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Research ArticleNEUROVASCULAR/STROKE IMAGING

Hypoperfusion Intensity Ratio Less Than 0.4 is Associated with Favorable Outcomes in Unsuccessfully Reperfused Acute Ischemic Stroke with Large-Vessel Occlusion

Vivek Yedavalli, Hamza Adel Salim, Aneri Balar, Dhairya A. Lakhani, Janet Mei, Hanzhang Lu, Licia Luna, Francis Deng, Vaibhav Vagal, Nathan Z. Hyson, Jens Fiehler, Paul Stracke, Gabriel Broocks, Christian Heitkamp, Gregory W. Albers, Max Wintermark, Tobias D. Faizy and Jeremy J. Heit
American Journal of Neuroradiology February 2025, DOI: https://doi.org/10.3174/ajnr.A8518
Vivek Yedavalli
aFrom the Department of Radiology, Division of Neuroradiology (V.Y., H.A.S., J.M., H.L., L.L., F.D., N.Z.H.), Johns Hopkins Medical Center, Baltimore, Maryland
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Hamza Adel Salim
aFrom the Department of Radiology, Division of Neuroradiology (V.Y., H.A.S., J.M., H.L., L.L., F.D., N.Z.H.), Johns Hopkins Medical Center, Baltimore, Maryland
fDepartment of Neuroradiology (H.A.S., M.W.), The University of Texas MD Anderson Center, Houston, Texas
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  • ORCID record for Hamza Adel Salim
Aneri Balar
gDepartment of Radiology, Division of Neuroradiology (A.B., D.A.L.), West Virginia University, Morgantown, WV, USA
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Dhairya A. Lakhani
gDepartment of Radiology, Division of Neuroradiology (A.B., D.A.L.), West Virginia University, Morgantown, WV, USA
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  • ORCID record for Dhairya A. Lakhani
Janet Mei
aFrom the Department of Radiology, Division of Neuroradiology (V.Y., H.A.S., J.M., H.L., L.L., F.D., N.Z.H.), Johns Hopkins Medical Center, Baltimore, Maryland
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Hanzhang Lu
aFrom the Department of Radiology, Division of Neuroradiology (V.Y., H.A.S., J.M., H.L., L.L., F.D., N.Z.H.), Johns Hopkins Medical Center, Baltimore, Maryland
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  • ORCID record for Hanzhang Lu
Licia Luna
aFrom the Department of Radiology, Division of Neuroradiology (V.Y., H.A.S., J.M., H.L., L.L., F.D., N.Z.H.), Johns Hopkins Medical Center, Baltimore, Maryland
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  • ORCID record for Licia Luna
Francis Deng
aFrom the Department of Radiology, Division of Neuroradiology (V.Y., H.A.S., J.M., H.L., L.L., F.D., N.Z.H.), Johns Hopkins Medical Center, Baltimore, Maryland
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Vaibhav Vagal
bRenaissance School of Medicine at Stony Brook University (V.V.), Stony Brook, New York
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Nathan Z. Hyson
aFrom the Department of Radiology, Division of Neuroradiology (V.Y., H.A.S., J.M., H.L., L.L., F.D., N.Z.H.), Johns Hopkins Medical Center, Baltimore, Maryland
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Jens Fiehler
cDepartment of Radiology (J.F., G.B., C.H.), Neuroendovascular Program, University Medical Center Hamburg, Hamburg, Germany
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Paul Stracke
dDepartment of Radiology (P.S., T.D.F.), Neuroendovascular Program, University Medical Center Münster, Münster, Germany
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Gabriel Broocks
cDepartment of Radiology (J.F., G.B., C.H.), Neuroendovascular Program, University Medical Center Hamburg, Hamburg, Germany
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Christian Heitkamp
cDepartment of Radiology (J.F., G.B., C.H.), Neuroendovascular Program, University Medical Center Hamburg, Hamburg, Germany
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Gregory W. Albers
eDepartment of Interventional Neuroradiology (G.W.A., J.J.H.), Stanford Medical Center, Palo Alto, California
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Max Wintermark
fDepartment of Neuroradiology (H.A.S., M.W.), The University of Texas MD Anderson Center, Houston, Texas
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Tobias D. Faizy
dDepartment of Radiology (P.S., T.D.F.), Neuroendovascular Program, University Medical Center Münster, Münster, Germany
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Jeremy J. Heit
eDepartment of Interventional Neuroradiology (G.W.A., J.J.H.), Stanford Medical Center, Palo Alto, California
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Hypoperfusion Intensity Ratio Less Than 0.4 is Associated with Favorable Outcomes in Unsuccessfully Reperfused Acute Ischemic Stroke with Large-Vessel Occlusion
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Cite this article
Vivek Yedavalli, Hamza Adel Salim, Aneri Balar, Dhairya A. Lakhani, Janet Mei, Hanzhang Lu, Licia Luna, Francis Deng, Vaibhav Vagal, Nathan Z. Hyson, Jens Fiehler, Paul Stracke, Gabriel Broocks, Christian Heitkamp, Gregory W. Albers, Max Wintermark, Tobias D. Faizy, Jeremy J. Heit
Hypoperfusion Intensity Ratio Less Than 0.4 is Associated with Favorable Outcomes in Unsuccessfully Reperfused Acute Ischemic Stroke with Large-Vessel Occlusion
American Journal of Neuroradiology Feb 2025, DOI: 10.3174/ajnr.A8518

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HIR in Unsuccessfully Reperfused AIS-LVO Patients
Vivek Yedavalli, Hamza Adel Salim, Aneri Balar, Dhairya A. Lakhani, Janet Mei, Hanzhang Lu, Licia Luna, Francis Deng, Vaibhav Vagal, Nathan Z. Hyson, Jens Fiehler, Paul Stracke, Gabriel Broocks, Christian Heitkamp, Gregory W. Albers, Max Wintermark, Tobias D. Faizy, Jeremy J. Heit
American Journal of Neuroradiology Feb 2025, DOI: 10.3174/ajnr.A8518
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  • Association of Pretreatment Perfusion Imaging Parameters with 90-Day Excellent Functional Outcomes in Anterior Circulation Distal Medium Vessel Occlusion Stroke
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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Association of Pretreatment Perfusion Imaging Parameters with 90-Day Excellent Functional Outcomes in Anterior Circulation Distal Medium Vessel Occlusion Stroke
    Hamza Adel Salim, Vaibhav Vagal, Dhairya A. Lakhani, Janet Mei, Licia Luna, Yasmin Aziz, Aneri Balar, Adam A. Dmytriw, Adrien Guenego, Basel Musmar, Nimer Adeeb, Victor C. Urrutia, Elisabeth B. Marsh, Raf Llinas, Argye E. Hillis, Hanzhang Lu, Risheng Xu, Dylan Wolman, Benjamin Pulli, Kambiz Nael, Max Wintermark, Jeremy J. Heit, Gregory W. Albers, Tobias D. Faizy, Vivek Yedavalli
    American Journal of Neuroradiology 2025 46 5

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  • Perfusion PVT and Longer LOS for Reperfused LVOs
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