Article Figures & Data
Figures
- Figure.
Distribution of the 90-day mRS score according to white matter disease severity graded with the van Swieten scale score.
Tables
- Table 1:
Baseline characteristics of patients with no-to-minimal (van Sweeten score, 0–2) and moderate-to-severe (van Swieten score, 3–4) white matter disease
van Swieten 0–2 (n = 315) van Swieten 3–4 (n = 74) P Value Age (mean) (±SD) (yr) 66 (±15) 76 (±12) <.001 Male (%) 164 (52) 32 (43) .2 Hypertension (%) 224 (71) 68 (92) <.001 Diabetes (%) 92 (29) 23 (31) .78 Glucose (median) (IQR) 122 (102–146) 131 (115–162) .009 NIHSS (median) (IQR) 15 (10–20) 17 (11–21) .16 ASPECTS (median) (IQR) 8 (7–10) 8 (7–9) .07 Core volume (mean) (±SD) 20 (±24) 19 (±26) .85 Penumbra volume (mean) (±SD) 119 (±71) 124 (±71) .69 Systolic BP on admission (mean) (± SD) 154 (±29) 168 (±29) <.001 Time from last known well to reperfusion (median) (IQR) 274 (180–534) 286 (190–676) .2 Intravenous thrombolysis (%) 160 (51) 29 (39) .09 Prior stroke (%) 52 (16) 19 (26) .09 Note:—BP indicates blood pressure; IQR, interquartile range.
- Table 2:
Outcomes of patients with no-to-minimal (van Swieten score, 0–2) and moderate-to-severe (van Swieten score, 3–4) white matter disease
Outcome van Swieten 0–2 (n = 315) van Swieten 3–4 (n = 74) Unadjusted OR with 95% CI P Value Adjusted OR with 95% CI P Value 90-Day mRS 0–2 (%) 141/295 (45) 13/70 (18) 0.25 (0.13–0.46) <.001 0.37 (0.17–0.75) .008 90-Day mRS 0–3 (%) 184/295 (58) 29/70 (39) 0.43 (0.25–0.73) .002 0.75 (0.40–1.43) .38 Shift in the 90-day mRS NA NA 2.86 (1.83–4.52) <.001 3.05 (1.93–4.84) <.001 Death (%) 47 (15) 19 (26) 1.97 (1.06–3.57) .029 1.14 (0.56–2.26) .71 Symptomatic ICH (%) 13 (4) 4 (5) 1.33 (0.37–3.88) .629 NA NA mTICI ≥ 2b (%) 275 (87) 68 (92) 1.65 (0.72–4.47) .27 NA NA ENI (%) 132 (42) 30 (40) 0.95 (0.56–1.58) .83 NA NA Note:—mTICI indicates modified TICI; ENI, early neurologic improvement; NA, not applicable.
- Table 3:
Outcomes of patients with successful recanalization (mTICI ≥ 2b) according to the severity of baseline white matter disease
Outcome van Swieten 0–2 (n = 275) van Swieten 3–4 (n = 68) P Value 90-Day mRS 0–2 (%) 132/258 (52) 13/65 (20) <.001 90-Day mRS 0–3 (%) 169/258 (65.5) 28/65 (43) .002 Death (%) 34 (12.4) 17 (25.0) .013 Symptomatic ICH (%) 10 (3.6) 3 (4.4) .73 ENI (%) 124 (45.1) 30 (44.1) 1.0 Note:—ENI indicates early neurologic improvement.
Jump to section
Related Articles
Cited By...
- Futile reperfusion of endovascular treatment for acute anterior circulation large vessel occlusion in the ANGEL-ACT registry
- Factors associated with unfavorable outcome after anterior circulation stroke despite successful reperfusion and early neurological improvement
- Impact of leukoaraiosis in patients with acute ischemic stroke treated with thrombectomy: a post hoc analysis of the DIRECT-MT trial
- Influence of renal impairment on clinical outcomes after endovascular recanalization in vertebrobasilar artery occlusions
- Letter by Tang et al regarding the article 'Leukoaraiosis and acute ischemic stroke: 90-day clinical outcome following endovascular recanalization, with proposed "L-ASPECTS"