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Abstract

MR of intracranial tumors: combined use of gadolinium and magnetization transfer.

T Kurki, P Niemi and S Valtonen
American Journal of Neuroradiology October 1994, 15 (9) 1727-1736;
T Kurki
Department of Diagnostic Radiology, Turku University Hospital, Finland.
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P Niemi
Department of Diagnostic Radiology, Turku University Hospital, Finland.
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S Valtonen
Department of Diagnostic Radiology, Turku University Hospital, Finland.
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Abstract

PURPOSE To study the potential combined application of gadolinium and magnetization transfer in the MR imaging of intracranial tumors.

METHODS Twenty-two patients were imaged at low field strength (0.1 T). Corresponding gradient-echo partial saturation images without and with magnetization transfer pulse were produced. Images with intermediate repetition times were obtained in 18 cases; five different sequences were produced in 4 cases. Gadopentetate dimeglumine was used at a dose of 0.1 mmol/kg.

RESULTS Magnetization transfer effect increased the contrast between enhancing lesion and normal brain and the contrast between edema and normal brain; the contrast between enhancing lesion and edema was not significantly changed. On intermediate-repetition-time magnetization transfer images the contrast between enhancing tumor and normal brain and the contrast between edema and normal brain were superior to short-repetition-time magnetization transfer images, but the differentiation between enhancing tumor and edema was poorer.

CONCLUSION Magnetization transfer can be used to improve contrast in Gd-enhanced MR imaging. Combining magnetization transfer with an intermediate-repetition-time image provides the possibility for displaying both enhancing and nonenhancing lesions on a single MR image.

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American Journal of Neuroradiology
Vol. 15, Issue 9
1 Oct 1994
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T Kurki, P Niemi, S Valtonen
MR of intracranial tumors: combined use of gadolinium and magnetization transfer.
American Journal of Neuroradiology Oct 1994, 15 (9) 1727-1736;

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MR of intracranial tumors: combined use of gadolinium and magnetization transfer.
T Kurki, P Niemi, S Valtonen
American Journal of Neuroradiology Oct 1994, 15 (9) 1727-1736;
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