Case of the Week
Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada
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May 30, 2016
Meningioangiomatosis with Associated Meningioma
- Background:
- Meningioangiomatosis is a rare benign cortical or leptomeningeal hamartomatous lesion characterized by calcifications and meningovascular proliferation
- Rarely, meningioangiomatosis may coexist with other tumors adjacently, most frequently meningioma
- Clinical Presentation:
- Occurs in association with neurofibromatosis type 2 (NF2) in half of cases; may occur sporadically
- Patients may be asymptomatic or manifest with headaches or seizures
- Key Diagnostic Features:
- Nodular, gyriform, globular, or linear cortical/subcortical mass with calcifications
- Variable enhancement (often mild/no enhancement)
- No mass effect
- Differential Diagnoses:
- Oligodendroglioma
- Ganglioglioma
- Calcified meningioma
- Sturge-Weber disease
- Arteriovenous malformation
- Treatment:
- Medical seizure control
- Total resection, for intractable seizure
