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Abstract

MR of hippocampal sclerosis: comparison of qualitative and quantitative assessments.

J E Cheon, K H Chang, H D Kim, M H Han, S H Hong, S O Seong, I O Kim, S G Lee, Y S Hwang and H J Kim
American Journal of Neuroradiology March 1998, 19 (3) 465-468;
J E Cheon
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K H Chang
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H D Kim
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M H Han
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S H Hong
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S O Seong
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I O Kim
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S G Lee
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Y S Hwang
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H J Kim
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Abstract

PURPOSE Our goal was to compare the diagnostic accuracy of subjective visual assessment versus MR volumetry in evaluating hippocampal sclerosis and to determine whether MR volumetry is needed in the lateralization of this disease process.

METHODS MR imaging findings were studied retrospectively in 48 patients who underwent surgery for temporal lobe epilepsy and were compared with findings at MR volumetry on an Allegro workstation. Both visual assessment and volumetry were carried out in a blinded fashion with oblique coronal T1-weighted three-dimensional MP-RAGE images obtained on either 1.0-T or 1.5-T units. Normal right-left volumetric differences were recorded in 30 control subjects. The optimum cutoff threshold value for right-left volumetric differences in the sensitivity and specificity of volumetric measurement was obtained from receiver operating characteristic analysis.

RESULTS Sensitivity, specificity, positive and negative predictive values, and accuracy of visual assessment were 86%, 83%, 86%, 83%, and 85%, respectively. For MR volumetry, with the optimum cutoff threshold value of right-left difference at 0.3 cm3, sensitivity, specificity, positive and negative predictive values, and accuracy were 81%, 82%, 87%, 83%, and 85%, respectively.

CONCLUSION Visual assessment was slightly superior to or similar to MR volumetry in assessing unilateral hippocampal sclerosis. MR volumetry of the hippocampus may not be needed for the evaluation of most cases of suspected hippocampal sclerosis.

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American Journal of Neuroradiology
Vol. 19, Issue 3
1 Mar 1998
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MR of hippocampal sclerosis: comparison of qualitative and quantitative assessments.
J E Cheon, K H Chang, H D Kim, M H Han, S H Hong, S O Seong, I O Kim, S G Lee, Y S Hwang, H J Kim
American Journal of Neuroradiology Mar 1998, 19 (3) 465-468;

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MR of hippocampal sclerosis: comparison of qualitative and quantitative assessments.
J E Cheon, K H Chang, H D Kim, M H Han, S H Hong, S O Seong, I O Kim, S G Lee, Y S Hwang, H J Kim
American Journal of Neuroradiology Mar 1998, 19 (3) 465-468;
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  • Lateralizing Ability of Single-voxel Proton MR Spectroscopy in Hippocampal Sclerosis: Comparison with MR Imaging and Positron Emission Tomography
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