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Research ArticleInterventional
Open Access

Thrombectomy with Conscious Sedation Compared with General Anesthesia: A DEFUSE 3 Analysis

C.J. Powers, D. Dornbos, M. Mlynash, D. Gulati, M. Torbey, S.M. Nimjee, M.G. Lansberg, G.W. Albers and M.P. Marks
American Journal of Neuroradiology June 2019, 40 (6) 1001-1005; DOI: https://doi.org/10.3174/ajnr.A6059
C.J. Powers
aFrom the Departments of Neurological Surgery (C.J.P., D.D., S.M.N.)
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D. Dornbos III
aFrom the Departments of Neurological Surgery (C.J.P., D.D., S.M.N.)
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M. Mlynash
cDepartments of Neurology and Neurological Science (M.M., M.G.L., G.W.A.)
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D. Gulati
bNeurology (D.G.), Ohio State University Wexner Medical Center, Columbus, Ohio
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M. Torbey
eDepartment of Neurology (M.T.), University of New Mexico, Albuquerque, New Mexico.
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S.M. Nimjee
aFrom the Departments of Neurological Surgery (C.J.P., D.D., S.M.N.)
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M.G. Lansberg
cDepartments of Neurology and Neurological Science (M.M., M.G.L., G.W.A.)
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G.W. Albers
cDepartments of Neurology and Neurological Science (M.M., M.G.L., G.W.A.)
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M.P. Marks
dDiagnostic Radiology (M.P.M.), Stanford University School of Medicine, Stanford, California
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REFERENCES

  1. 1.↵
    1. Brinjikji W,
    2. Pasternak J,
    3. Murad MH, et al
    . Anesthesia-related outcomes for endovascular stroke revascularization: a systematic review and meta-analysis. Stroke 2017;48:2784–91 doi:10.1161/STROKEAHA.117.017786 pmid:28904228
    Abstract/FREE Full Text
  2. 2.↵
    1. Löwhagen Hendén P,
    2. Rentzos A,
    3. Karlsson JE, et al
    . General anesthesia versus conscious sedation for endovascular treatment of acute ischemic stroke: the AnStroke Trial (Anesthesia During Stroke). Stroke 2017;48:1601–07 doi:10.1161/STROKEAHA.117.016554 pmid:28522637
    Abstract/FREE Full Text
  3. 3.↵
    1. Schönenberger S,
    2. Uhlmann L,
    3. Hacke W, et al
    . Effect of conscious sedation vs general anesthesia on early neurological improvement among patients with ischemic stroke undergoing endovascular thrombectomy: a randomized clinical trial. JAMA 2016;316:1986–96 doi:10.1001/jama.2016.16623 pmid:27785516
    CrossRefPubMed
  4. 4.↵
    1. Simonsen CZ,
    2. Yoo AJ,
    3. Sorensen LH, et al
    . Effect of general anesthesia and conscious sedation during endovascular therapy on infarct growth and clinical outcomes in acute ischemic stroke: a randomized clinical trial. JAMA Neurol 2018;75:470–77 doi:10.1001/jamaneurol.2017.4474 pmid:29340574
    CrossRefPubMed
  5. 5.↵
    1. Powers WJ,
    2. Rabinstein AA,
    3. Ackerson T, et al
    ; American Heart Association Stroke Council. 2018 Guidelines for the Early Management of Patients with Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke 2018;49:e46–110 doi:10.1161/STR.0000000000000158 pmid:29367334
    Abstract/FREE Full Text
  6. 6.↵
    1. Albers GW,
    2. Marks MP,
    3. Kemp S, et al
    ; DEFUSE 3 Investigators. Thrombectomy for stroke at 6 to 16 hours with selection by perfusion imaging. N Engl J Med 2018;378:708–18 doi:10.1056/NEJMoa1713973 pmid:29364767
    CrossRefPubMed
  7. 7.↵
    1. Abou-Chebl A,
    2. Yeatts SD,
    3. Yan B, et al
    . Impact of general anesthesia on safety and outcomes in the endovascular arm of Interventional Management of Stroke (IMS) III trial. Stroke 2015;46:2142–48 doi:10.1161/STROKEAHA.115.008761 pmid:26138125
    Abstract/FREE Full Text
  8. 8.↵
    1. Berkhemer OA,
    2. van den Berg LA,
    3. Fransen PS, et al
    ; MR CLEAN investigators. The effect of anesthetic management during intra-arterial therapy for acute stroke in MR CLEAN. Neurology 2016;87:656–64 doi:10.1212/WNL.0000000000002976 pmid:27421546
    CrossRefPubMed
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American Journal of Neuroradiology: 40 (6)
American Journal of Neuroradiology
Vol. 40, Issue 6
1 Jun 2019
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Cite this article
C.J. Powers, D. Dornbos, M. Mlynash, D. Gulati, M. Torbey, S.M. Nimjee, M.G. Lansberg, G.W. Albers, M.P. Marks
Thrombectomy with Conscious Sedation Compared with General Anesthesia: A DEFUSE 3 Analysis
American Journal of Neuroradiology Jun 2019, 40 (6) 1001-1005; DOI: 10.3174/ajnr.A6059

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Thrombectomy with Conscious Sedation Compared with General Anesthesia: A DEFUSE 3 Analysis
C.J. Powers, D. Dornbos, M. Mlynash, D. Gulati, M. Torbey, S.M. Nimjee, M.G. Lansberg, G.W. Albers, M.P. Marks
American Journal of Neuroradiology Jun 2019, 40 (6) 1001-1005; DOI: 10.3174/ajnr.A6059
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