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Research ArticleINTERVENTIONAL
Open Access

Compacting a Single Flow Diverter versus Overlapping Flow Diverters for Intracranial Aneurysms: A Computational Study

R.J. Damiano, V.M. Tutino, N. Paliwal, D. Ma, J.M. Davies, A.H. Siddiqui and H. Meng
American Journal of Neuroradiology March 2017, 38 (3) 603-610; DOI: https://doi.org/10.3174/ajnr.A5062
R.J. Damiano
aFrom the Department of Mechanical and Aerospace Engineering (R.J.D., N.P., D.M., H.M.)
bToshiba Stroke and Vascular Research Center (R.J.D., V.M.T., N.P., D.M., J.M.D., A.H.S., H.M.)
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V.M. Tutino
bToshiba Stroke and Vascular Research Center (R.J.D., V.M.T., N.P., D.M., J.M.D., A.H.S., H.M.)
cDepartment of Biomedical Engineering (V.M.T., H.M.)
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N. Paliwal
aFrom the Department of Mechanical and Aerospace Engineering (R.J.D., N.P., D.M., H.M.)
bToshiba Stroke and Vascular Research Center (R.J.D., V.M.T., N.P., D.M., J.M.D., A.H.S., H.M.)
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D. Ma
aFrom the Department of Mechanical and Aerospace Engineering (R.J.D., N.P., D.M., H.M.)
bToshiba Stroke and Vascular Research Center (R.J.D., V.M.T., N.P., D.M., J.M.D., A.H.S., H.M.)
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J.M. Davies
bToshiba Stroke and Vascular Research Center (R.J.D., V.M.T., N.P., D.M., J.M.D., A.H.S., H.M.)
dDepartment of Neurosurgery (J.M.D., A.H.S., H.M.), University at Buffalo, State University of New York, Buffalo, New York.
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A.H. Siddiqui
bToshiba Stroke and Vascular Research Center (R.J.D., V.M.T., N.P., D.M., J.M.D., A.H.S., H.M.)
dDepartment of Neurosurgery (J.M.D., A.H.S., H.M.), University at Buffalo, State University of New York, Buffalo, New York.
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H. Meng
aFrom the Department of Mechanical and Aerospace Engineering (R.J.D., N.P., D.M., H.M.)
bToshiba Stroke and Vascular Research Center (R.J.D., V.M.T., N.P., D.M., J.M.D., A.H.S., H.M.)
cDepartment of Biomedical Engineering (V.M.T., H.M.)
dDepartment of Neurosurgery (J.M.D., A.H.S., H.M.), University at Buffalo, State University of New York, Buffalo, New York.
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Figures

  • Fig 1.
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    Fig 1.

    FD deployment results in all 3 IAs.

  • Fig 2.
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    Fig 2.

    Porosity and pore density distributions of deployed FDs resulting from all 3 deployment methods in the 3 IAs. A, Deployed FD meshes in the fusiform IA and demarcations of FD zones used for porosity and pore density calculations: proximal vessel (PV), proximal transition (PT), middle (M), distal transition (DT), and distal vessel (DV). These zones are defined on the basis of the compacted FD but applied to all 3 deployment strategies for calculation of porosity and pore density. B, Porosity distribution. C, Pore density distribution. The arrows indicate middle zones in which the compacted FD has lower porosity or higher pore density than the overlapped FDs, whereas the ovals indicate middle zones in which it does not.

  • Fig 3.
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    Fig 3.

    FD mesh compaction achieved in the 3 IAs. A, Compacted meshes at the IA orifice. Orifice areas are highlighted by the circular regions, and the compaction zones, by the rectangular regions. The arrows in the smaller schematics of each IA indicate viewing directions at each IA orifice. The arrows in the larger schematics of each IA orifice indicate the flow direction. Scale bars below each IA orifice indicate distances of 1 mm. B, Plot of compaction coverage (percentage) versus IA orifice area, showing a strong linear relationship.

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    Fig 4.

    Time-averaged, volume-rendered velocity magnitude in all 3 IAs for each FD strategy. Streamlines are plotted to enhance visualization of flow modifications due to each FD strategy. The arrows indicate the flow direction for each untreated IA.

  • Fig 5.
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    Fig 5.

    Changes in time-averaged hemodynamic parameters by FDs in each IA, relative to the untreated IAs. A, Inflow rate at the IA orifice. B, Aneurysm-averaged velocity in the IA sac. C, Aneurysm-averaged wall shear stress on the wall of the IA sac. D, Total absolute circulation at the IA midplane. E, Turnover time in the IA sac. Changes in hemodynamic parameters by FDs are reported as percentages of the values in the untreated IAs. The asterisks indicate instances in which the compacted FD outperformed the overlapped FDs.

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American Journal of Neuroradiology: 38 (3)
American Journal of Neuroradiology
Vol. 38, Issue 3
1 Mar 2017
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Cite this article
R.J. Damiano, V.M. Tutino, N. Paliwal, D. Ma, J.M. Davies, A.H. Siddiqui, H. Meng
Compacting a Single Flow Diverter versus Overlapping Flow Diverters for Intracranial Aneurysms: A Computational Study
American Journal of Neuroradiology Mar 2017, 38 (3) 603-610; DOI: 10.3174/ajnr.A5062

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Compacting a Single Flow Diverter versus Overlapping Flow Diverters for Intracranial Aneurysms: A Computational Study
R.J. Damiano, V.M. Tutino, N. Paliwal, D. Ma, J.M. Davies, A.H. Siddiqui, H. Meng
American Journal of Neuroradiology Mar 2017, 38 (3) 603-610; DOI: 10.3174/ajnr.A5062
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