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Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2University of British Columbia, Vancouver, British Columbia, Canada
A 15-year-old presents to the emergency department after being hit by a car while riding his bicycle. He has had increasing headaches and vomiting since the accident, with clinical evidence of head trauma with palpable hematoma in the left occipitoparietal region.
A 4-year-old child born of second-degree consanguineous parentage presents to the emergency department in status epilepticus; history of T-cell acute lymphoblastic leukemia diagnosed 8 months back; father had colon cancer and paternal grandmother had cervical cancer; clinical examination shows multiple hyperpigmented macules on the trunk.
A 42-year-old woman with rapidly progressive bilateral visual loss over a span of 3 weeks; prior history of sudden right oculomotor nerve palsy 2 months ago that spontaneously recovered
A 29-year-old woman with a known hematologic disorder presents with altered level of consciousness and respiratory discomfort that began less than 12 hours ago. She reportedly has complaints of pain in the lumbar spine radiating to the lower limbs.
A 45-year-old man with HIV/AIDS for 10 years presented with generalized weakness, headache, and blurring of vision for 2 months. Sputum was positive for acid-fast bacilli. CSF analysis showed raised proteins (331 mg/dL), low glucose (7 mg/dL), and lymphonuclear pleocytosis (85%). CD4 count was 68. Initial brain MRI was performed and the patient was started on antitubercular therapy (ATT) followed by antiretroviral therapy (ART). One and a half months later, the patient presents with neurologic worsening (headache, vomiting, altered sensorium). CD4 counts have risen to 316.
A 44-month-old girl initially presents with glial choristoma ("hairy polyp") of the epipharynx and tongue and subsequent developmental delay.
