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Research ArticleHead & Neck

Parotid Gland Atrophy in Patients with Chronic Trigeminal Nerve Denervation

E. Raz, L. Saba, M. Hagiwara, L.C. Hygino de Cruz, P.M. Som and G.M. Fatterpekar
American Journal of Neuroradiology April 2013, 34 (4) 860-863; DOI: https://doi.org/10.3174/ajnr.A3290
E. Raz
aFrom the Department of Radiology (E.R., M.H., G.M.F.), New York University School of Medicine, New York, New York
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L. Saba
bDepartment of Radiology (L.S.), Azienda Ospedaliero Universitaria, Cagliari, Italy
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M. Hagiwara
aFrom the Department of Radiology (E.R., M.H., G.M.F.), New York University School of Medicine, New York, New York
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L.C. Hygino de Cruz Jr
cDepartment of Radiology (L.C.H.d.C.), Clínica de Diagnóstico por Imagem Multi-Imagem, Rio de Janeiro, Brazil
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P.M. Som
dDepartment of Radiology (P.M.S.), Mount Sinai Medical Center, New York, New York.
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G.M. Fatterpekar
aFrom the Department of Radiology (E.R., M.H., G.M.F.), New York University School of Medicine, New York, New York
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  • Fig. 1.
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    Fig. 1.

    Axial image at the level of the mastoid tip of a healthy control demonstrating the parotid segmentation analysis. This quantitative analysis was performed assessing the parotid gland size to obtain a measure of the area in square centimeters for both sides.

  • Fig. 2.
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    Fig. 2.

    Axial T1WI through the skull base demonstrating left trigeminal nerve denervation and atrophy of the ipsilateral left masticator group of muscles. Note that the left parotid gland is markedly atrophic. The right masticator group of muscles and right parotid gland are unremarkable.

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    Fig. 3.

    Axial T1WI in another patient with a left petroclival meningioma demonstrates imaging findings consistent with left trigeminal nerve denervation. Note the atrophy of the ipsilateral parotid gland.

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    Fig. 4.

    Axial T1WI in a patient with right trigeminal schwannoma. Note the atrophy of the right masticator group of muscles, consistent with trigeminal nerve denervation and atrophy of the ipsilateral parotid gland.

Tables

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    Table 1:

    List of patients with trigeminal nerve denervation

    DiseaseSexAge (yr)Atrophy ParotidSide
    Nasopharyngeal tumor, perineural spreadM32YesLeft
    Melanoma cheek, perineural spreadM41YesLeft
    Trigeminal nerve schwannomaF46YesLeft
    IdiopathicM55YesRight
    Metastatic cancer in masticator spaceF29YesRight
    Trigeminal nerve schwannomaM38YesLeft
    Trigeminal nerve schwannomaF42YesRight
    TraumaM51YesRight
    MeningiomaF59YesLeft
    IdiopathicF47YesLeft
    IdiopathicM29YesRight
    TraumaM26NoLeft
    Nasopharyngeal tumor, perineural spreadM45NoLeft
    Trigeminal nerve schwannomaF38NoLeft
    IdiopathicM29NoRight
    Trigeminal nerve schwannomaF38NoRight
    TraumaM53NoLeft
    IdiopathicM54NoLeft
    MeningiomaM64NoRight
    MeningiomaF47NoLeft
    Trigeminal nerve schwannomaM32NoRight
    Nasopharyngeal tumor, perineural spreadF43NoLeft
    MeningiomaM64NoLeft
    IdiopathicF65NoRight
    IdiopathicM54NoLeft
    MeningiomaF24NoLeft
    • View popup
    Table 2:

    2 × 2 Contingency tablea

    DNDTotal
    PA9312
    NP177592
    Total2678104
    • Note:—D indicates trigeminal denervation; ND, nontrigeminal denervation; PA, parotid atrophy; NP, normal parotid.

    • ↵a Fisher exact test for categoric data.

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American Journal of Neuroradiology: 34 (4)
American Journal of Neuroradiology
Vol. 34, Issue 4
1 Apr 2013
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Cite this article
E. Raz, L. Saba, M. Hagiwara, L.C. Hygino de Cruz, P.M. Som, G.M. Fatterpekar
Parotid Gland Atrophy in Patients with Chronic Trigeminal Nerve Denervation
American Journal of Neuroradiology Apr 2013, 34 (4) 860-863; DOI: 10.3174/ajnr.A3290

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Parotid Gland Atrophy in Patients with Chronic Trigeminal Nerve Denervation
E. Raz, L. Saba, M. Hagiwara, L.C. Hygino de Cruz, P.M. Som, G.M. Fatterpekar
American Journal of Neuroradiology Apr 2013, 34 (4) 860-863; DOI: 10.3174/ajnr.A3290
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