Carotid Intraplaque Hemorrhage and Stenosis: At What Stage of Plaque Progression Does Intraplaque Hemorrhage Occur, and When is It Most Likely to Be Associated with Symptoms?

A.S. Larson; W. Brinjikji; L. Savastano; A.A. Rabinstein; L. Saba; J. Huston; J.C. Benson

doi:10.3174/ajnr.A7133

Research ArticleExtracranial Vascular

Carotid Intraplaque Hemorrhage and Stenosis: At What Stage of Plaque Progression Does Intraplaque Hemorrhage Occur, and When is It Most Likely to Be Associated with Symptoms?

A.S. Larson, W. Brinjikji, L. Savastano, A.A. Rabinstein, L. Saba, J. Huston and J.C. Benson

American Journal of Neuroradiology July 2021, 42 (7) 1285-1290; DOI: https://doi.org/10.3174/ajnr.A7133

A.S. Larson

aFrom the Departments of Radiology (A.S.L., W.B., J.H., J.C.B.)

bNeurosurgery (A.S.L., W.B., L. Savastano)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for A.S. Larson

W. Brinjikji

aFrom the Departments of Radiology (A.S.L., W.B., J.H., J.C.B.)

bNeurosurgery (A.S.L., W.B., L. Savastano)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for W. Brinjikji

L. Savastano

bNeurosurgery (A.S.L., W.B., L. Savastano)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for L. Savastano

A.A. Rabinstein

cNeurology (A.A.R.), Mayo Clinic, Rochester, Minnesota

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for A.A. Rabinstein

L. Saba

dDepartment of Radiology (L. Saba), University of Cagliari, Cagliari, Italy

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for L. Saba

J. Huston

aFrom the Departments of Radiology (A.S.L., W.B., J.H., J.C.B.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for J. Huston

J.C. Benson

aFrom the Departments of Radiology (A.S.L., W.B., J.H., J.C.B.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for J.C. Benson

Article
Figures & Data
Info & Metrics
Responses
References
PDF

Article Information

vol. 42 no. 7 1285-1290

DOI

https://doi.org/10.3174/ajnr.A7133

PubMed

33888452

Published By

American Journal of Neuroradiology

Print ISSN

0195-6108

Online ISSN

1936-959X

History

Received June 23, 2020
Accepted after revision February 8, 2021
Published online July 13, 2021.

Article Versions

Latest version (April 22, 2021 - 08:48).
You are viewing the most recent version of this article.

Author Information

A.S. Larsona,b,
W. Brinjikjia,b,
L. Savastanob,
A.A. Rabinsteinc,
L. Sabad,
J. Hustona and
J.C. Bensona

^aFrom the Departments of Radiology (A.S.L., W.B., J.H., J.C.B.)
^bNeurosurgery (A.S.L., W.B., L. Savastano)
^cNeurology (A.A.R.), Mayo Clinic, Rochester, Minnesota
^dDepartment of Radiology (L. Saba), University of Cagliari, Cagliari, Italy

Please address correspondence to Anthony Larson, BS, Mayo Clinic Department of Radiology, 200 First St SW, Rochester, MN 55905; e-mail: lars4689{at}umn.edu; @TonyLarsonBS; @WBrinjikji; @SavastanoPh

View Full Text

Altmetrics

Cited By...

17 Citations
Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

MR Imaging of Carotid Artery Atherosclerosis: Updated Evidence on High-Risk Plaque Features and Emerging Trends

J.C. Benson, L. Saba, G. Bathla, W. Brinjikji, V. Nardi, G. Lanzino

American Journal of Neuroradiology 2023 44 8
Temporal Trends and Determinants of Stroke Risk in Patients With Medically Treated Asymptomatic Carotid Stenosis

Michiel H.F. Poorthuis, Yoel Solomon, Reinier A.R. Herings, Frank L.J. Visseren, L. Jaap Kappelle, Michiel L. Bots, Ina Rissanen, Gert J. de Borst

Stroke 2023 54 7
Integrated head and neck imaging of symptomatic patients with stroke using simultaneous non-contrast cardiovascular magnetic resonance angiography and intraplaque hemorrhage imaging as compared with digital subtraction angiography

Yuxi Jia, Xiaoming Liu, Lan Zhang, Xiangchuang Kong, Shuo Chen, Lei Zhang, Jiazheng Wang, Shenglei Shu, Jia Liu, Xiaona Fu, Dingxi Liu, Jing Wang, Heshui Shi

Journal of Cardiovascular Magnetic Resonance 2022 24 1
The application of the nnU-Net-based automatic segmentation model in assisting carotid artery stenosis and carotid atherosclerotic plaque evaluation

Ying Zhu, Liwei Chen, Wenjie Lu, Yongjun Gong, Ximing Wang

Frontiers in Physiology 2022 13
Nonstenotic Carotid Plaques and Embolic Stroke of Undetermined Source: A Multimodality Review

A.S. Larson, W. Brinjikji, A. Lekah, J.P. Klaas, G. Lanzino, J. Huston, L. Saba, J.C. Benson

American Journal of Neuroradiology 2023 44 2
A clinical-radiomics combined model based on carotid atherosclerotic plaque for prediction of ischemic stroke

Na Han, Wanjun Hu, Yurong Ma, Yu Zheng, Songhong Yue, Laiyang Ma, Jie Li, Jing Zhang

Frontiers in Neurology 2024 15
In vitro analysis of carotid lesions using a preliminary microwave sensor to detect vulnerable plaques: Correlation with histology, Duplex ultrasound examination, and computed tomography scanner: The Imaging and Microwave Phenotyping Assessment of Carotid stenosis Threat (IMPACT) study

Rania Shahbaz, Etienne Charpentier, Maharajah Ponnaiah, Frédérique Deshours, Hamid Kokabi, Isabelle Brochériou, Gilles Le Naour, Alban Redheuil, Fabien Koskas, Jean-Michel Davaine

JVS-Vascular Science 2024 5
Unfinished debate: Why IPH-based metrics are still needed—An Editorial for “Signal intensity and volume of carotid intraplaque hemorrhage on magnetic resonance imaging and the risk of ipsilateral cerebrovascular events: the Plaque At RISK (PARISK) study”

Chun Yuan, Gador Canton, Thomas S. Hatsukami

Journal of Cardiovascular Magnetic Resonance 2024 26 2
Another Step toward the Understanding of Carotid Artery Pathology

A. Podlasek, R.J. Simpson

American Journal of Neuroradiology 2021 42 7
Benefits of prophylactic carotid revascularization in patients with asymptomatic carotid artery stenosis undergoing coronary artery bypass surgery: A narrative review

Mateja Kaja Jezovnik, Pavel Poredos, Peter Poredos

Vascular Medicine 2025 30 1
Carotid and aortic plaque imaging using 3D gradient-echo imaging and the three-point Dixon method with improved motion-sensitized driven-equilibrium (iMSDE)

Norikazu Koori, Hiroki Kamekawa, Takehiro Naito, Yasuo Takatsu, Hiraku Fuse, Shin Miyakawa, Kenji Yasue, Masato Takahashi, Kazuma Kurata

Magnetic Resonance Imaging 2024 111
Diagnostic accuracy of carotid plaque magnetic resonance imaging compared to histopathology in symptomatic carotid artery stenosis

Akash Jayanandaiah, Anoop Ayyappan, Naveen K. Paramasivan, Deepthi Narasimhaiah, Sapna E. Sreedharan, Jissa V. Thulaseedharan, P.N. Sylaja

Journal of Clinical Neuroscience 2024 128
High Wall Shear Stress Is Related to Complicated American Heart Association Lesion Type VI Plaques in Mild-to-Moderate ICA Stenosis: A 3D Cardiovascular MRI Study

Christoph Strecker, Axel Joachim Krafft, Tobias Saam, Markus Huellebrand, Ute Ludwig, Anja Hennemuth, Jürgen Hennig, Andreas Harloff

American Journal of Neuroradiology 2025 46 5
Intraplaque Hemorrhage: A Comparative Study of Vulnerable Plaque With Magnetic Resonance Imaging and Doppler Ultrasonography

Mine Sezgin, Sevil Yusifli, Mehmet Barburoğlu, Esme Ekizoğlu, Nilüfer Yeşilot

Journal of Clinical Ultrasound 2025
Intraplaque hemorrhage on magnetic resonance angiography: How often do signal abnormalities persist on follow-up imaging?

John C. Benson, Adnan Shahid, Anthony S. Larson, Waleed Brinjikji, Deena Nasr, Luca Saba, Giuseppe Lanzino, Luis E. Savastano

Clinical Neurology and Neurosurgery 2023 229
Intraplaque hemorrhage volume in patients with carotid atherosclerosis: How informative is it?

Sujin Kim, Somin Jeong, Hyo Sung Kwak, Dac Hong An Ngo

Journal of Stroke and Cerebrovascular Diseases 2024 33 12
Significance of myeloperoxidase, pentraxin-3 and soluble urokinase plasminogen activator receptor determination in patients with moderate carotid artery stenosis

Ana Ruzanovic, Marija Saric-Matutinovic, Neda Milinkovic, Snezana Jovicic, Andreja Dimic, David Matejevic, Ognjen Kostic, Igor Koncar, Svetlana Ignjatovic

Scandinavian Journal of Clinical and Laboratory Investigation 2024 84 7-8

PreviousNext

In this issue

American Journal of Neuroradiology

Vol. 42, Issue 7

1 Jul 2021

Table of Contents
Index by author
Complete Issue (PDF)

Download PDF

Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Carotid Intraplaque Hemorrhage and Stenosis: At What Stage of Plaque Progression Does Intraplaque Hemorrhage Occur, and When is It Most Likely to Be Associated with Symptoms?

Message Subject (Your Name) has sent you a message from American Journal of Neuroradiology

Message Body (Your Name) thought you would like to see the American Journal of Neuroradiology web site.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Cite this article

A.S. Larson, W. Brinjikji, L. Savastano, A.A. Rabinstein, L. Saba, J. Huston, J.C. Benson

Carotid Intraplaque Hemorrhage and Stenosis: At What Stage of Plaque Progression Does Intraplaque Hemorrhage Occur, and When is It Most Likely to Be Associated with Symptoms?

American Journal of Neuroradiology Jul 2021, 42 (7) 1285-1290; DOI: 10.3174/ajnr.A7133

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

0 Responses

Respond to this article

Bookmark this article

User Name *

Password *

Remember my user name & password.

Carotid Intraplaque Hemorrhage and Stenosis: At What Stage of Plaque Progression Does Intraplaque Hemorrhage Occur, and When is It Most Likely to Be Associated with Symptoms?

A.S. Larson, W. Brinjikji, L. Savastano, A.A. Rabinstein, L. Saba, J. Huston, J.C. Benson

American Journal of Neuroradiology Jul 2021, 42 (7) 1285-1290; DOI: 10.3174/ajnr.A7133

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Purchase

Jump to section

Article
Figures & Data
Info & Metrics
Responses
References
PDF

No related articles found.

PubMed
Google Scholar

Cited By...

High Wall Shear Stress Is Related to Complicated American Heart Association Lesion Type VI Plaques in Mild-to-Moderate ICA Stenosis: A 3D Cardiovascular MRI Study
MR Imaging of Carotid Artery Atherosclerosis: Updated Evidence on High-Risk Plaque Features and Emerging Trends
Nonstenotic Carotid Plaques and Embolic Stroke of Undetermined Source: A Multimodality Review
Another Step toward the Understanding of * Carotid Artery Pathology

Crossref (17)
Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

MR Imaging of Carotid Artery Atherosclerosis: Updated Evidence on High-Risk Plaque Features and Emerging Trends

J.C. Benson, L. Saba, G. Bathla, W. Brinjikji, V. Nardi, G. Lanzino

American Journal of Neuroradiology 2023 44 8
Temporal Trends and Determinants of Stroke Risk in Patients With Medically Treated Asymptomatic Carotid Stenosis

Michiel H.F. Poorthuis, Yoel Solomon, Reinier A.R. Herings, Frank L.J. Visseren, L. Jaap Kappelle, Michiel L. Bots, Ina Rissanen, Gert J. de Borst

Stroke 2023 54 7
Integrated head and neck imaging of symptomatic patients with stroke using simultaneous non-contrast cardiovascular magnetic resonance angiography and intraplaque hemorrhage imaging as compared with digital subtraction angiography

Yuxi Jia, Xiaoming Liu, Lan Zhang, Xiangchuang Kong, Shuo Chen, Lei Zhang, Jiazheng Wang, Shenglei Shu, Jia Liu, Xiaona Fu, Dingxi Liu, Jing Wang, Heshui Shi

Journal of Cardiovascular Magnetic Resonance 2022 24 1
The application of the nnU-Net-based automatic segmentation model in assisting carotid artery stenosis and carotid atherosclerotic plaque evaluation

Ying Zhu, Liwei Chen, Wenjie Lu, Yongjun Gong, Ximing Wang

Frontiers in Physiology 2022 13
Nonstenotic Carotid Plaques and Embolic Stroke of Undetermined Source: A Multimodality Review

A.S. Larson, W. Brinjikji, A. Lekah, J.P. Klaas, G. Lanzino, J. Huston, L. Saba, J.C. Benson

American Journal of Neuroradiology 2023 44 2
A clinical-radiomics combined model based on carotid atherosclerotic plaque for prediction of ischemic stroke

Na Han, Wanjun Hu, Yurong Ma, Yu Zheng, Songhong Yue, Laiyang Ma, Jie Li, Jing Zhang

Frontiers in Neurology 2024 15
In vitro analysis of carotid lesions using a preliminary microwave sensor to detect vulnerable plaques: Correlation with histology, Duplex ultrasound examination, and computed tomography scanner: The Imaging and Microwave Phenotyping Assessment of Carotid stenosis Threat (IMPACT) study

Rania Shahbaz, Etienne Charpentier, Maharajah Ponnaiah, Frédérique Deshours, Hamid Kokabi, Isabelle Brochériou, Gilles Le Naour, Alban Redheuil, Fabien Koskas, Jean-Michel Davaine

JVS-Vascular Science 2024 5
Unfinished debate: Why IPH-based metrics are still needed—An Editorial for “Signal intensity and volume of carotid intraplaque hemorrhage on magnetic resonance imaging and the risk of ipsilateral cerebrovascular events: the Plaque At RISK (PARISK) study”

Chun Yuan, Gador Canton, Thomas S. Hatsukami

Journal of Cardiovascular Magnetic Resonance 2024 26 2
Another Step toward the Understanding of Carotid Artery Pathology

A. Podlasek, R.J. Simpson

American Journal of Neuroradiology 2021 42 7
Benefits of prophylactic carotid revascularization in patients with asymptomatic carotid artery stenosis undergoing coronary artery bypass surgery: A narrative review

Mateja Kaja Jezovnik, Pavel Poredos, Peter Poredos

Vascular Medicine 2025 30 1

Main menu

User menu

Search

American Journal of Neuroradiology

Carotid Intraplaque Hemorrhage and Stenosis: At What Stage of Plaque Progression Does Intraplaque Hemorrhage Occur, and When is It Most Likely to Be Associated with Symptoms?

Article Information

Article Versions

Author Information

Altmetrics

Cited By...

In this issue

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Indexed Content

Cases

Special Collections

More from AJNR

Multimedia

Resources

About Us

American Society of Neuroradiology