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Research ArticleINTERVENTIONAL
Open Access

Preliminary Experience with Stent-Assisted Coiling of Aneurysms Arising from Small (<2.5 mm) Cerebral Vessels Using The Low-Profile Visualized Intraluminal Support Device

C.-C. Wang, W. Li, Z.-Z. Feng, B. Hong, Y. Xu, J.-M. Liu and Q.-H. Huang
American Journal of Neuroradiology June 2017, 38 (6) 1163-1168; DOI: https://doi.org/10.3174/ajnr.A5145
C.-C. Wang
aFrom the Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
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W. Li
aFrom the Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
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Z.-Z. Feng
aFrom the Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
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B. Hong
aFrom the Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
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Y. Xu
aFrom the Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
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J.-M. Liu
aFrom the Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
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Q.-H. Huang
aFrom the Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
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    Fig 1.

    (Patient #15) This 46-year-old woman has a history of SAH 6 months ago, with multiple aneurysms (a ruptured anterior communicating artery aneurysm [previously coiled] and bilateral unruptured MCA aneurysms). A, Left ICA DSA showed a tiny saccular aneurysm at left MCA M2 bifurcation (black arrow). B, 3D DSA demonstrated the branch artery arising from the proximal aspect of the aneurysm sac. C, An LVIS stent was deployed in the MCA M2 trunk initially. D, A coil delivery microcatheter was navigated close to the stent interstices, but not through the interstice. Only 1 coil was introduced into the aneurysm sac. E, Initial angiogram after treatment showed the sac residual with patency of the parent vessels. F, The final fluoroscopy demonstrated that the stent was completely opened and totally covered the aneurysm neck. G and H, Follow-up angiography at 10 months demonstrated complete obliteration of the aneurysm with preserved patency of the parent and branch arteries.

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    Fig 2.

    (Patient #16) A, Angiogram showed a ruptured anterior communicating artery aneurysm. B, The aneurysm underwent conventional coiling initially. C and D, Follow-up at 1 month revealed the residual sac filling, and an LVIS stent was then deployed in the ipsilateral anterior cerebral artery. E and F, Total aneurysm occlusion was achieved at 8-month follow-up. In-stent stenosis occurred at the distal stent marker for approximately 55%.

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    Fig 3.

    (Patient #21) A, Oblique left ICA angiogram showed an MCA M1 bifurcation aneurysm. B, Roadmap image revealed the coiling microcatheter and stent placement microcatheter in place (black arrows). C, Native image after stent-assisted coil embolization. D, Seven-month follow-up demonstrated complete occlusion of the aneurysm with the patency of the parent vessel. Insignificant stenosis was found in the inferior branch covered by stent. E and F, The fluoroscopy demonstrated that the stent was fully deployed, with the midsegment expanded across the aneurysm neck and good stent apposition to parent vessel wall.

Tables

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    Table 1:

    Clinical data of all patients

    Patient No.Age (yr), SexRisk FactorsPresentationHHGAneurysm LocationAneurysmPA SizeInitial Angiogram ResultsComplicationsFU Angiogram ResultsFU Time
    SizeNeck
    142, FNSChronic headaches0BT8.58.21.9RAN/ANR13
    257, MHPLt hemiparesis, unconsciousness3MCA8.85.11.8NRN/ACO8
    365, MHPAcute onset of headaches2ACA5.64.61.7NRN/ANR14
    463, MHP, DMLt UE weakness, slurred speech0AComA2.11.42.1CORuptureCO11
    544, FNSIncidental0AComA10.85.22.1CON/ACO8
    661, MHPAcute onset of headaches2MCA4.43.22.0CON/ACO10
    753, MNSIncidental0AComA3.63.12.1NRN/ACO6
    840, MHP, SRecanalized0MCA3.02.92.3NRN/ACO8
    949, MNSHeadaches, seizure1MCA5.04.72.4NRN/ANR6
    1052, MNSIncidental0BT4.43.61.8CON/ACO6
    1161, MHP, DMIncidental0MCA6.56.02.3RAN/ACO9
    1235, MNSChronic headaches0AComA6.73.32.3CON/ACO6
    1351, FHPChronic headaches and dizziness0MCA4.82.71.8RAN/ACO11
    1455, FHP, DLIncidental0MCA3.51.82.2NRN/ACO6
    1546, FHPIncidental0MCA1.81.52.1RAN/ACO10
    1633, MSRecanalized0AComA3.02.32.1NRN/ACO and PA stenosis8
    1754, MHPAcute onset of headaches2MCA3.62.52.0CON/ACO8
    1854, FNSIncidental0MCA3.22.02.3CON/ACO8
    1959, MS, DLIncidental0MCA1.71.51.9RAN/ARA6
    2060, FHPDizziness, nausea, vomiting0MCA7.95.01.9NRN/ACO7
    2149, FNSChronic headaches0MCA3.62.62.3CON/ACO8
    2253, FHPChronic headaches0MCA3.73.22.2RAN/ACO6
    • Note:—ACA indicates anterior cerebral artery; AComA, anterior communicating artery; BT, basilar tip; CO, complete occlusion; DL, dyslipidemia; DM, diabetes mellitus; FU, follow-up; HP, hypertension; Lt, left; N/A, not available; NR, neck residual; NS, not significant; PA, parent artery; RA, residual aneurysm; S, smoking; UE, upper extremity; HHG, Hunt and Hess grade.

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    Table 2:

    Clinical and anatomic results of the stent deployment in small intracranial vessels in previous studies

    Series, yrSample Size (no.)Vessel Diameter (mm)StentTechnical Success Rate (%)Complication (%)Near or Complete Occlution Rate (%)Follow-Up (%)
    ThromboembolicHemorrhagicRecurrence RateIn-Stent Stenosis
    Turk et al, 2007981.5NF1002501000N/A
    Siddiqui et al, 2009881.58EP10012.501002512.5
    Yun and Cho, 20107111.6NF1000010009.1
    Zhang et al, 20106121.8NF, LEO, WP1008.3091.6NAN/A
    Chung et al, 20155311.6EP1009.7096.3011.1
    Kühn et al, 20164441.7NF, EP93.213.62.388.69.16.1
    Aydin et al, 201511802.35LEO Baby97.57.51.396.36.515.6
    Alghamdi et al, 201610432.2LVIS Jr10010595.3517.5
    Puri et al, 2016371.9PED10000N/A028
    • Note:—N/A indicates not available; NF, Neuroform stent; EP, Enterprise stent; WP, Wingspan stent; PED, Pipeline Embolization Device.

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American Journal of Neuroradiology: 38 (6)
American Journal of Neuroradiology
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1 Jun 2017
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C.-C. Wang, W. Li, Z.-Z. Feng, B. Hong, Y. Xu, J.-M. Liu, Q.-H. Huang
Preliminary Experience with Stent-Assisted Coiling of Aneurysms Arising from Small (<2.5 mm) Cerebral Vessels Using The Low-Profile Visualized Intraluminal Support Device
American Journal of Neuroradiology Jun 2017, 38 (6) 1163-1168; DOI: 10.3174/ajnr.A5145

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Preliminary Experience with Stent-Assisted Coiling of Aneurysms Arising from Small (<2.5 mm) Cerebral Vessels Using The Low-Profile Visualized Intraluminal Support Device
C.-C. Wang, W. Li, Z.-Z. Feng, B. Hong, Y. Xu, J.-M. Liu, Q.-H. Huang
American Journal of Neuroradiology Jun 2017, 38 (6) 1163-1168; DOI: 10.3174/ajnr.A5145
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