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Table of Contents

March 01, 2025; Volume 46,Issue 3

Review Articles

  • FELLOWS' JOURNAL CLUBReview Article
    You have access
    Imaging Findings in Giant Cell Arteritis: Don’t Turn a Blind Eye to the Obvious!
    Girish Bathla, Amit K. Agarwal, Steven A. Messina, David F. Black, Neetu Soni, Felix E. Diehn, Norbert G. Campeau, Vance T. Lehman, Kenneth J. Warrington, Rennie L. Rhee and Thorsten A. Bley
    American Journal of Neuroradiology March 2025, 46 (3) 457-464; DOI: https://doi.org/10.3174/ajnr.A8388

    This pictorial review discusses the various cranial, extracranial, and orbital manifestations of giant cell arteritis on various imaging modalities, including ultrasound, vessel wall imaging, and CTA/MRA.

  • Review Article
    You have access
    Comprehensive Review of the Utility of Dynamic Contrast-Enhanced MRI for the Diagnosis and Treatment Assessment of Spinal Benign and Malignant Osseous Disease
    Atin Saha, Haley Gibbs, Kyung K. Peck, Onur Yildirim, Parsa Nilchian, Sasan Karimi, Eric Lis, Vilma Kosović and Andrei I. Holodny
    American Journal of Neuroradiology March 2025, 46 (3) 465-475; DOI: https://doi.org/10.3174/ajnr.A8398

General Contents

  • Neurovascular/Stroke Imaging
    You have access
    Performance of Automated Algorithm in Large and Medium Vessel Occlusion Detection: A Real-World Experience
    Aakanksha Sriwastwa, Yasmin N. Aziz, Kara Weiss, Robert Buse, Bin Zhang, Stacie L. Demel, Arafat Ali, Sriharsha Voleti, Lily Li-Li Wang and Achala S. Vagal
    American Journal of Neuroradiology March 2025, 46 (3) 476-482; DOI: https://doi.org/10.3174/ajnr.A8509
  • Neurovascular/Stroke Imaging
    You have access
    Hypoperfusion Intensity Ratio Less Than 0.4 Is Associated with Favorable Outcomes in Unsuccessfully Reperfused Acute Ischemic Stroke with Large-Vessel Occlusion
    Vivek Yedavalli, Hamza Adel Salim, Aneri Balar, Dhairya A. Lakhani, Janet Mei, Hanzhang Lu, Licia Luna, Francis Deng, Vaibhav Vagal, Nathan Z. Hyson, Jens Fiehler, Paul Stracke, Gabriel Broocks, Christian Heitkamp, Gregory W. Albers, Max Wintermark, Tobias D. Faizy and Jeremy J. Heit
    American Journal of Neuroradiology March 2025, 46 (3) 483-488; DOI: https://doi.org/10.3174/ajnr.A8518
  • Emergency Neuroradiology
    You have access
    Black Hole Sign under Anticoagulant Therapy: A Retrospective Comparison of Warfarin and Direct Oral Anticoagulants
    Hirotaka Sato, Manabu Kinoshita, Takuma Takano, Takahiro Sanada, Seiya Fujikawa, Masahiro Toda, Kiyoshi Choji and Teruo Kimura
    American Journal of Neuroradiology March 2025, 46 (3) 489-494; DOI: https://doi.org/10.3174/ajnr.A8528
  • EDITOR'S CHOICENeurovascular/Stroke Imaging
    You have access
    Risk Factors for Unfavorable Functional Outcome after Endovascular Treatment of Cerebral Vasospasm following Aneurysmal Subarachnoid Hemorrhage
    Christian Thaler, Bogdana Tokareva, Rabea Wentz, Christian Heitkamp, Matthias Bechstein, Noel van Horn, Vincent Geest, Lasse Dührsen, Hanno S. Meyer, Maxim Bester, Jens Fiehler and Lukas Meyer
    American Journal of Neuroradiology March 2025, 46 (3) 495-501; DOI: https://doi.org/10.3174/ajnr.A8511

    In this study, patients’ individual risk factors, intensity, and extent of cerebral vasospasm associated with poor functional outcomes after endovascular treatment of aneurysmal SAH. Analysis showed an association of higher age, higher Hunt and Hess grades, the occurrence of rebleeding, and bihemispheric vasospasm with unfavorable outcome (mRS 3-6).

  • Neurointervention
    You have access
    Clinical Results of the ANAIS Study: Mechanical Thrombectomy Using the ANA Device in Combination with a Stent Retriever in Subjects with Acute Ischemic Stroke
    Alejandro Tomasello, Joaquín Zamarro, Mikel Terceño, Jose Diaz-Perez, Saima Bashir, Laura Ludovica Gramegna, Manuel Requena, Francesco Diana, Eila Rivera, Marta De Dios, David Hernández, Sonia Sánchez, Inyaki Galve and Marc Ribo
    American Journal of Neuroradiology March 2025, 46 (3) 502-509; DOI: https://doi.org/10.3174/ajnr.A8556
  • Neurointervention
    You have access
    Initial Experience with the Pipeline Vantage Flow Diverter for Intracranial Aneurysms: A Systematic Review and Meta-Analysis
    Jonathan Cortese, Sherief Ghozy, Parya Valizadeh, Alireza Hasanzadeh, Melika Amoukhteh, Payam Jannatdoust, Amir Hassankhani, Ali Ahmadzade, Dan Adrian Popica, David F. Kallmes and Ramanathan Kadirvel
    American Journal of Neuroradiology March 2025, 46 (3) 510-516; DOI: https://doi.org/10.3174/ajnr.A8555
  • Neurointervention
    You have access
    In Vitro Assessment of Vascular Injury following Stent Retriever Retraction in Clinically Relevant Endothelialized Silicone Models
    Isabelle Starr, Harrison Oen, Alyssa McCulloch, Sergey Frenklakh, Ryan Grandfield, Hana Choe and Kristen O’Halloran Cardinal
    American Journal of Neuroradiology March 2025, 46 (3) 517-522; DOI: https://doi.org/10.3174/ajnr.A8495
  • Neurointervention
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    Incidence and Risk Factors of Contrast-Induced Sialadenitis after Therapeutic Neuroendovascular Procedures
    Sang Hyo Lee, Seung Pil Ban, O-Ki Kwon, Young Deok Kim, Yongjae Lee, Chang Wan Oh, Jae Seung Bang, Si Un Lee and Min-Yong Kwon
    American Journal of Neuroradiology March 2025, 46 (3) 523-528; DOI: https://doi.org/10.3174/ajnr.A8492
  • EDITOR'S CHOICEBrain Tumor Imaging
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    Multisite Benchmark Study for Standardized Relative CBV in Untreated Brain Metastases Using the DSC-MRI Consensus Acquisition Protocol
    Sarah Kohn Loizzo, Melissa A. Prah, Min J. Kong, Daniel Phung, Javier C. Urcuyo, Jason Ye, Frank J. Attenello, Jesse Mendoza, Yuxiang Zhou, Mark S. Shiroishi, Leland S. Hu and Kathleen M. Schmainda
    American Journal of Neuroradiology March 2025, 46 (3) 529-535; DOI: https://doi.org/10.3174/ajnr.A8531

    This multisite study found that the consensus DSC-MRI acquisition protocol confirmed the utility of standardized rCBV (srCBV) to identify biologically active, treatment-naïve brain metastases as distinguished from normal-appearing white matter and GBM. The data demonstrated that brain metastases of different primary origins have srCBV values that in general are significantly greater than normal-appearing white matter but significantly lower than srCBV for GBM.

  • Pediatric Neuroimaging
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    CNS Embryonal Tumor with PLAGL Amplification, a New Tumor in Children and Adolescents: Insights from a Comprehensive MRI Analysis
    A. Tietze, B. Bison, J. Engelhardt, T. Fenouil, D. Figarella-Branger, E. Goebell, J. Hakumäki, E. Koscielniak, L.E. Ludlow, D. Meyronet, P. Nyman, I. Øra, J. Pesola, T. Rauramaa, R.E. Reddingius, D. Samuel, A. Sexton-Oates, A. Vasiljevic, A.K. Wefers, J. Zamecnik, D.T.W. Jones, M.K. Keck, K. von Hoff and European Society for Paediatric Oncology (SIOPE)-Brain Tumour Group
    American Journal of Neuroradiology March 2025, 46 (3) 536-543; DOI: https://doi.org/10.3174/ajnr.A8496
  • Artificial Intelligence
    You have access
    Deep Learning–Based ASPECTS Algorithm Enhances Reader Performance and Reduces Interpretation Time
    Angela Ayobi, Adam Davis, Peter D. Chang, Daniel S. Chow, Kambiz Nael, Maxime Tassy, Sarah Quenet, Sylvain Fogola, Peter Shabe, David Fussell, Christophe Avare and Yasmina Chaibi
    American Journal of Neuroradiology March 2025, 46 (3) 544-551; DOI: https://doi.org/10.3174/ajnr.A8491
  • EDITOR'S CHOICEArtificial Intelligence
    You have access
    AI-Generated Synthetic STIR of the Lumbar Spine from T1 and T2 MRI Sequences Trained with Open-Source Algorithms
    Alice M.L. Santilli, Mark A. Fontana, Erwin E. Xia, Zenas Igbinoba, Ek Tsoon Tan, Darryl B. Sneag and J. Levi Chazen
    American Journal of Neuroradiology March 2025, 46 (3) 552-558; DOI: https://doi.org/10.3174/ajnr.A8512

    This proof-of-concept investigation used open-source generative adversarial networks to create synthetic lumbar spine MRI STIR from T1 and T2 sequences. Evaluating radiologists found the synthetic volumes were of equal or better quality in 77% of test patients and demonstrated equivalent or decreased motion artifacts in 78% of test patients. The synthetic volumes had high positive predictive value (75%-100%) but lower sensitivity (0%-67%) for common pathologies. The results from this study are a promising first step toward expediting imaging protocols.

  • Artificial Intelligence
    You have access
    Artificial Intelligence–Generated Editorials in Radiology: Can Expert Editors Detect Them?
    Burak Berksu Ozkara, Alexandre Boutet, Bryan A. Comstock, Johan Van Goethem, Thierry A.G.M. Huisman, Jeffrey S. Ross, Luca Saba, Lubdha M. Shah, Max Wintermark and Mauricio Castillo
    American Journal of Neuroradiology March 2025, 46 (3) 559-566; DOI: https://doi.org/10.3174/ajnr.A8505
  • FELLOWS' JOURNAL CLUBHead and Neck Imaging
    You have access
    Vestibular Schwannoma–Related Increased Labyrinthine Postgadolinium 3D-FLAIR Signal Intensity and Association with Hearing Impairment
    John P. Welby, Nicholas M. Baumel, Ghazal S. Daher, Armine Kocharyan, Christine M. Lohse, Girish Bathla, Matthew L. Carlson, John I. Lane and John C. Benson
    American Journal of Neuroradiology March 2025, 46 (3) 567-571; DOI: https://doi.org/10.3174/ajnr.A8498

    Increased 3D-FLAIR postgadolinium signal intensity of the ipsilateral labyrinth associated with vestibular schwannoma was shown to be correlated with sensorineural hearing loss. The study found that measured intralabyrinthine signal is associated with greater degrees of sensorineural hearing loss on audiometry.

  • Head and Neck Imaging
    You have access
    Prediction of Difficult Round Window Visibility during Cochlear Implantation via a Reformatted CT Facial Recess View: A Retrospective Study with Surgical Correlation
    Si Wei Kheok, Jia Hui Ng, Lishya Liauw, Vanessa Yee Jueen Tan and Jiun Fong Thong
    American Journal of Neuroradiology March 2025, 46 (3) 572-579; DOI: https://doi.org/10.3174/ajnr.A8503
  • Head and Neck Imaging
    You have access
    Imaging of the Hyrtl Fissure: A Rare Cause of Congenital CSF Otorrhea
    Jamie E. Clarke, John Manov, Josephine M. Ndolo, Tangayi Githu, Khushi Saigal and Gaurav Saigal
    American Journal of Neuroradiology March 2025, 46 (3) 580-582; DOI: https://doi.org/10.3174/ajnr.A8525
  • FELLOWS' JOURNAL CLUBSpine Imaging and Spine Image-Guided Interventions
    You have access
    The Many Faces of Myxopapillary Ependymomas
    Ioana Hutuca, Kristof L. Egervari, Doron Merkler and Maria Isabel Vargas
    American Journal of Neuroradiology March 2025, 46 (3) 583-588; DOI: https://doi.org/10.3174/ajnr.A8499

    This clinical report identified the spectrum of MRI characteristics and pathologic patterns of myxopapillary ependymomas. Histopathologic analysis identified a microcystic pattern in larger tumors and a solid pattern in the 4 smaller tumors. The findings suggest a possible association between cases with drop metastases and cases of large tumors with a microcystic pattern.

  • Spine Imaging and Spine Image-Guided Interventions
    You have access
    Patient and Provider Characteristics Associated with the Receipt of Image-Guided Interventions for Low Back Pain
    Ghazaleh Safazadeh, Ruth C. Carlos, Lubdha M. Shah, Gregory J. Stoddard, Rebecca Steed, Troy A. Hutchins and Miriam E. Peckham
    American Journal of Neuroradiology March 2025, 46 (3) 589-596; DOI: https://doi.org/10.3174/ajnr.A8502
  • Spine Imaging and Spine Image-Guided Interventions
    You have access
    Technical Tips for CT-Guided Fibrin Glue Patching of CSF-Venous Fistulas
    Mark D. Mamlouk
    American Journal of Neuroradiology March 2025, 46 (3) 597; DOI: https://doi.org/10.3174/ajnr.A8679
  • Spine Imaging and Spine Image-Guided Interventions
    You have access
    Volumetric Changes of the Choroid Plexus before and after Spinal CSF Leak Repair
    Karen Buch, Aaron Paul, Neo Poyiadji and William A. Mehan
    American Journal of Neuroradiology March 2025, 46 (3) 598-601; DOI: https://doi.org/10.3174/ajnr.A8514
  • Ultra-High-Field MRI/Imaging of Epilepsy/Demyelinating Diseases/Inflammation/Infection
    You have access
    Assessment of Trigeminal Nerve Root Demyelination in Patients with Primary Trigeminal Neuralgia Using Macromolecular Proton Fraction Imaging
    Elena A. Filimonova, Anton A. Pashkov, Vasily L. Yarnykh, Maria I. Schukina, Boris A. Zaitsev, Azniv V. Martirosyan, Galina I. Moysak and Jamil A. Rzaev
    American Journal of Neuroradiology March 2025, 46 (3) 602-610; DOI: https://doi.org/10.3174/ajnr.A8545
  • Ultra-High-Field MRI/Imaging of Epilepsy/Demyelinating Diseases/Inflammation/Infection
    You have access
    Diffusion- and Tractography-Based Characterization of Tissue Damage Within and Surrounding Paramagnetic Rim Lesions in Multiple Sclerosis
    Maryam Mohebbi, Jack A. Reeves, Dejan Jakimovski, Alexander Bartnik, Niels Bergsland, Fahad Salman, Ferdinand Schweser, Bianca Weinstock-Guttman, Robert Zivadinov and Michael G. Dwyer
    American Journal of Neuroradiology March 2025, 46 (3) 611-619; DOI: https://doi.org/10.3174/ajnr.A8524
  • Ultra-High-Field MRI/Imaging of Epilepsy/Demyelinating Diseases/Inflammation/Infection
    You have access
    Multicenter Automated Central Vein Sign Detection Performs as Well as Manual Assessment for the Diagnosis of Multiple Sclerosis
    A.R. Manning, V. Letchuman, M.L. Martin, E. Gombos, T. Robert-Fitzgerald, Q. Cao, P. Raza, C.M. O’Donnell, B. Renner, L. Daboul, P. Rodrigues, M. Ramos, J. Derbyshire, C. Azevedo, A. Bar-Or, E. Caverzasi, P.A. Calabresi, B.A.C. Cree, L. Freeman, R.G. Henry, E.E. Longbrake, J. Oh, N. Papinutto, D. Pelletier, R.D. Samudralwar, S. Suthiphosuwan, M.K. Schindler, M. Bilello, J.W. Song, E.S. Sotirchos, N.L. Sicotte, O. Al-Louzi, A.J. Solomon, D.S. Reich, D. Ontaneda, P. Sati, R.T. Shinohara and the NAIMS Cooperative
    American Journal of Neuroradiology March 2025, 46 (3) 620-626; DOI: https://doi.org/10.3174/ajnr.A8510
  • Ultra-High-Field MRI/Imaging of Epilepsy/Demyelinating Diseases/Inflammation/Infection
    You have access
    DSC MR Perfusion at 7T MRI: An Initial Single-Center Study for Validity and Practicability
    Clare E. Buntrock, Ceren Dinçer, Onur Tuncer, Matthew White, Alexis Swensen, Mark Folkertsma and Can Özütemiz
    American Journal of Neuroradiology March 2025, 46 (3) 627-634; DOI: https://doi.org/10.3174/ajnr.A8513
  • Molecular Neuroimaging/Nuclear Medicine
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    Accuracy and Longitudinal Consistency of PET/MR Attenuation Correction in Amyloid PET Imaging amid Software and Hardware Upgrades
    Chunwei Ying, Yasheng Chen, Yan Yan, Shaney Flores, Richard Laforest, Tammie L.S. Benzinger and Hongyu An
    American Journal of Neuroradiology March 2025, 46 (3) 635-642; DOI: https://doi.org/10.3174/ajnr.A8490

Memorial

  • Memorial
    You have access
    Lee F. Rogers
    Eric J. Russell
    American Journal of Neuroradiology March 2025, 46 (3) 643; DOI: https://doi.org/10.3174/ajnr.A8669

Erratum

  • Erratum
    You have access
    ErratumErratum
    American Journal of Neuroradiology March 2025, 46 (3) 644; DOI: https://doi.org/10.3174/ajnr.A8666
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American Journal of Neuroradiology: 46 (3)
American Journal of Neuroradiology
Vol. 46, Issue 3
1 Mar 2025
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