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Research ArticleFunctional

Connectomic Basis for Tremor Control in Stereotactic Radiosurgical Thalamotomy

E.H. Middlebrooks, R.A. Popple, E. Greco, L. Okromelidze, H.C. Walker, D.A. Lakhani, A.R. Anderson, E.M. Thomas, H.D. Deshpande, B.A. McCullough, N.P. Stover, V.W. Sung, A.P. Nicholas, D.G. Standaert, T. Yacoubian, M.N. Dean, J.A. Roper, S.S. Grewal, M.T. Holland, J.N. Bentley, B.L. Guthrie and M. Bredel
American Journal of Neuroradiology February 2023, 44 (2) 157-164; DOI: https://doi.org/10.3174/ajnr.A7778
E.H. Middlebrooks
aFrom the Departments of Radiology (E.H.M., E.G., L.O., D.A.L.)
bNeurosurgery (E.H.M., S.S.G.), Mayo Clinic, Jacksonville, Florida
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R.A. Popple
cDepartments of Radiation Oncology (R.A.P., A.R.A., E.M.T., M.B.)
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E. Greco
aFrom the Departments of Radiology (E.H.M., E.G., L.O., D.A.L.)
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L. Okromelidze
aFrom the Departments of Radiology (E.H.M., E.G., L.O., D.A.L.)
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  • ORCID record for L. Okromelidze
H.C. Walker
dNeurology (H.C.W., B.A.M., N.P.S., V.W.S., A.P.N., D.G.S., T.Y., M.N.D.)
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D.A. Lakhani
aFrom the Departments of Radiology (E.H.M., E.G., L.O., D.A.L.)
gDepartment of Radiology (D.A.L.), West Virginia University, Morgantown, West Virginia
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A.R. Anderson
cDepartments of Radiation Oncology (R.A.P., A.R.A., E.M.T., M.B.)
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E.M. Thomas
cDepartments of Radiation Oncology (R.A.P., A.R.A., E.M.T., M.B.)
hDepartment of Radiation Oncology (E.M.T.), Ohio State University, Columbus, Ohio
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H.D. Deshpande
eRadiology (H.D.D.)
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B.A. McCullough
dNeurology (H.C.W., B.A.M., N.P.S., V.W.S., A.P.N., D.G.S., T.Y., M.N.D.)
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N.P. Stover
dNeurology (H.C.W., B.A.M., N.P.S., V.W.S., A.P.N., D.G.S., T.Y., M.N.D.)
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V.W. Sung
dNeurology (H.C.W., B.A.M., N.P.S., V.W.S., A.P.N., D.G.S., T.Y., M.N.D.)
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A.P. Nicholas
dNeurology (H.C.W., B.A.M., N.P.S., V.W.S., A.P.N., D.G.S., T.Y., M.N.D.)
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D.G. Standaert
dNeurology (H.C.W., B.A.M., N.P.S., V.W.S., A.P.N., D.G.S., T.Y., M.N.D.)
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T. Yacoubian
dNeurology (H.C.W., B.A.M., N.P.S., V.W.S., A.P.N., D.G.S., T.Y., M.N.D.)
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M.N. Dean
dNeurology (H.C.W., B.A.M., N.P.S., V.W.S., A.P.N., D.G.S., T.Y., M.N.D.)
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J.A. Roper
iSchool of Kinesiology (J.A.R.), Auburn University, Auburn, Alabama
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S.S. Grewal
bNeurosurgery (E.H.M., S.S.G.), Mayo Clinic, Jacksonville, Florida
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M.T. Holland
fNeurosurgery (M.T.H., J.N.B., B.L.G.), University of Alabama at Birmingham, Birmingham, Alabama
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J.N. Bentley
fNeurosurgery (M.T.H., J.N.B., B.L.G.), University of Alabama at Birmingham, Birmingham, Alabama
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B.L. Guthrie
fNeurosurgery (M.T.H., J.N.B., B.L.G.), University of Alabama at Birmingham, Birmingham, Alabama
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M. Bredel
cDepartments of Radiation Oncology (R.A.P., A.R.A., E.M.T., M.B.)
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References

  1. 1.↵
    1. Louis ED,
    2. Ferreira JJ
    . How common is the most common adult movement disorder? Update on the worldwide prevalence of essential tremor. Mov Disord 2010;25:534–41 doi:10.1002/mds.22838 pmid:20175185
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Sporns O,
    2. Tononi G,
    3. Kötter R
    . The human connectome: a structural description of the human brain. PLoS Comput Biol 2005;1:e42 doi:10.1371/journal.pcbi.0010042 pmid:16201007
    CrossRefPubMed
  3. 3.↵
    1. Lozano AM,
    2. Lipsman N
    . Probing and regulating dysfunctional circuits using deep brain stimulation. Neuron 2013;77:406–24 doi:10.1016/j.neuron.2013.01.020 pmid:23395370
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Henderson JM
    . “Connectomic surgery”: diffusion tensor imaging (DTI) tractography as a targeting modality for surgical modulation of neural networks. Front Integr Neurosci 2012;6:15 doi:10.3389/fnint.2012.00015 pmid:22536176
    CrossRefPubMed
  5. 5.↵
    1. Middlebrooks EH,
    2. Domingo RA,
    3. Vivas-Buitrago T, et al
    . Neuroimaging advances in deep brain stimulation: review of indications, anatomy, and brain connectomics. AJNR Am J Neuroradiol 2020;41:1558–68 doi:10.3174/ajnr.A6693 pmid:32816768
    Abstract/FREE Full Text
  6. 6.↵
    1. Middlebrooks EH,
    2. Okromelidze L,
    3. Carter RE, et al
    . Directed stimulation of the dentato-rubro-thalamic tract for deep brain stimulation in essential tremor: a blinded clinical trial. Neuroradiol J 2022;35:203–12 doi:10.1177/19714009211036689 pmid:34340623
    CrossRefPubMed
  7. 7.↵
    1. Middlebrooks EH,
    2. Okromelidze L,
    3. Wong JK, et al
    . Connectivity correlates to predict essential tremor deep brain stimulation outcome: evidence for a common treatment pathway. Neuroimage Clin 2021;32:102846 doi:10.1016/j.nicl.2021.102846 pmid:34624639
    CrossRefPubMed
  8. 8.↵
    1. Middlebrooks EH,
    2. Tuna IS,
    3. Almeida L, et al
    . Structural connectivity-based segmentation of the thalamus and prediction of tremor improvement following thalamic deep brain stimulation of the ventral intermediate nucleus. Neuroimage Clin 2018;20:1266–73 doi:10.1016/j.nicl.2018.10.009 pmid:30318403
    CrossRefPubMed
  9. 9.↵
    1. Neudorfer C,
    2. Kroneberg D,
    3. Al-Fatly B, et al
    . Personalizing deep brain stimulation using advanced imaging sequences. Ann Neurol 2022;91:613–28 doi:10.1002/ana.26326 pmid:35165921
    CrossRefPubMed
  10. 10.↵
    1. Tsuboi T,
    2. Wong JK,
    3. Eisinger RS, et al
    . Comparative connectivity correlates of dystonic and essential tremor deep brain stimulation. Brain 2021;144:1774–86 doi:10.1093/brain/awab074 pmid:33889943
    CrossRefPubMed
  11. 11.↵
    1. Wong JK,
    2. Hess CW,
    3. Almeida L, et al
    . Deep brain stimulation in essential tremor: targets, technology, and a comprehensive review of clinical outcomes. Expert Rev Neurother 2020;20:319–31 doi:10.1080/14737175.2020.1737017 pmid:32116065
    CrossRefPubMed
  12. 12.↵
    1. Wong JK,
    2. Middlebrooks EH,
    3. Grewal SS, et al
    . A comprehensive review of brain connectomics and imaging to improve deep brain stimulation outcomes. Mov Disord 2020;35:741–51 doi:10.1002/mds.28045 pmid:32281147
    CrossRefPubMed
  13. 13.↵
    1. Wong JK,
    2. Patel B,
    3. Middlebrooks EH, et al
    . Connectomic analysis of unilateral dual-lead thalamic deep brain stimulation for treatment of multiple sclerosis tremor. Brain Commun 2022;4:fcac063 doi:10.1093/braincomms/fcac063 pmid:35368612
    CrossRefPubMed
  14. 14.↵
    1. Al-Fatly B,
    2. Ewert S,
    3. Kubler D, et al
    . Connectivity profile of thalamic deep brain stimulation to effectively treat essential tremor. Brain 2019;142:3086–98 doi:10.1093/brain/awz236 pmid:31377766
    CrossRefPubMed
  15. 15.↵
    1. Middlebrooks EH,
    2. Grewal SS,
    3. Stead M, et al
    . Differences in functional connectivity profiles as a predictor of response to anterior thalamic nucleus deep brain stimulation for epilepsy: a hypothesis for the mechanism of action and a potential biomarker for outcomes. Neurosurg Focus 2018;45:E7 doi:10.3171/2018.5.FOCUS18151 pmid:30064322
    CrossRefPubMed
  16. 16.↵
    1. Middlebrooks EH,
    2. He X,
    3. Grewal SS, et al
    . Neuroimaging and thalamic connectomics in epilepsy neuromodulation. Epilepsy Res 2022;182:106916 doi:10.1016/j.eplepsyres.2022.106916 pmid:35367691
    CrossRefPubMed
  17. 17.↵
    1. Middlebrooks EH,
    2. Jain A,
    3. Okromelidze L, et al
    . Acute brain activation patterns of high- versus low-frequency stimulation of the anterior nucleus of the thalamus during deep brain stimulation for epilepsy. Neurosurgery 2021;89:901–08 doi:10.1093/neuros/nyab306 pmid:34460925
    CrossRefPubMed
  18. 18.↵
    1. Middlebrooks EH,
    2. Lin C,
    3. Okromelidze L, et al
    . Functional activation patterns of deep brain stimulation of the anterior nucleus of the thalamus. World Neurosurg 2020;136:357–63.e2 doi:10.1016/j.wneu.2020.01.108 pmid:32001414
    CrossRefPubMed
  19. 19.↵
    1. Tsuboi T,
    2. Charbel M,
    3. Peterside DT, et al
    . Pallidal connectivity profiling of stimulation-induced dyskinesia in Parkinson’s disease. Mov Disord 2021;36:380–88 doi:10.1016/j.wneu.2020.01.108 pmid:33002233
    CrossRefPubMed
  20. 20.↵
    1. Horn A,
    2. Reich M,
    3. Vorwerk J, et al
    . Connectivity predicts deep brain stimulation outcome in Parkinson disease. Ann Neurol 2017;82:67–78 doi:10.1002/ana.24974 pmid:28586141
    CrossRefPubMed
  21. 21.↵
    1. Li N,
    2. Baldermann JC,
    3. Kibleur A, et al
    . A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder. Nat Commun 2020;11:3364 doi:10.1038/s41467-020-16734-3 pmid:32620886
    CrossRefPubMed
  22. 22.↵
    1. Reich MM,
    2. Horn A,
    3. Lange F, et al
    . Probabilistic mapping of the antidystonic effect of pallidal neurostimulation: a multicentre imaging study. Brain 2019;142:1386–98 doi:10.1093/brain/awz046 pmid:30851091
    CrossRefPubMed
  23. 23.↵
    1. Kundu P,
    2. Inati SJ,
    3. Evans JW, et al
    . Differentiating BOLD and non-BOLD signals in fMRI time series using multi-echo EPI. Neuroimage 2012;60:1759–70 doi:10.1016/j.neuroimage.2011.12.028 pmid:22209809
    CrossRefPubMed
  24. 24.↵
    1. Popple RA,
    2. Wu X,
    3. Brezovich IA, et al
    . The virtual cone: a novel technique to generate spherical dose distributions using a multileaf collimator and standardized control-point sequence for small target radiation surgery. Adv Radiat Oncol 2018;3:421–30 doi:10.1016/j.adro.2018.02.011 pmid:30197943
    CrossRefPubMed
  25. 25.↵
    1. Li G,
    2. Ballangrud A,
    3. Kuo LC, et al
    . Motion monitoring for cranial frameless stereotactic radiosurgery using video-based three-dimensional optical surface imaging. Med Phys 2011;38:3981–94 doi:10.1118/1.3596526 pmid:21858995
    CrossRefPubMed
  26. 26.↵
    1. Graham MS,
    2. Drobnjak I,
    3. Jenkinson M, et al
    . Quantitative assessment of the susceptibility artefact and its interaction with motion in diffusion MRI. PLoS One 2017;12:e0185647 doi:10.1371/journal.pone.0185647 pmid:28968429
    CrossRefPubMed
  27. 27.↵
    1. Buckner RL,
    2. Krienen FM,
    3. Castellanos A, et al
    . The organization of the human cerebellum estimated by intrinsic functional connectivity. J Neurophysiol 2011;106:2322–45 doi:10.1152/jn.00339.2011 pmid:21795627
    CrossRefPubMedWeb of Science
  28. 28.↵
    1. Middlebrooks EH,
    2. Grewal SS,
    3. Holanda VM
    . Complexities of connectivity-based DBS targeting: rebirth of the debate on thalamic and subthalamic treatment of tremor. Neuroimage Clin 2019;22:101761 doi:10.1016/j.nicl.2019.101761 pmid:30987840
    CrossRefPubMed
  29. 29.↵
    1. Middlebrooks EH,
    2. Tipton P,
    3. Okromelidze L, et al
    . Deep brain stimulation for tremor: direct targeting of a novel imaging biomarker. Ann Neurol 2022;92:341–42 doi:10.1002/ana.26422 pmid:35596936
    CrossRefPubMed
  30. 30.↵
    1. Neudorfer C,
    2. Kroneberg D,
    3. Al-Fatly B, et al
    . Reply to “Deep Brain Stimulation for Tremor: Direct Targeting of a Novel Imaging Biomarker.” Ann Neurol 2022;92:343–44 doi:10.1002/ana.26420 pmid:35608332
    CrossRefPubMed
  31. 31.↵
    1. Akram H,
    2. Dayal V,
    3. Mahlknecht P, et al
    . Connectivity derived thalamic segmentation in deep brain stimulation for tremor. Neuroimage Clin 2018;18:130–42 doi:10.1016/j.nicl.2018.01.008 pmid:29387530
    CrossRefPubMed
  32. 32.↵
    1. Coenen VA,
    2. Allert N,
    3. Paus S, et al
    . Modulation of the cerebello-thalamo-cortical network in thalamic deep brain stimulation for tremor: a diffusion tensor imaging study. Neurosurgery 2014;75:657–69; discussion 6697–70 doi:10.1227/NEU.0000000000000540 pmid:25161000
    CrossRefPubMed
  33. 33.↵
    1. Coenen VA,
    2. Sajonz B,
    3. Prokop T, et al
    . The dentato-rubro-thalamic tract as the potential common deep brain stimulation target for tremor of various origin: an observational case series. Acta Neurochir (Wien) 2020;162:1053–66 doi:10.1007/s00701-020-04248-2 pmid:31997069
    CrossRefPubMed
  34. 34.↵
    1. Coenen VA,
    2. Varkuti B,
    3. Parpaley Y, et al
    . Postoperative neuroimaging analysis of DRT deep brain stimulation revision surgery for complicated essential tremor. Acta Neurochir (Wien) 2017;159:779–87 doi:10.1007/s00701-017-3134-z pmid:28283867
    CrossRefPubMed
  35. 35.↵
    1. Kim W,
    2. Chivukula S,
    3. Hauptman J, et al
    . Diffusion tensor imaging-based thalamic segmentation in deep brain stimulation for chronic pain conditions. Stereotact Funct Neurosurg 2016;94:225–34 doi:10.1159/000448079 pmid:27537848
    CrossRefPubMed
  36. 36.↵
    1. Kim W,
    2. Sharim J,
    3. Tenn S, et al
    . Diffusion tractography imaging-guided frameless linear accelerator stereotactic radiosurgical thalamotomy for tremor: case report. J Neurosurg 2018;128:215–21 doi:10.3171/2016.10.JNS161603 pmid:28298033
    CrossRefPubMed
  37. 37.↵
    1. Gallay MN,
    2. Jeanmonod D,
    3. Liu J, et al
    . Human pallidothalamic and cerebellothalamic tracts: anatomical basis for functional stereotactic neurosurgery. Brain Struct Funct 2008;212:443–63 doi:10.1007/s00429-007-0170-0 pmid:18193279
    CrossRefPubMedWeb of Science
  38. 38.↵
    1. Petersen KJ,
    2. Reid JA,
    3. Chakravorti S, et al
    . Structural and functional connectivity of the nondecussating dentato-rubro-thalamic tract. Neuroimage 2018;176:364–71 doi:10.1016/j.neuroimage.2018.04.074 pmid:29733955
    CrossRefPubMed
  39. 39.↵
    1. Hellwig B,
    2. Haussler S,
    3. Schelter B, et al
    . Tremor-correlated cortical activity in essential tremor. Lancet 2001;357:519–23 doi:10.1016/S0140-6736(00)04044-7 pmid:11229671
    CrossRefPubMedWeb of Science
  40. 40.↵
    1. McAuley JH,
    2. Marsden CD
    . Physiological and pathological tremors and rhythmic central motor control. Brain 2000;123:1545–67 doi:10.1093/brain/123.8.1545
    CrossRefPubMedWeb of Science
  41. 41.↵
    1. Nicoletti V,
    2. Cecchi P,
    3. Pesaresi I, et al
    . Cerebello-thalamo-cortical network is intrinsically altered in essential tremor: evidence from a resting state functional MRI study. Sci Rep 2020;10:16661 doi:10.1038/s41598-020-73714-9 pmid:33028912
    CrossRefPubMed
  42. 42.↵
    1. Archer DB,
    2. Coombes SA,
    3. Chu WT, et al
    . A widespread visually-sensitive functional network relates to symptoms in essential tremor. Brain 2018;141:472–85 doi:10.1093/brain/awx338 pmid:29293948
    CrossRefPubMed
  43. 43.↵
    1. Xiong Y,
    2. Han D,
    3. He J, et al
    . Correlation of visual area with tremor improvement after MRgFUS thalamotomy in Parkinson’s disease. J Neurosurg 2022;136:681–88 doi:10.3171/2021.3.JNS204329 pmid:34479209
    CrossRefPubMed
  44. 44.↵
    1. Tuleasca C,
    2. Najdenovska E,
    3. Regis J, et al
    . Clinical response to VIM’s thalamic stereotactic radiosurgery for essential tremor is associated with distinctive functional connectivity patterns. Acta Neurochir (Wien) 2018;160:611–24 doi:10.1007/s00701-017-3456-x pmid:29335882
    CrossRefPubMed
  45. 45.↵
    1. Gibson WS,
    2. Jo HJ,
    3. Testini P, et al
    . Functional correlates of the therapeutic and adverse effects evoked by thalamic stimulation for essential tremor. Brain 2016;139:2198–210 doi:10.1093/brain/aww145 pmid:27329768
    CrossRefPubMed
  46. 46.↵
    1. Tuleasca C,
    2. Najdenovska E,
    3. Régis J, et al
    . Pretherapeutic motor thalamus resting-state functional connectivity with visual areas predicts tremor arrest after thalamotomy for essential tremor: tracing the cerebello-thalamo-visuo-motor network. World Neurosurg 2018;117:e438–49 doi:10.1016/j.wneu.2018.06.049 pmid:29920392
    CrossRefPubMed
  47. 47.↵
    1. Schlaier JR,
    2. Beer AL,
    3. Faltermeier R, et al
    . Probabilistic vs. deterministic fiber tracking and the influence of different seed regions to delineate cerebellar-thalamic fibers in deep brain stimulation. Eur J Neurosci 2017;45:1623–33 doi:10.1111/ejn.13575 pmid:28391647
    CrossRefPubMed
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American Journal of Neuroradiology: 44 (2)
American Journal of Neuroradiology
Vol. 44, Issue 2
1 Feb 2023
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Connectomic Basis for Tremor Control in Stereotactic Radiosurgical Thalamotomy
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Cite this article
E.H. Middlebrooks, R.A. Popple, E. Greco, L. Okromelidze, H.C. Walker, D.A. Lakhani, A.R. Anderson, E.M. Thomas, H.D. Deshpande, B.A. McCullough, N.P. Stover, V.W. Sung, A.P. Nicholas, D.G. Standaert, T. Yacoubian, M.N. Dean, J.A. Roper, S.S. Grewal, M.T. Holland, J.N. Bentley, B.L. Guthrie, M. Bredel
Connectomic Basis for Tremor Control in Stereotactic Radiosurgical Thalamotomy
American Journal of Neuroradiology Feb 2023, 44 (2) 157-164; DOI: 10.3174/ajnr.A7778

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Connectomics for Tremor Control in Radiosurgery
E.H. Middlebrooks, R.A. Popple, E. Greco, L. Okromelidze, H.C. Walker, D.A. Lakhani, A.R. Anderson, E.M. Thomas, H.D. Deshpande, B.A. McCullough, N.P. Stover, V.W. Sung, A.P. Nicholas, D.G. Standaert, T. Yacoubian, M.N. Dean, J.A. Roper, S.S. Grewal, M.T. Holland, J.N. Bentley, B.L. Guthrie, M. Bredel
American Journal of Neuroradiology Feb 2023, 44 (2) 157-164; DOI: 10.3174/ajnr.A7778
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    Mohammad-Hossein H. K. Nili, Shahrzad M. Esfahan, Yamin Bagheri, Abdol-Hossein Vahabie, Mehdi Sanayei, Abolhassan Ertiaei, Mohammad Shirani, Mohammad-Reza A. Dehaqani, Ehsan Rezayat
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