A 47-year-old woman with no identified cardiovascular risk factors presents to the emergency department with left-sided hemiparesis, numbness, facial drooping, and dysarthria.
Case of the Week Archive
Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2University of British Columbia, Vancouver, British Columbia, Canada
A 67-year-old man with a history of postmalaria encephalitis 10 years prior develops acute behavioral changes and left-sided involuntary movements. Electroencephalogram fulfills criteria for epilepsia partialis continua.
A 42-year-old man who is a heavy smoker and was recently treated for COVID-19 infection presents with acute myocardial infarction treated with coronary stenting and complicated by severe metabolic acidosis, acute renal failure, and acute pancreatitis. Head CT and subsequent MRI are obtained for evaluation of rapid neurologic deterioration.
A 14-year-old boy with dizziness, vomiting, and headache for the past 6 months
A 21-year-old Chinese man with an 11-year-long worsening of myoclonic epilepsy, ataxia, and cognitive impairment; his father had cerebellar atrophy and his father’s elder sister had epilepsy.
A 71-year-old woman was admitted with a 3-month history of abdominal pain and confusion. Neurologic examination showed mental confusion and diminished tendon reflexes. Blood test showed a severe normocytic anemia. CSF showed albuminocytologic dissociation. EMG demonstrated prolonged distal motor latencies, predominating in the legs. After therapy for 1 month, the patient improved.
A 4-year-old girl followed for gait disorder and cognitive developmental delay
A 47-year-old woman with a life-long history of seizures, panhypopituitarism, and blurry vision
An 8-year-old girl with progressive leg weakness, hyperreflexia, and urinary retention after hyperextending her back during a handstand; CSF analysis was normal, including autoantibodies and oligoclonal bands.
A 51-year-old woman with advanced metastatic breast cancer presents with acute confusion, apraxia, aphasia, and loss of coordination.