please see:

  • Erratum - February 01, 2016

Abstract

BACKGROUND AND PURPOSE: Flow disruption with the WEB-DL device has been used safely for the treatment of wide-neck bifurcation aneurysms. The stability of aneurysm occlusion after this treatment was evaluated in the short and midterm, but not in the long term. This retrospective multicenter European study is the continuation of an already published series dealing with short- and midterm anatomic results and analyzes long-term data in patients treated with the WEB-DL.

MATERIALS AND METHODS: Twelve European neurointerventional centers initially participated in the study. In addition to data collected for the initial publication, images obtained at long-term follow-up were collected and independently analyzed by the same experienced interventional neuroradiologist.

RESULTS: Of the initial 45 patients, 26 (20 women and 6 men; 35–73 years of age; mean, 55.2 ± 10.6 years; median, 55.5 years) with 26 aneurysms treated with the WEB-DL device had long-term follow-up (median, 27.4 months). Three of 26 patients (11.5%) were retreated between short- and midterm follow-up, and none, between mid- and long-term follow-up. Long-term aneurysm occlusion in the 19 patients treated with the WEB only and not retreated during follow-up was complete occlusion in 13/19 patients (68.4%), including aneurysms with opacification of the proximal recess in 9/19 patients (47.4%), neck remnant in 3/19 patients (15.8%), and aneurysm remnant in 3/19 patients (15.8%). In all patients (100.0%), aneurysm occlusion was stable between midterm and long-term follow-up.

CONCLUSIONS: The results suggest that WEB treatment of wide-neck bifurcation aneurysms offers long-term stable occlusion.

ABBREVIATIONS:

DL
Dual Layer
WEBCAST
WEB Clinical Assessment of IntraSaccular Aneurysm Therapy
  • © 2015 by American Journal of Neuroradiology

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American Journal of Neuroradiology: 36 (12)
American Journal of Neuroradiology
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1 Dec 2015
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Cite this article
L. Pierot, J. Klisch, T. Liebig, J.-Y. Gauvrit, M. Leonardi, N.P. Nuzzi, F. Di Paola, V. Sychra, B. Mine, B. Lubicz
WEB-DL Endovascular Treatment of Wide-Neck Bifurcation Aneurysms: Long-Term Results in a European Series
American Journal of Neuroradiology Dec 2015, 36 (12) 2314-2319; DOI: 10.3174/ajnr.A4445

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WEB-DL Endovascular Treatment of Wide-Neck Bifurcation Aneurysms: Long-Term Results in a European Series
L. Pierot, J. Klisch, T. Liebig, J.-Y. Gauvrit, M. Leonardi, N.P. Nuzzi, F. Di Paola, V. Sychra, B. Mine, B. Lubicz
American Journal of Neuroradiology Dec 2015, 36 (12) 2314-2319; DOI: 10.3174/ajnr.A4445
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