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Research ArticleInterventional

Comparison of Prasugrel and Clopidogrel Used as Antiplatelet Medication for Endovascular Treatment of Unruptured Intracranial Aneurysms: A Meta-Analysis

F. Cagnazzo, P. Perrini, P.-H. Lefevre, G. Gascou, C. Dargazanli, C. Riquelme, I. Derraz, D. di Carlo, A. Bonafe and V. Costalat
American Journal of Neuroradiology April 2019, 40 (4) 681-686; DOI: https://doi.org/10.3174/ajnr.A6004
F. Cagnazzo
aFrom the Neuroradiology Department (F.C., P.-H.L., G.G., C.D., C.R., I.D., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France
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P. Perrini
bDepartment of Neurosurgery (P.P., D.d.C.), University of Pisa, Pisa, Italy.
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P.-H. Lefevre
aFrom the Neuroradiology Department (F.C., P.-H.L., G.G., C.D., C.R., I.D., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France
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G. Gascou
aFrom the Neuroradiology Department (F.C., P.-H.L., G.G., C.D., C.R., I.D., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France
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C. Dargazanli
aFrom the Neuroradiology Department (F.C., P.-H.L., G.G., C.D., C.R., I.D., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France
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C. Riquelme
aFrom the Neuroradiology Department (F.C., P.-H.L., G.G., C.D., C.R., I.D., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France
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I. Derraz
aFrom the Neuroradiology Department (F.C., P.-H.L., G.G., C.D., C.R., I.D., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France
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D. di Carlo
bDepartment of Neurosurgery (P.P., D.d.C.), University of Pisa, Pisa, Italy.
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A. Bonafe
aFrom the Neuroradiology Department (F.C., P.-H.L., G.G., C.D., C.R., I.D., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France
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V. Costalat
aFrom the Neuroradiology Department (F.C., P.-H.L., G.G., C.D., C.R., I.D., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France
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REFERENCES

  1. 1.↵
    1. Yamada NK,
    2. Cross DT 3rd.,
    3. Pilgram TK, et al
    . Effect of antiplatelet therapy on thromboembolic complications of elective coil embolization of cerebral aneurysms. AJNR Am J Neuroradiol 2007;28:1778–82 doi:10.3174/ajnr.A0641 pmid:17885244
    Abstract/FREE Full Text
  2. 2.↵
    1. Kang HS,
    2. Han MH,
    3. Kwon BJ, et al
    . Is clopidogrel premedication useful to reduce thromboembolic events during coil embolization for unruptured intracranial aneurysms? Neurosurgery 2010;67:1371–76; discussion 1376 doi:10.1227/NEU.0b013e3181efe3ef pmid:20871459
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Hall R,
    2. Mazer CD
    . Antiplatelet drugs: a review of their pharmacology and management in the perioperative period. Anesth Analg 2011;112:292–318 doi:10.1213/ANE.0b013e318203f38d pmid:21212258
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Wiviott SD
    . Intensity of antiplatelet therapy in patients with acute coronary syndromes and percutaneous coronary intervention: the promise of prasugrel? Cardiol Clin 2008;26:629–37 doi:10.1016/j.ccl.2008.07.003 pmid:18929236
    CrossRefPubMed
  5. 5.↵
    1. Moher D,
    2. Liberati A,
    3. Tetzlaff J, et al
    ; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int J Surg 2010;8:336–41 doi:10.1016/j.ijsu.2010.02.007 pmid:20171303
    CrossRefPubMed
  6. 6.↵
    1. Wells G,
    2. Shea B,
    3. O'Connell D
    . The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonradomized Studies in Meta-Analyses. Ottawa: Ottawa Hospital Research Institute; 2011
  7. 7.↵
    1. Akbari SH,
    2. Reynolds MR,
    3. Kadkhodayan Y, et al
    . Hemorrhagic complications after prasugrel (Effient) therapy for vascular neurointerventional procedures. J Neurointerv Surg 2013;5:337–43 doi:10.1136/neurintsurg-2012-010334 pmid:22555594
    Abstract/FREE Full Text
  8. 8.↵
    1. Cho WS,
    2. Lee J,
    3. Ha EJ, et al
    . Low-dose prasugrel vs clopidogrel-based tailored premedication for endovascular treatment of cerebral aneurysms. Neurosurgery 2018 Aug 20. [Epub ahead of print] doi:10.1093/neuros/nyy341 pmid:30137613
    CrossRefPubMed
  9. 9.↵
    1. Kim CH,
    2. Hwang G,
    3. Kwon OK, et al
    . P2Y12 reaction units threshold for implementing modified antiplatelet preparation in coil embolization of unruptured aneurysms: a prospective validation study. Radiology 2017;282:542–51 doi:10.1148/radiol.2016160542 pmid:27603789
    CrossRefPubMed
  10. 10.↵
    1. Sedat J,
    2. Chau Y,
    3. Gaudart J, et al
    . Prasugrel versus clopidogrel in stent-assisted coil embolization of unruptured intracranial aneurysms. Interv Neuroradiol 2017;23:52–59 doi:10.1177/1591019916669090 pmid:27760885
    CrossRefPubMed
  11. 11.
    1. Lee K,
    2. Park H,
    3. Park I, et al
    . Y-configuration stent-assisted coil embolization for wide-necked intracranial bifurcation aneurysms. J Cerebrovasc Endovasc Neurosurg 2016;18:355–62 doi:10.7461/jcen.2016.18.4.355 pmid:28184345
    CrossRefPubMed
  12. 12.↵
    1. Stetler WR,
    2. Chaudhary N,
    3. Thompson BG, et al
    . Prasugrel is effective and safe for neurointerventional procedures. J Neurointerv Surg 2013;5:332–36 doi:10.1136/neurintsurg-2012-010302 pmid:22619468
    Abstract/FREE Full Text
  13. 13.↵
    1. Lee D,
    2. Song Y,
    3. Han M, et al
    . Low-dose prasugrel in patients with resistance to clopidogrel for the treatment of cerebral aneurysms. Neurointervention 2018;13:124–27 doi:10.5469/neuroint.2018.01088 pmid:30196683
    CrossRefPubMed
  14. 14.↵
    1. Ha EJ,
    2. Cho WS,
    3. Kim JE, et al
    . Prophylactic antiplatelet medication in endovascular treatment of intracranial aneurysms: low-dose prasugrel versus clopidogrel. AJNR Am J Neuroradiol 2016;37:2060–65 doi:10.3174/ajnr.A4864 pmid:27390320
    Abstract/FREE Full Text
  15. 15.↵
    1. Caplain H,
    2. Donat F,
    3. Gaud C, et al
    . Pharmacokinetics of clopidogrel. Semin Thromb Hemost 1999;25(Suppl) 2:25–28 pmid:10440419
    PubMedWeb of Science
  16. 16.↵
    1. Gurbel PA,
    2. Bliden KP,
    3. Samara W, et al
    . Clopidogrel effect on platelet reactivity in patients with stent thrombosis: results of the CREST study. J Am Coll Cardiol 2005;46:1827–32 doi:10.1016/j.jacc.2005.07.056 pmid:16286166
    FREE Full Text
  17. 17.↵
    1. Kim B,
    2. Kim K,
    3. Jeon P, et al
    . Thromboembolic complications in patients with clopidogrel resistance after coil embolization for unruptured intracranial aneurysms. AJNR Am J Neuroradiol 2014;35:1786–92 doi:10.3174/ajnr.A3955 pmid:24831597
    Abstract/FREE Full Text
  18. 18.↵
    1. Choi HH,
    2. Lee JJ,
    3. Cho YD, et al
    . Antiplatelet premedication for stent-assisted coil embolization of intracranial aneurysms: low-dose prasugrel vs clopidogrel. Neurosurgery 2018;83:981–88 doi:10.1093/neuros/nyx591 pmid:29301051
    CrossRefPubMed
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American Journal of Neuroradiology: 40 (4)
American Journal of Neuroradiology
Vol. 40, Issue 4
1 Apr 2019
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Comparison of Prasugrel and Clopidogrel Used as Antiplatelet Medication for Endovascular Treatment of Unruptured Intracranial Aneurysms: A Meta-Analysis
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F. Cagnazzo, P. Perrini, P.-H. Lefevre, G. Gascou, C. Dargazanli, C. Riquelme, I. Derraz, D. di Carlo, A. Bonafe, V. Costalat
Comparison of Prasugrel and Clopidogrel Used as Antiplatelet Medication for Endovascular Treatment of Unruptured Intracranial Aneurysms: A Meta-Analysis
American Journal of Neuroradiology Apr 2019, 40 (4) 681-686; DOI: 10.3174/ajnr.A6004

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Comparison of Prasugrel and Clopidogrel Used as Antiplatelet Medication for Endovascular Treatment of Unruptured Intracranial Aneurysms: A Meta-Analysis
F. Cagnazzo, P. Perrini, P.-H. Lefevre, G. Gascou, C. Dargazanli, C. Riquelme, I. Derraz, D. di Carlo, A. Bonafe, V. Costalat
American Journal of Neuroradiology Apr 2019, 40 (4) 681-686; DOI: 10.3174/ajnr.A6004
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  • Reduction of thromboembolic complications during the endovascular treatment of unruptured aneurysms by employing a tailored dual antiplatelet regimen using aspirin and prasugrel
  • Treatment of distal unruptured intracranial aneurysms using a surface-modified flow diverter under prasugrel monotherapy: a pilot safety trial
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