Age- and Level-Dependence of Fatty Infiltration in Lumbar Paravertebral Muscles of Healthy Volunteers

REFERENCES

1. 1.↵
   2. Akagi R,
   3. Takai Y,
   4. Kato E, et al

   . Development of an equation to predict muscle volume of elbow flexors for men and women with a wide range of age. Eur J Appl Physiol 2010;108:689–94 doi:10.1007/s00421-009-1269-1 pmid:19904555

   CrossRefPubMed
2. 2.↵
   2. Samagh SP,
   3. Kramer EJ,
   4. Melkus G, et al

   . MRI quantification of fatty infiltration and muscle atrophy in a mouse model of rotator cuff tears. J Orthop Res 2013;31:421–26 doi:10.1002/jor.22233 pmid:22991068

   CrossRefPubMed
3. 3.↵
   2. Elliott JM,
   3. Flynn TW,
   4. Al-Najjar A, et al

   . The pearls and pitfalls of magnetic resonance imaging for the spine. J Orthop Sports Phys Ther 2011;41:848–60 doi:10.2519/jospt.2011.3636 pmid:22048067

   CrossRefPubMed
4. 4.↵
   2. Elliott JM,
   3. O'Leary S,
   4. Sterling M, et al

   . Magnetic resonance imaging findings of fatty infiltrate in the cervical flexors in chronic whiplash. Spine 2010;35:948–54 doi:10.1097/BRS.0b013e3181bb0e55 pmid:20118837

   CrossRefPubMed
5. 5.↵
   2. Fischer MA,
   3. Nanz D,
   4. Shimakawa A, et al

   . Quantification of muscle fat in patients with low back pain: comparison of multi-echo MR imaging with single-voxel MR spectroscopy. Radiology 2013;266:555–63 doi:10.1148/radiol.12120399 pmid:23143025

   CrossRefPubMed
6. 6.↵
   2. Reeder SB,
   3. Hu HH,
   4. Sirlin CB

   . Proton density fat-fraction: a standardized MR-based biomarker of tissue fat concentration. J Magn Reson Imaging 2012;36:1011–14 doi:10.1002/jmri.23741 pmid:22777847

   CrossRefPubMed
7. 7.↵
   2. Elliott J,
   3. Pedler A,
   4. Kenardy J, et al

   . The temporal development of fatty infiltrates in the neck muscles following whiplash injury: an association with pain and posttraumatic stress. PLoS One 2011;6:e21194 doi:10.1371/journal.pone.0021194 pmid:21698170

   CrossRefPubMed
8. 8.↵
   2. Fischer MA,
   3. Pfirrmann CW,
   4. Espinosa N, et al

   . Dixon-based MRI for assessment of muscle-fat content in phantoms, healthy volunteers and patients with achillodynia: comparison to visual assessment of calf muscle quality. Eur Radiol 2014;24:1366–75 doi:10.1007/s00330-014-3121-1 pmid:24604216

   CrossRefPubMed
9. 9.↵
   2. Smith AC,
   3. Parrish TB,
   4. Abbott R, et al

   . Muscle-fat MRI: 1.5 Tesla and 3.0 Tesla versus histology. Muscle Nerve 2014;50:170–76 doi:10.1002/mus.24255 pmid:24677256

   CrossRefPubMed
10. 10.↵
    2. Dixon WT

    . Simple proton spectroscopic imaging. Radiology 1984;153:189–94 doi:10.1148/radiology.153.1.6089263 pmid:6089263

    CrossRefPubMedWeb of Science
11. 11.↵
    2. Ma J

    . Dixon techniques for water and fat imaging. J Magn Reson Imaging 2008;28:543–58 doi:10.1002/jmri.21492 pmid:18777528

    CrossRefPubMedWeb of Science
12. 12.↵
    2. Elliott JM,
    3. Walton DM,
    4. Rademaker A, et al

    . Quantification of cervical spine muscle fat: a comparison between T1-weighted and multi-echo gradient echo imaging using a variable projection algorithm (VARPRO). BMC Med Imag 2013;13:30 doi:10.1186/1471-2342-13-30 pmid:24020963

    CrossRefPubMed
13. 13.↵
    2. Paalanne N,
    3. Niinimaki J,
    4. Karppinen J, et al

    . Assessment of association between low back pain and paraspinal muscle atrophy using opposed-phase magnetic resonance imaging: a population-based study among young adults. Spine 2011;36:1961–68 doi:10.1097/BRS.0b013e3181fef890 pmid:21289551

    CrossRefPubMedWeb of Science
14. 14.↵
    2. Elliott JM,
    3. Courtney DM,
    4. Rademaker A, et al

    . The rapid and progressive degeneration of the cervical multifidus in whiplash: a MRI study of fatty infiltration. Spine (Phila Pa 1976) 2015;40:E694–700 doi:10.1097/BRS.0000000000000891 pmid:25785961

    CrossRefPubMed
15. 15.↵
    2. Gaeta M,
    3. Scribano E,
    4. Mileto A, et al

    . Muscle fat fraction in neuromuscular disorders: dual-echo dual-flip-angle spoiled gradient-recalled MR imaging technique for quantification—a feasibility study. Radiology 2011;259:487–94 doi:10.1148/radiol.10101108 pmid:21324839

    CrossRefPubMed
16. 16.↵
    2. Danneels LA,
    3. Vanderstraeten GG,
    4. Cambier DC, et al

    . CT imaging of trunk muscles in chronic low back pain patients and healthy control subjects. Eur Spine J 2000;9:266–72 doi:10.1007/s005860000190 pmid:11261613

    CrossRefPubMedWeb of Science
17. 17.↵
    2. Fortin M,
    3. Videman T,
    4. Gibbons LE, et al

    . Paraspinal muscle morphology and composition: a 15-yr longitudinal magnetic resonance imaging study. Med Sci Sports Exerc 2014;46:893–901 doi:10.1249/MSS.0000000000000179 pmid:24091994

    CrossRefPubMed
18. 18.↵
    2. Fortin M,
    3. Yuan Y,
    4. Battié MC

    . Factors associated with paraspinal muscle asymmetry in size and composition in a general population sample of men. Phys Ther 2013;93:1540–50 doi:10.2522/ptj.20130051 pmid:23813083

    Abstract/FREE Full Text
19. 19.↵
    2. Hides J,
    3. Gilmore C,
    4. Stanton W, et al

    . Multifidus size and symmetry among chronic LBP and healthy asymptomatic subjects. Man Ther 2008;13:43–49 doi:10.1016/j.math.2006.07.017 pmid:17070721

    CrossRefPubMedWeb of Science
20. 20.↵
    2. Ploumis A,
    3. Michailidis N,
    4. Christodoulou P, et al

    . Ipsilateral atrophy of paraspinal and psoas muscle in unilateral back pain patients with monosegmental degenerative disc disease. Br J Radiol 2011;84:709–13 doi:10.1259/bjr/58136533 pmid:21081573

    Abstract/FREE Full Text
21. 21.↵
    2. Teichtahl AJ,
    3. Urquhart DM,
    4. Wang Y, et al

    . Fat infiltration of paraspinal muscles is associated with low back pain, disability, and structural abnormalities in community-based adults. Spine J 2015;15:1593–601 doi:10.1016/j.spinee.2015.03.039 pmid:25828477

    CrossRefPubMed
22. 22.↵
    2. Hodges P,
    3. Holm AK,
    4. Hansson T, et al

    . Rapid atrophy of the lumbar multifidus follows experimental disc or nerve root injury. Spine 2006;31:2926–33 doi:10.1097/01.brs.0000248453.51165.0b pmid:17139223

    CrossRefPubMedWeb of Science
23. 23.↵
    2. Farshad M,
    3. Gerber C,
    4. Farshad-Amacker NA, et al

    . Asymmetry of the multifidus muscle in lumbar radicular nerve compression. Skeletal Radiol 2014;43:49–53 doi:10.1007/s00256-013-1748-7 pmid:24170037

    CrossRefPubMed
24. 24.↵
    2. Kjaer P,
    3. Bendix T,
    4. Sorensen JS, et al

    . Are MRI-defined fat infiltrations in the multifidus muscles associated with low back pain? BMC Med 2007;5:2 doi:10.1186/1741-7015-5-2 pmid:17254322

    CrossRefPubMed
25. 25.↵
    2. Mengiardi B,
    3. Schmid MR,
    4. Boos N, et al

    . Fat content of lumbar paraspinal muscles in patients with chronic low back pain and in asymptomatic volunteers: quantification with MR spectroscopy. Radiology 2006;240:786–92 doi:10.1148/radiol.2403050820 pmid:16926328

    CrossRefPubMedWeb of Science
26. 26.↵
    2. Parkkola R,
    3. Rytökoski U,
    4. Kormano M

    . Magnetic resonance imaging of the discs and trunk muscles in patients with chronic low back pain and healthy control subjects. Spine 1993;18:830–36 doi:10.1097/00007632-199306000-00004 pmid:8316880

    CrossRefPubMedWeb of Science
27. 27.↵
    2. Barker KL,
    3. Shamley DR,
    4. Jackson D

    . Changes in the cross-sectional area of multifidus and psoas in patients with unilateral back pain: the relationship to pain and disability. Spine 2004;29:E515–19 doi:10.1097/01.brs.0000144405.11661.eb pmid:15543053

    CrossRefPubMedWeb of Science
28. 28.↵
    2. Meakin JR,
    3. Fulford J,
    4. Seymour R, et al

    . The relationship between sagittal curvature and extensor muscle volume in the lumbar spine. J Anat 2013;222:608–14 doi:10.1111/joa.12047 pmid:23600615

    CrossRefPubMed
29. 29.↵
    2. Valentin S,
    3. Licka T,
    4. Elliott J

    . Age and side-related morphometric MRI evaluation of trunk muscles in people without back pain. Man Ther 2015;20:90–95 doi:10.1016/j.math.2014.07.007 pmid:25085813

    CrossRefPubMed
30. 30.↵
    2. Brinjikji W,
    3. Luetmer PH,
    4. Comstock B, et al

    . Systematic literature review of imaging features of spinal degeneration in asymptomatic populations. AJNR Am J Neuroradiol 2015;36:811–16 doi:10.3174/ajnr.A4173 pmid:25430861

    Abstract/FREE Full Text
31. 31.↵
    Obesity: preventing and managing the global epidemic: report of a WHO consultation. World Health Organ Tech Rep Ser 2000;894:i–xii, 1–253 pmid:11234459

    PubMed
32. 32.↵
    2. Hoffman M,
    3. Schrader J,
    4. Applegate T, et al

    . Unilateral postural control of the functionally dominant and nondominant extremities of healthy subjects. J Athl Train 1998;33:319–22 pmid:16558528

    PubMedWeb of Science
33. 33.↵
    2. Cassidy FH,
    3. Yokoo T,
    4. Aganovic L, et al

    . Fatty liver disease: MR imaging techniques for the detection and quantification of liver steatosis. Radiographics 2009;29:231–60 doi:10.1148/rg.291075123 pmid:19168847

    CrossRefPubMedWeb of Science
34. 34.↵
    2. D'Hooge R,
    3. Cagnie B,
    4. Crombez G, et al

    . Increased intramuscular fatty infiltration without differences in lumbar muscle cross-sectional area during remission of unilateral recurrent low back pain. Man Ther 2012;17:584–88 doi:10.1016/j.math.2012.06.007 pmid:22784801

    CrossRefPubMed
35. 35.↵
    2. Been E,
    3. Kalichman L

    . Lumbar lordosis. Spine J 2014;14:87–97 doi:10.1016/j.spinee.2013.07.464 pmid:24095099

    CrossRefPubMed
36. 36.↵
    2. Tong HC,
    3. Haig AJ,
    4. Yamakawa KS, et al

    . Paraspinal electromyography: age-correlated normative values in asymptomatic subjects. Spine 2005;30:E499–502 doi:10.1097/01.brs.0000176318.95523.12 pmid:16135972

    CrossRefPubMed
37. 37.↵
    2. Haig AJ,
    3. London Z,
    4. Sandella DE

    . Symmetry of paraspinal muscle denervation in clinical lumbar spinal stenosis: support for a hypothesis of posterior primary ramus stretching? Muscle Nerve 2013;48:198–203 doi:10.1002/mus.23750 pmid:23813584

    CrossRefPubMed
38. 38.↵
    2. Yarjanian JA,
    3. Fetzer A,
    4. Yamakawa KS, et al

    . Correlation of paraspinal atrophy and denervation in back pain and spinal stenosis relative to asymptomatic controls. PM R 2013;5:39–44 doi:10.1016/j.pmrj.2012.08.017 pmid:23332908

    CrossRefPubMed
39. 39.↵
    2. Abbott R,
    3. Pedler A,
    4. Sterling M, et al

    . The geography of fatty infiltrates within the cervical multifidus and semispinalis cervicis in individuals with chronic whiplash-associated disorders. J Orthop Sports Phys Ther 2015;45:281–88 doi:10.2519/jospt.2015.5719 pmid:25739843

    CrossRefPubMed
40. 40.↵
    2. Niemelainen R,
    3. Briand MM,
    4. Battié MC

    . Substantial asymmetry in paraspinal muscle cross-sectional area in healthy adults questions its value as a marker of low back pain and pathology. Spine 2011;36:2152–57 doi:10.1097/BRS.0b013e318204b05a pmid:21343855

    CrossRefPubMedWeb of Science
41. 41.↵
    2. Doherty TJ

    . Invited review: aging and sarcopenia. J Appl Physiol 2003;95:1717–27 doi:10.1152/japplphysiol.00347.2003 pmid:12970377

    Abstract/FREE Full Text
42. 42.↵
    2. Sillanpää E,
    3. Cheng S,
    4. Häkkinen K, et al

    . Body composition in 18- to 88-year-old adults–comparison of multifrequency bioimpedance and dual-energy X-ray absorptiometry. Obesity 2014;22:101–09 doi:10.1002/oby.20583 pmid:23894111

    CrossRefPubMed