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Research ArticleInterventional

Intracranial Serpentine Aneurysms: Spontaneous Changes of Angiographic Filling Pattern

S.G. Kandemirli, S. Cekirge, I. Oran, I. Saatci, O. Kizilkilic, C. Cinar, C. Islak and N. Kocer
American Journal of Neuroradiology September 2018, 39 (9) 1662-1668; DOI: https://doi.org/10.3174/ajnr.A5746
S.G. Kandemirli
aFrom the Division of Neuroradiology (S.G.K., O.K., C.I., N.K.), Department of Radiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
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S. Cekirge
bInterventional Neuroradiology Department (S.C.), Koru and Bayındır Hospital, Ankara, Turkey
dInterventional Neuroradiology Department (S.C., I.S.), Yuksek Ihtisas University, Koru Hospital, Ankara, Turkey.
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I. Oran
cDivision of Neuroradiology (I.O., C.C.), Department of Radiology, Ege University Medical Faculty, İzmir, Turkey
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I. Saatci
dInterventional Neuroradiology Department (S.C., I.S.), Yuksek Ihtisas University, Koru Hospital, Ankara, Turkey.
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O. Kizilkilic
aFrom the Division of Neuroradiology (S.G.K., O.K., C.I., N.K.), Department of Radiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
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C. Cinar
cDivision of Neuroradiology (I.O., C.C.), Department of Radiology, Ege University Medical Faculty, İzmir, Turkey
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C. Islak
aFrom the Division of Neuroradiology (S.G.K., O.K., C.I., N.K.), Department of Radiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
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N. Kocer
aFrom the Division of Neuroradiology (S.G.K., O.K., C.I., N.K.), Department of Radiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
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    Fig 1.

    A 37-year-old woman who presented with severe headache. A, Left ICA angiography shows a saccular aneurysm (1.44 × 1.65 cm) at the left MCA bifurcation. B, Repeat angiography 5 years later reveals marked enlargement of the aneurysm (5 × 4 × 4 cm) with incorporation of the upper MCA trunk into the serpentine aneurysm lumen. C and D, Endovascular occlusion of the serpentine aneurysm and the parent artery by coiling and Onyx injection was performed.

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    Fig 2.

    A 32-year-old man who presented with headache and diaphoresis. A, Cerebral angiography shows fusiform enlargement of the right PCA (P2 and P3 segments). B, Six years later, postcontrast MR imaging reveals an enhancing vascular channel on the postgadolinium T1-weighted image surrounded by nonenhancing thrombus. Note the associated mass effect and midline shift. C–E, Cerebral angiography demonstrates marked enlargement of the aneurysm with a tortuous vascular channel.

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    Fig 3.

    A 39-year-old woman who presented with headache. A, Cerebral angiography shows a fusiform aneurysm involving the left MCA M1 and M2 segments. B and C, DSA 1 year later demonstrates marked enlargement of the fusiform aneurysm with sluggish intra-aneurysmal blood flow. D, Six days later, angiography before endovascular treatment reveals partial intra-aneurysmal thrombosis with the classic doughnut shape evident.

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    Fig 4.

    A 39-year-old woman who presented with headache and diplopia. A and B, Initial cerebral angiography shows a giant serpentine aneurysm in the cavernous segment of the right ICA. C and D, Repeat angiogram at the 2-year follow-up demonstrates that the aneurysm has lost its serpentine formation and acquired a fusiform morphology.

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American Journal of Neuroradiology: 39 (9)
American Journal of Neuroradiology
Vol. 39, Issue 9
1 Sep 2018
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Cite this article
S.G. Kandemirli, S. Cekirge, I. Oran, I. Saatci, O. Kizilkilic, C. Cinar, C. Islak, N. Kocer
Intracranial Serpentine Aneurysms: Spontaneous Changes of Angiographic Filling Pattern
American Journal of Neuroradiology Sep 2018, 39 (9) 1662-1668; DOI: 10.3174/ajnr.A5746

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Intracranial Serpentine Aneurysms: Spontaneous Changes of Angiographic Filling Pattern
S.G. Kandemirli, S. Cekirge, I. Oran, I. Saatci, O. Kizilkilic, C. Cinar, C. Islak, N. Kocer
American Journal of Neuroradiology Sep 2018, 39 (9) 1662-1668; DOI: 10.3174/ajnr.A5746
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  • Natural history and clinical outcomes in patients with complex intracranial aneurysms: a review of 115 bypass cases and 22 nonsurgical cases
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  • Giant serpentine aneurysm of the internal cerebral artery and mandibular aneurysm: a case report
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    Chinese Neurosurgical Journal 2019 5 1
  • Giant Serpentine Distal Anterior Cerebral Artery Aneurysm Treated with In Situ Side-to-Side A3-A3 Anastomosis and Aneurysm Resection
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    World Neurosurgery 2020 133
  • A comprehensive analysis and systematic review of giant serpentine aneurysms
    Oday Atallah, Zeinab Hammoud, Bahaa Aljeradat, Yasser F. Almealawy, Amr Badary, Jehad Abd Elqader, Vivek Sanker, Minaam Farooq, Ahmed Muthana, Sura N. Alrubaye, Assma Dwebi, Bipin Chaurasia, Mohammed A. Azab
    Annals of Medicine & Surgery 2025 87 3
  • Ruptured giant serpentine aneurysm of anterior cerebral artery long after Gamma Knife radiosurgery for cerebral arteriovenous malformation
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    Neurochirurgie 2023 69 4

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