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Research ArticleHead & Neck

Prognostic Value of Labyrinthine 3D-FLAIR Abnormalities in Idiopathic Sudden Sensorineural Hearing Loss

J.I. Lee, R.G. Yoon, J.H. Lee, J.W. Park, M.H. Yoo, J.H. Ahn, J.W. Chung and H.J. Park
American Journal of Neuroradiology December 2016, 37 (12) 2317-2322; DOI: https://doi.org/10.3174/ajnr.A4901
J.I. Lee
aFrom the Departments of Otolaryngology (J.I.L., J.W.P., J.H.A., J.W.C., H.J.P.)
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R.G. Yoon
cDepartment of Radiology (R.G.Y.), Catholic Kwandong University International St. Mary's Hospital, Catholic Kwandong University College of Medicine, Incheon, Korea
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J.H. Lee
bRadiology (J.H.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
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J.W. Park
aFrom the Departments of Otolaryngology (J.I.L., J.W.P., J.H.A., J.W.C., H.J.P.)
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M.H. Yoo
dDepartment of Otolaryngology (M.H.Y.), College of Medicine, Kyungpook National University, Daegu, Korea.
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J.H. Ahn
aFrom the Departments of Otolaryngology (J.I.L., J.W.P., J.H.A., J.W.C., H.J.P.)
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J.W. Chung
aFrom the Departments of Otolaryngology (J.I.L., J.W.P., J.H.A., J.W.C., H.J.P.)
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H.J. Park
aFrom the Departments of Otolaryngology (J.I.L., J.W.P., J.H.A., J.W.C., H.J.P.)
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Article Figures & Data

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    Fig 1.

    Study population excluded and enrolled in this study.

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    Fig 2.

    Precontrast axial scans of 3D-FLAIR MR imaging in right inner ear of a 63-year-old man with right sudden sensorineural hearing loss with vertigo. Bright signals (arrows) are visible only in the right cochlea and vestibule at the level of the basal turn (A) and midturn (B) of the cochlea and vestibule, not in the left healthy cochlea and vestibule (open arrows).

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    Fig 3.

    Hearing improvement according to the Siegel criteria in the MRI+ and MRI− groups. CR indicates complete recovery; PR, partial recovery; SI, slight improvement; NR, no recovery.

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    Fig 4.

    Initial pretreatment and final posttreatment audiologic findings and the improvement of hearing (ΔPTA) in the MRI− and MRI+ groups according to the initial hearing loss. ΔPTA indicates the difference of mean pre- and posttreatment.

Tables

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    Table 1:

    Clinical and demographic characteristics of patients with SSNHL

    All (N = 113)MRI− Group (n = 82)MRI+ Group (n = 31)P Value
    Mean age (yr)53 ± 1453 ± 1455 ± 14.634
    Sex (male/female)51:6238:4413:18.675
    DM (No.) (%)11 (10)7 (9)4 (13).490
    HTN (No.) (%)27 (24)20 (24)7 (23).840
    Vertigo (No.) (%)30 (27)21 (26)9 (29).713
    Tinnitus (No.) (%)82 (73)61 (74)21 (68).480
    Ear fullness (No.) (%)53 (47)39 (48)14 (45).820
    Initial visit after onset (days)7 ± 107 ± 109 ± 9.076
    MRI after onset (days)10 ± 810 ± 89 ± 6.804
    ITSI before MRI (No.) (%)16 (14)11 (13)5 (16).713
    • Note:—DM indicates diabetes mellitus; HTN, hypertension; ITSI, intratympanic steroid injection.

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    Table 2:

    Initial and final audiologic results and classification by Siegel criteria in MRI+ and MRI− groups

    All Cases (N = 113)MRI− Group (n = 82)MRI+ Group (n = 31)P Value
    Initial audiogram (mean) (dB HL)75 ± 3069 ± 3091 ± 25<.001
    Severity of initial HL (No.) (%).005
        Mild16 (14)15 (18)1 (3)
        Moderate24 (21)22 (27)2 (6)
        Moderately severe15 (13)10 (12)5 (16)
        Severe24 (21)17 (21)7 (23)
        Profound34 (30)18 (22)16 (52)
    Additional ITSI (No.) (%)79 (70)50 (61)29 (94).001
    Final audiogram (mean (dB HL)55 ± 2748 ± 2473 ± 27<.001
    Improvement of hearing (ΔPTA, dB)20 ± 2421 ± 2318 ± 24.964
    Improvement by Siegel criteria (No.) (%).003
        No improvement50 (44)38 (46)12 (39)
        Slight improvement32 (28)16 (20)16 (52)
        Partial recovery18 (16)17 (21)1 (3)
        Complete recovery13 (12)11 (13)2 (6)
    • Note:—ΔPTA indicates difference of mean pre- and posttreatment PTA; ITSI, intratympanic steroid injection.

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American Journal of Neuroradiology: 37 (12)
American Journal of Neuroradiology
Vol. 37, Issue 12
1 Dec 2016
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Cite this article
J.I. Lee, R.G. Yoon, J.H. Lee, J.W. Park, M.H. Yoo, J.H. Ahn, J.W. Chung, H.J. Park
Prognostic Value of Labyrinthine 3D-FLAIR Abnormalities in Idiopathic Sudden Sensorineural Hearing Loss
American Journal of Neuroradiology Dec 2016, 37 (12) 2317-2322; DOI: 10.3174/ajnr.A4901

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Prognostic Value of Labyrinthine 3D-FLAIR Abnormalities in Idiopathic Sudden Sensorineural Hearing Loss
J.I. Lee, R.G. Yoon, J.H. Lee, J.W. Park, M.H. Yoo, J.H. Ahn, J.W. Chung, H.J. Park
American Journal of Neuroradiology Dec 2016, 37 (12) 2317-2322; DOI: 10.3174/ajnr.A4901
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