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Research ArticleSpine Imaging and Spine Image-Guided Interventions

Diagnostic Performance of Decubitus Photon-Counting Detector CT Myelography for the Detection of CSF-Venous Fistulas

Ajay A. Madhavan, Jeremy K. Cutsforth-Gregory, Waleed Brinjikji, Girish Bathla, John C. Benson, Felix E. Diehn, Laurence J. Eckel, Ian T. Mark, Pearse P. Morris, Melissa A. Payne, Jared T. Verdoorn, Nikkole M. Weber, Lifeng Yu, Francis Baffour, Joel G. Fletcher and Cynthia H. McCollough
American Journal of Neuroradiology December 2023, 44 (12) 1445-1450; DOI: https://doi.org/10.3174/ajnr.A8040
Ajay A. Madhavan
aFrom the Department of Radiology (A.A.M., W.B., G.B., J.C.B., F.E.D., L.J.E., I.T.M., P.P.M., J.T.V., N.M.W., L.Y., F.B., J.G.F., C.H.M.), Mayo Clinic, Rochester, Minnesota
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Jeremy K. Cutsforth-Gregory
bDepartment of Neurology (J.K.C.-G., M.A.P.), Mayo Clinic, Rochester, Minnesota
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  • ORCID record for Jeremy K. Cutsforth-Gregory
Waleed Brinjikji
aFrom the Department of Radiology (A.A.M., W.B., G.B., J.C.B., F.E.D., L.J.E., I.T.M., P.P.M., J.T.V., N.M.W., L.Y., F.B., J.G.F., C.H.M.), Mayo Clinic, Rochester, Minnesota
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  • ORCID record for Waleed Brinjikji
Girish Bathla
aFrom the Department of Radiology (A.A.M., W.B., G.B., J.C.B., F.E.D., L.J.E., I.T.M., P.P.M., J.T.V., N.M.W., L.Y., F.B., J.G.F., C.H.M.), Mayo Clinic, Rochester, Minnesota
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  • ORCID record for Girish Bathla
John C. Benson
aFrom the Department of Radiology (A.A.M., W.B., G.B., J.C.B., F.E.D., L.J.E., I.T.M., P.P.M., J.T.V., N.M.W., L.Y., F.B., J.G.F., C.H.M.), Mayo Clinic, Rochester, Minnesota
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  • ORCID record for John C. Benson
Felix E. Diehn
aFrom the Department of Radiology (A.A.M., W.B., G.B., J.C.B., F.E.D., L.J.E., I.T.M., P.P.M., J.T.V., N.M.W., L.Y., F.B., J.G.F., C.H.M.), Mayo Clinic, Rochester, Minnesota
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Laurence J. Eckel
aFrom the Department of Radiology (A.A.M., W.B., G.B., J.C.B., F.E.D., L.J.E., I.T.M., P.P.M., J.T.V., N.M.W., L.Y., F.B., J.G.F., C.H.M.), Mayo Clinic, Rochester, Minnesota
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Ian T. Mark
aFrom the Department of Radiology (A.A.M., W.B., G.B., J.C.B., F.E.D., L.J.E., I.T.M., P.P.M., J.T.V., N.M.W., L.Y., F.B., J.G.F., C.H.M.), Mayo Clinic, Rochester, Minnesota
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Pearse P. Morris
aFrom the Department of Radiology (A.A.M., W.B., G.B., J.C.B., F.E.D., L.J.E., I.T.M., P.P.M., J.T.V., N.M.W., L.Y., F.B., J.G.F., C.H.M.), Mayo Clinic, Rochester, Minnesota
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Melissa A. Payne
bDepartment of Neurology (J.K.C.-G., M.A.P.), Mayo Clinic, Rochester, Minnesota
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Jared T. Verdoorn
aFrom the Department of Radiology (A.A.M., W.B., G.B., J.C.B., F.E.D., L.J.E., I.T.M., P.P.M., J.T.V., N.M.W., L.Y., F.B., J.G.F., C.H.M.), Mayo Clinic, Rochester, Minnesota
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Nikkole M. Weber
aFrom the Department of Radiology (A.A.M., W.B., G.B., J.C.B., F.E.D., L.J.E., I.T.M., P.P.M., J.T.V., N.M.W., L.Y., F.B., J.G.F., C.H.M.), Mayo Clinic, Rochester, Minnesota
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Lifeng Yu
aFrom the Department of Radiology (A.A.M., W.B., G.B., J.C.B., F.E.D., L.J.E., I.T.M., P.P.M., J.T.V., N.M.W., L.Y., F.B., J.G.F., C.H.M.), Mayo Clinic, Rochester, Minnesota
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Francis Baffour
aFrom the Department of Radiology (A.A.M., W.B., G.B., J.C.B., F.E.D., L.J.E., I.T.M., P.P.M., J.T.V., N.M.W., L.Y., F.B., J.G.F., C.H.M.), Mayo Clinic, Rochester, Minnesota
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Joel G. Fletcher
aFrom the Department of Radiology (A.A.M., W.B., G.B., J.C.B., F.E.D., L.J.E., I.T.M., P.P.M., J.T.V., N.M.W., L.Y., F.B., J.G.F., C.H.M.), Mayo Clinic, Rochester, Minnesota
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Cynthia H. McCollough
aFrom the Department of Radiology (A.A.M., W.B., G.B., J.C.B., F.E.D., L.J.E., I.T.M., P.P.M., J.T.V., N.M.W., L.Y., F.B., J.G.F., C.H.M.), Mayo Clinic, Rochester, Minnesota
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    FIG 1.

    Definitive CVF on PC-CTM involving both the IVVP and EVVP in a patient meeting the ICHD-3 criteria for SIH. Axial MIP images derived from 0.4-mm 40-keV slices demonstrate a left T6 CVF involving the paraspinal segmental vein (A and B, solid arrows) and extending into the hemiazygos system (B, dashed arrows). Sagittal and coronal 40-keV images (C and D) obtained at a different time point show additional involvement of the IVVP, with contrast extending down to the level of T7 (C and D, arrows).

  • FIG 2.
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    FIG 2.

    Definitive left T10 CVF involving the ventral IVVP and basivertebral vein in a patient with previously negative findings on decubitus dynamic EID CTM. Axial 40-keV 0.4-mm (A) and T3D 0.2-mm (B) images from PC-CTM, both at the same window/level setting, demonstrate contrast opacification of the T10 basivertebral vein (A and B, arrows), which is most conspicuous on the 40-keV image but defined with better resolution on the T3D image. Axial 40-keV 0.4-mm (C) and T3D 0.2-mm (D) images at the same window/level setting from an adjacent slice at an earlier time point show additional involvement of the ventral IVVP (C and D, arrows). This subtle finding is best seen on the 40-keV image. Neither finding was seen on retrospective review of the patient's dynamic EID CTM (E and F).

  • FIG 3.
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    FIG 3.

    Definitive CVFs involving the IVVP in 2 separate patients, illustrating the complementary benefits of high-spatial-resolution and low kiloelectron volt VMIs. Both patients had a Bern score of 1. The first patient had no prior decubitus myelographic studies, while the second patient initially underwent negative decubitus DSM and negative decubitus EID CTM (not shown). In the first patient (A and B), an axial 0.2-mm T3D image (A) from PC-CTM demonstrates a left T6 CVF involving the IVVP (A, solid arrow). The draining vein is clearly separate from the thecal sac (A, dashed arrow), distinguishing it from a direct epidural leak. Concurrent axial 40-keV VMI reconstructed at the minimum allowed slice thickness of 0.4 mm with identical window/level settings demonstrates higher attenuation of the same finding (B, arrow), but the lower spatial resolution less clearly distinguishes the vein from the thecal sac (B, dashed arrow). In the second patient (C and D), axial (C) and coronal (D) 40-keV 0.4-mm VMIs from PC-CTM demonstrate a left T10 CVF of the IVVP (C and D, arrows). In this case, the 0.4-mm slice thickness was sufficient to distinguish the vein from the thecal sac. In both patients, the venous contrast washed away on subsequently obtained images (not shown).

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American Journal of Neuroradiology: 44 (12)
American Journal of Neuroradiology
Vol. 44, Issue 12
1 Dec 2023
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Ajay A. Madhavan, Jeremy K. Cutsforth-Gregory, Waleed Brinjikji, Girish Bathla, John C. Benson, Felix E. Diehn, Laurence J. Eckel, Ian T. Mark, Pearse P. Morris, Melissa A. Payne, Jared T. Verdoorn, Nikkole M. Weber, Lifeng Yu, Francis Baffour, Joel G. Fletcher, Cynthia H. McCollough
Diagnostic Performance of Decubitus Photon-Counting Detector CT Myelography for the Detection of CSF-Venous Fistulas
American Journal of Neuroradiology Dec 2023, 44 (12) 1445-1450; DOI: 10.3174/ajnr.A8040

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Photon-Count CT Myelography of CSF-Venous Fistulas
Ajay A. Madhavan, Jeremy K. Cutsforth-Gregory, Waleed Brinjikji, Girish Bathla, John C. Benson, Felix E. Diehn, Laurence J. Eckel, Ian T. Mark, Pearse P. Morris, Melissa A. Payne, Jared T. Verdoorn, Nikkole M. Weber, Lifeng Yu, Francis Baffour, Joel G. Fletcher, Cynthia H. McCollough
American Journal of Neuroradiology Dec 2023, 44 (12) 1445-1450; DOI: 10.3174/ajnr.A8040
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